CAS: 5465-65-6; 4-Chloro-3-Nitroacetophenone

上下游产品

CAS号99-91-2 对氯苯乙酮 | CAS号857560-77-1 1-(2-amino-4-ch... | CAS号197514-04-8 4-chloro-2-(1,3... | CAS号39061-72-8 1-(2-氨基-4-氯苯基)乙酮 | CAS号89-77-0 2-氨基-4-氯苯甲酸 | CAS号108-90-7 氯苯 | CAS号19688-46-1 1-[4-(2-methoxy... | CAS号19688-55-2 1-(4-[(4-氯苯基)硫代... | CAS号22019-49-4 2-溴-1-(4-氯-3-硝基苯基)乙酮 | CAS号18076-17-0 1-[4-(Methylami... | CAS号79406-57-8 3-氨基-4-氯苯乙酮 | CAS号30877-80-6 1-(3-硝基-4-哌啶苯基)-1-乙酮 | CAS号6277-38-9 4'-甲氧基-3'-硝基乙酰苯 | CAS号144783-46-0 1-(4-吗啉-3-硝基苯基)-1-乙酮 | CAS号133391-57-8 4-Trifluorometh... | CAS号121-89-1 3-硝基苯乙酮

对氯苯乙酮置于硫酸,硝酸体系中,用70.42%的收率获得产物4-氯-3-硝基苯乙酮
参考文献:合成1,2,4-三唑并稠合的1,5-苯并二氮杂,,1,5-苯并恶二氮pine和1,5-苯并噻氮ze骨架的简便方法:一种新型的具有生物意义的七元环系统
标题:合成1,2,4-三唑并稠合的1,5-苯并二氮杂,,1,5-苯并恶二氮pine和1,5-苯并噻氮ze骨架的简便方法:一种新型的具有生物意义的七元环系统
摘要:新的杂环化合物1-(3-甲基-9 H-二苯并[B,F] [1,2,4]三唑并[4,3-D] [1,4]二氮杂pin-6-基)乙酮8A,1-(3-甲基二苯并[B,F] [1,2,4]三唑[4,3-D] [1,4]恶唑啉-6-基)乙酮8B和1-(3-甲基二苯并[B,F] [1,2,4]三唑并[4,3-D] [1,4]噻唑啉-6-基)乙酮8C是由苯并二氮杂酮,苯并恶嗪酮和苯并噻唑酮衍生物合成的.这些杂环支架具有广泛的医学重要性.在针对大肠杆菌的抗菌筛查中获得了最佳结果,阴沟肠杆菌和金黄色葡萄球菌以及对白色念珠菌和尖镰刀菌的真菌筛选.以10,20,30,40和50μg/ Ml的剂量测试了化合物6C,7C和8C的1,1-二苯基-2-吡咯并肼基自由基清除活性,并表示为ic 50值和均值抑制百分比三种不同浓度的合成化合物的+/-标准偏差.通过薄层色谱,元素分析,Ir,1 H-NMR,13
DOI:10.1002/jhet.3060

专利信息

专利号:US-5405872-A
优先权日:1990-09-22
标 题 :Anti-hypertensive tetralins
发明人：MCDERMED JOHN D; HURLEY KEVIN P; CHANG VINCENT H; TADEPALLI ANJANEYULU S
权利人:BURROUGHS WELLCOME CO
摘要:PCT No. PCT/GB91/01602 Sec. 371 Date Mar. 22, 1993 Sec. 102(e) Date Mar. 22, 1993 PCT Filed Sep. 19, 1991 PCT Pub. No. WO92/05143 PCT Pub. Date Apr. 2, 1992.This invention relates to tetralin derivatives useful in medicine for the treatment of hypertension, to the synthesis of the compounds, to the pharmaceutical formulations containing the compounds and the use of the compounds in medical practice.

专利号:RU-2012557-C1
优先权日:1987-05-29
标 题:Method of synthesis of alkanesulfonanilide derivatives or theirs pharmaceutically acceptable salts

专利号:CN-116444436-A
优先权日:2023-03-08
标题 :Synthesis method of aminophenylpyrazole compound