合成目标产物 L-(+)-Tartaric Acid Di-N-Butyl Ester 主要起始原料 Dibenzyl L-Tartrate And 1-Butanol
87-69-4 + 71-36-3 = 87-92-3 + 105-75-9 + 6280-99-5 反应条件:1.1 Catalysts: Molybdenum,Oxobis(8-Quinolinolato-N1,O8)- Solvents: 1-Butanol; 12 H,160 °C 标题:Single-Site Molybdenum Catalyst For The Synthesis Of Fumarate 作者:Jiang,Huifang; Et Al 参考文献:Chemcatchem 日期:2019 卷标:11(17) 页码:4291-4296]
87-69-4 + 71-36-3 = 87-92-3 反应条件:1.1 Catalysts: P-Toluenesulfonic Acid Solvents: Toluene; 5 H,Reflux 标题:Synthesis Of Butyl L-Tartrate 作者:Wei,Yan; Et Al 参考文献:Huaxue Gongchengshi 日期:2007 卷标:21(4) 页码:1-2]
87-69-4 + 71-36-3 = 87-92-3 反应条件:1.1 Catalysts: Palladium Chloride; 5 H,80 °C 标题:Pdcl2-Catalyzed Esterification Of Carboxylic Acids And Transesterification Of Esters 作者:Svirskii,K. S.; Et Al 参考文献:Bashkirskii Khimicheskii Zhurnal 日期:2010 卷标:17(2) 页码:162-164]
87-69-4 + 71-36-3 = 87-92-3 反应条件:1.1 Catalysts: P-Toluenesulfonic Acid Solvents: Cyclohexane; Rt -> 100 °C; 6 H,100 °C1.2 Reagents: Sodium Bicarbonate Solvents: Water 标题:Biobased Plasticizers From Tartaric Acid: Synthesis And Effect Of Alkyl Chain Length On The Properties Of Poly(Vinyl Chloride) 作者:Zhu,Huichao; Et Al 参考文献:Acs Omega 日期:2021 卷标:6(20) 页码:13161-13169]
133-37-9 + 71-36-3 = 87-92-3 反应条件:1.1 Catalysts: P-Toluenesulfonic Acid Solvents: Cyclohexane; 5 H,Reflux 标题:Synthesis And Application Of 2,3-Dihydroxybutanedioic Acid Esters As Efficient Additives In Methanol-Gasoline 作者:Jiang,Xiaoyan; Et Al 参考文献:Asian Journal Of Chemistry 日期:2013 卷标:25(15) 页码:8451-8454
Dibenzyl (2R,3R)-2,3-Dihydroxybutanedioate,正丁醇 以 Various Solvent(S) 作为反应溶剂,化学反应 24.0H,以86.2%的收率获得产物l-酒石酸二丁酯 参考文献:A Convenient Method For Enzymatic Benzyl-Alkyl Transesterification Under Mild Neutral Conditions 标题:A Convenient Method For Enzymatic Benzyl-Alkyl Transesterification Under Mild Neutral Conditions 摘要:Lipases From Candida Cylindracea And From Pseudomonas Fluorescens Efficiently Catalyse The Benzyl To Alkyl Transesterification In Organic Solvents Under Mild Conditions In Nearly Quantitative Yields. DOI:10.1016/s0040-4020(01)89450-3
专利号:US-8178474-B1 优先权日:1999-04-21 标题 :Functionalised solid support for alpha-oxoaldehyde synthesis 发明人:MELNYK OLEG; FRUCHART JEAN-SEBASTIEN; BOUREL LINE; GRAS-MASSE HELENE 权利人:MELNYK OLEG; FRUCHART JEAN-SEBASTIEN; BOUREL LINE; GRAS-MASSE HELENE; PASTEUR INSTITUT; CENTRE NAT RECH SCIENT 摘要:The invention relates to a functionalised solid support for the synthesis of compounds comprising at least one α-oxoaldehyde function, to a process for preparing it and to its applications, in particular for the preparation of a library of organic compounds, of a diagnostic reagent, of a microtitration plate and of a biochip, such as a DNA chip. The present invention also relates to a process for the synthesis of organic compounds comprising at least one α-oxoaldehyde function and to the α-oxoaldehyde peptides obtained using this process.
专利号:US-7812193-B2 优先权日:2003-09-19 标题:Process for enantioselective synthesis of single enantiomers of modafinil by asymmetric oxidation 发明人:REBIERE FRANCOIS; DURET GERARD; PRAT LAURENCE 权利人:CEPHALON FRANCE 摘要:The invention relates to a method for preparing a sulphoxide compound of formula (I) either as a single enantiomer or in an enantiomerically enriched form, comprising the steps of:n a) contacting a pro-chiral sulphide of formula (II) with a metal chiral complex, a base and an oxidizing agent in an organic solvent; and optionally b) isolating the obtained sulphoxide of formula (I); nn nwherein n, Y, R 1 , R 1a , R 2 and R 2a are as defined herein.
专利号:US-2023339839-A1 优先权日:2022-04-24 标题:Synthesis method of alpha-hydroxycarboxylic acid ester 发明人:MENG ZHONGLEI; QIN RONGXIU; GAO SHOUNA; HU GUOJIAO; WEN RUSI; Liao Zhongqiu; LIANG ZHONGYUN; HU LIHONG; ZHOU YONGHONG 权利人:GUANGXI FORESTRY RES INSTITUTE 摘要:A synthesis method of alpha-hydroxycarboxylic acid ester is provided. In the method, an alpha-hydroxycarboxylic acid and an alcohol are taken as raw materials, one or more of boric acid, metaboric acid, pyroboric acid, and boric anhydride is taken as a catalyst, and one of cyclohexane, toluene, benzene, and alcohols is taken as a water-carrying agent. A reaction temperature is kept in range of 100-160° C., produced water is separated by an oil-water separator, and the alpha-hydroxycarboxylic acid ester is synthesized directly. After an esterification reaction, the water-carrying agent and unreacted alcohol are distilled by vacuum fractionation to obtain a crude product, and refined alpha-hydroxycarboxylic acid ester is obtained by performing neutralization, water washing, and vacuum rectification on the crude product. The alpha-hydroxycarboxylic acid ester prepared by the method has high purity and light color, and can be used as green solvent, surfactant, chiral resolution agent and plasticizer.
专利号:US-2005222257-A1 优先权日:2003-09-19 标题:Process for enantioselective synthesis of single enantiomers of modafinil by asymmetric oxidation
专利号:US-7317126-B2 优先权日:2003-09-19 标 题:Process for enantioselective synthesis of single enantiomers of modafinil by asymmetric oxidation
专利号:CA-2538697-C 优先权日:2003-09-19 标 题 :Process for enantioselective synthesis of single enantiomers of modafinil by asymmetric oxidation