CAS: 139756-02-8; 4-Amino-1-Methyl-3-N-Propyl-1H-Pyrazole-5-Carboxamide

上下游产品

CAS号139756-01-7 1-甲基-4-硝基-3-丙基吡... | CAS号139755-99-0 1-甲基-3-丙基-1H-吡唑-5-羧酸 | CAS号139756-00-6 1-甲基-4-硝基-3-丙基-... | CAS号304435-81-2 ethyl 2-(2-(1-c... | CAS号36983-31-0 2,4-二羰基庚酸乙酯 | CAS号133261-07-1 1-甲基-3-正丙基-吡唑-5-甲酸乙酯 | CAS号67-56-1 甲醇 | CAS号304435-83-4 ethyl 4-amino-1... | CAS号139755-85-4 5-(2-乙氧基-5-((4-... | CAS号139756-03-9 4-(2-乙氧基苯甲酰胺基)-... | CAS号139755-83-2 西地那非 | CAS号1093065-15-6 5-[2-ethoxy-5-(... | CAS号139756-21-1 5-(2-乙氧苯基)-1-甲基... | CAS号139756-04-0 1-甲基-4-(2-丙基苯甲酰... | CAS号447417-33-6 1,5-dimethyl-3-...

1-Methyl-4-Nitro-3-Propyl-1H-Pyrazole-5-Carbonyl Chloride置于ammonium Hydroxide,Palladium On Activated Charcoal,氢气体系中,用 四氢呋喃,甲醇 用作溶剂,30.0 °C,344.75 Kpa 条件下,反应 2.0H,反应生成4-氨基-1-甲基-3-正丙基-1H-吡唑-5-羧酰胺
参考文献: Novel Compounds For Use In Cognition Improvement[fr] Nouveaux Composés à Utiliser Pour Améliorer La Cognition
标题: Novel Compounds For Use In Cognition Improvement[fr] Nouveaux Composés à Utiliser Pour Améliorer La Cognition
摘要:用于改善认知的新化合物.涉及具有多环结构和-(C=o)Nrarb基团的某些化合物,其中多环结构包括至少三个环系统,其中一个环系统是包含2至4个环的多环环系统;至少一个环是芳香环;结构中包含至少3个氮原子和1个氧原子.还涉及含有它们的药物组合物,以及它们在医学中的使用,特别是在治疗和/或预防伴有认知缺陷或损害的神经系统疾病或神经退行性疾病中的使用.

专利信息

专利号:US-5719283-A
优先权日:1990-06-20
标 题:Intermediates useful in the synthesis of pyrazolopyrimidinone antianginal agents
发明人：BELL ANDREW SIMON; BROWN DAVID; TERRETT NICHOLAS KENNETH
权利人:PFIZER
摘要:Compounds of the formula ##STR1## wherein R 1 is H, C 1 -C 3 alkyl, C 3 -C 5 cycloalkyl or C 1 -C 3 perfluoroalkyl; n R 2 is H, C 1 -C 6 alkyl optionally substituted by OH, C 1 -C 3 alkoxy or C 3 -C 6 cycloalkyl, or C 1 -C 3 perfluoroalkyl; n R 3 is H, C 1 -C 6 alkyl, C 3 -C 6 alkenyl, C 3 -C 6 alkynyl, C 3 -C 7 cycloalkyl, C 1 -C 6 perfluoroalkyl or (C 3 -C 6 cycloalkyl)C 1 -C 6 alkyl; n and Y is chloro, bromo, or fluoro. n The above compounds are intermediates useful in the synthesis of certain pyrazolopyrimidinones which inhibit cyclic guanosine 3', 5'-monophosphate phosphodiesterase.

专利号:US-6077841-A
优先权日:1998-09-04
标题:5-heterocyclyl pyrazolo[4,3-d]pyrimidin-7-ones for the treatment of male erectile dysfunction
发明人：SUI ZHIHUA; GUAN JIHUA; MACIELAG MARK J
权利人:ORTHO MCNEIL PHARM INC
摘要:The invention is directed to novel substituted 5-heterocyclyl pyrazolopyrimidinones and derivatives thereof, their synthesis and their use in treating sexual dysfunction in mammals, especially male erectile dysfunction. Pharmaceutical compositions containing the compounds and methods of using them to treat sexual dysfunction are also described.

专利号:CN-103044330-B
优先权日:2013-01-14
标 题:A New Process for the Green Synthesis of Sildenafil Intermediate 4-Amino-1-Methyl-3-n-Propylpyrazole-5-Carboxamide

专利号:CN-103044330-A
优先权日:2013-01-14
标 题:A New Process for the Green Synthesis of Sildenafil Intermediate 4-Amino-1-Methyl-3-n-Propylpyrazole-5-Carboxamide

专利号:US-6960661-B2
优先权日:2001-01-27
标题:[7-(3-chloro-4-methoxybenzlamino)-1-methyl-3-propyl-1H-pyrazolo[4,3-d]pyrimidin-5-ylmethoxy]acetic acid, synthesis thereof and intermediates used therein
发明人：EGGENWEILER HANS-MICHAEL
权利人:MERCK PATENT GMBH
摘要:[7-(3-chloro-4-methoxybenzylamino)-1-methyl-3-propyl-1H-pyrazolo[4,3-d]pyrimidin-5-ylmethoxy]acetic acid, n n n is disclosed, as well as a process for its preperation and intermediates in the process of preparing the same.

专利号:CN-115043845-A
优先权日:2022-07-20
标 题 :Synthesis method of sildenafil