CAS: 56621-90-0; 5-Amino-2-Chloropyrimidine

相似化合物

10320-42-0 591-55-9 5177-27-5

上下游产品

CAS号10320-42-0 2-氯-5-硝基嘧啶 | CAS号3264-10-6 2-羟基-5-硝基嘧啶 | CAS号4983-28-2 2-氯-5-羟基嘧啶 | CAS号582323-10-2 N-(2-chloropyri... | CAS号582323-16-8 ICA-069673

2-羟基-5-硝基嘧啶置于三氯氧磷体系中,用 乙酸乙酯 作为反应溶剂,化学反应生成 5-氨基-2-氯嘧啶
参考文献:Pyrimidines As Novel Openers Of Potassium Ion Channels
标题:Pyrimidines As Novel Openers Of Potassium Ion Channels
摘要:本发明提供了一类嘧啶酰胺,可用作钾离子通道的开启剂.该发明的化合物在治疗和诊断方法中均有用途.

专利信息

专利号:US-2022356182-A1
优先权日:2009-03-27
标题 :Inhibitors of hepatitis c virus replication
发明人：COBURN CRAIG A; LUDMERER STEVEN W; LIU KUN; WU HAO; SOLL RICHARD; ZHONG BIN; ZHU JIAN
权利人:MERCK SHARP & DOHME
摘要:The present invention relates to compounds of formula (I) that are useful as hepatitis C virus (HCV) NS5A inhibitors, the synthesis of such compounds, and the use of such compounds for inhibiting HCV NS5A activity, for treating or preventing HCV infections and for inhibiting HCV viral replication and/or viral production in a cell-based system.

专利号:US-11045458-B2
优先权日:2018-07-23
标 题:Synthesis of small molecule histone deacetylase 6 degraders, compounds formed thereby, and pharmaceutical compositions containing them
发明人：TANG WEIPING; Yang Ka; WU HAO
权利人:WISCONSIN ALUMNI RES FOUND
摘要:Histone deacetylase (“HDACâ€?)-selective inhibitors covalently bonded to a linker covalently bonded to an E3 ubiquitin ligase ligand, and salts thereof; pharmaceutical compositions containing them; methods of using the composition to inhibit neoplastic cell growth in mammals, including humans.

专利号:US-11059815-B2
优先权日:2018-07-23
标 题:Synthesis of small molecule histone deacetylase 6 degraders, compounds formed thereby, and pharmaceutical compositions containing them
发明人：TANG WEIPING; Yang Ka; WU HAO; ZHANG ZHONGRUI
权利人:WISCONSIN ALUMNI RES FOUND
摘要:Histone deacetylase (“HDACâ€?)-selective inhibitors covalently bonded to a linker covalently bonded to an E3 ubiquitin ligase ligand, and salts thereof; pharmaceutical compositions containing them; methods of using the composition to inhibit neoplastic cell growth in mammals, including humans.

专利号:US-11053243-B2
优先权日:2009-03-27
标 题:Inhibitors of hepatitis C virus replication
发明人：COBURN CRAIG A; LUDMERER STEVEN W; LIU KUN; WU HAO; SOIL RICHARD; ZHONG BIN; ZHU JIAN
权利人:MERCK SHARP & DOHME
摘要:The present invention relates to compounds of formula (I) that are useful as hepatitis C virus (HCV) NS5A inhibitors, the synthesis of such compounds, and the use of such compounds for inhibiting HCV NS5A activity, for treating or preventing HCV infections and for inhibiting HCV viral replication and/or viral production in a cell-based system.

专利号:US-9090661-B2
优先权日:2009-03-27
标 题:Inhibitors of hepatitis C virus replication
发明人：COBURN CRAIG A; MCCAULEY JOHN A; LUDMERER STEVEN W; LIU KUN; VACCA JOSEPH P; WU HAO; HU BIN; SOLL RICHARD; SUN FEI; WANG XINGHAI; YAN MAN; ZHANG CHENGREN; ZHENG MINGWEI; ZHONG BIN; ZHU JIAN
权利人:MERCK SHARP & DOHME
摘要:The present invention relates to compounds of formula (I) that are useful as hepatitis C virus (HCV) NS5A inhibitors, the synthesis of such compounds, and the use of such compounds for inhibiting HCV NS5A activity, for treating or preventing HCV infections and for inhibiting HCV viral replication and/or viral production in a cell-based system.

专利号:US-2020190079-A1
优先权日:2018-07-23
标题 :Synthesis of small molecule histone deacetylase 6 degraders, compounds formed thereby, and pharmaceutical compositions containing them