CAS: 636-70-4; Triethylamine Hydrobromide

相似化合物

554-68-7 5204-74-0 772-54-3

上下游产品

tetrachloromethane N-Bromosuccinimide triethylamine benzenetetrabutylammomium bromide Triethylammonium perchlorate

溴甲基乙酸酯置于三乙胺体系中,用 丙酮,乙腈 作为反应溶剂,化学反应生成 三乙胺氢溴酸盐
参考文献:2-Oxo-4-Carboxy-Pyrimidines
标题:2-Oxo-4-Carboxy-Pyrimidines
摘要:用于抑制二氢乳清酸酶的化合物,其具有通用公式 (I) 其中 (I) A和b一起是=s 或者 (II) A是-H,B是-Cor₂或-Sr₆;以及 R₁和r₂可以是相同的或不同的,是-Oh;烷氧基甲基,二肽,三肽或多肽基团,-Or,其中r是饱和或不饱和的c1-16烷基,C1-16烷氧基甲基,或4-烷基-哌啶基-烷基,-Nrʹrʹ,其中每个rʹ独立地选自-H,饱和或不饱和的c1-16烷基,或任何能在体内被水解为羟基的基团; R₃和r₄可以是相同的或不同的,是-H,C1-6烷基,羟基c1-16烷基,羟基c1-6醚基团,四氢呋喃基,四氢吡喃基,糖或乙酰化糖基团,己基氨基甲酰基,甲基甘氨酸-N-甲酰基,或任何能在体内被水解为-H的基团; R₅是-H,卤素,或c1-6烷基; R₆是c1-6烷基或1-甲基-4-硝基咪唑-5-基;点线代表的双键可能在4-5位置存在或不存在.这些化合物可用作抗癌症和抗疟疾药物.

专利信息

专利号:US-6683189-B1
优先权日:1996-02-26
标 题 :Method for the synthesis of pyrrole and imidazole carboxamides on a solid support
发明人：DERVAN PETER B; BAIRD ELDON
权利人:CALIFORNIA INST OF TECHN
摘要:The present invention describes a novel method for the solid phase synthesis of polyamides containing imidazole and pyrrole carboxamides. The polyamides are prepared on a solid support from aromatic carboxylic acids and aromatic amines with high stepwise coupling yields (>99%), providing milligram quantities of highly pure polyamides. The present invention also describes the synthesis of analogs of the natural products Netropsin and Distamycin A, two antiviral antibiotics. The present invention also describes a novel method for the solid phase synthesis of imidazole and pyrrole carboxamide polyamide-oligonucleotide conjugates. This methodology will greatly increase both the complexity and quantity of minor-groove binding polyamides and minor-groove binding polyamide-oligonucleotide conjugates which can be synthesized and tested.

专利号:WO-2020246902-A1
优先权日:2019-06-07
标 题 :An initiator of atrp radical polymerisation, a method of its synthesis, and a method of synthesis of low-dispersion polymer and copolymer using this initiator
发明人：MEGIEL ELÅ»BIETA; ROMAŃSKI JAN; FEDORCZUK MAGDALENA
权利人:UNIV WARSZAWSKI
摘要:An initiator of ATRP radical polymerisation having a functional group with a substituent active in polymerisation process, is characterised in that it is a bifunctional initiator containing at least two functional groups separated by a hydrocarbon moiety Y, where the first functional group has an active substituent X and the second functional group has a protecting group Z, which can be chemically modified with the same or a different substituent than the active substituent X present in the first functional group. A method of synthesis of 2-chloro-N-(2-hydroxyethyl)propionamide initiator, NCPAE, is characterised in that ethanolamine is subjected to an acylation reaction with 2-chloropropionyl chloride in presence of triethylamine (TEA), wherein the reaction is carried out under inert atmosphere at room temperature.

专利号:US-7674876-B2
优先权日:2005-05-25
标题:Synthesis of novel monomers containing the trifluorovinylidene group and the cyanato group and polymers thereof
发明人：DREYER CHRISTIAN; BAUER MONIKA; IYER SURESH S; SMITH DENNIS W
权利人:FRAUNHOFER GES FORSCHUNG; UNIV CLEMSON
摘要:Novel hybrid monomers containing both the aryltrifluorovyinyloxyether-group (TFVE-group) and the cyanato-group, their synthesis, and the synthesis of polymers made from these new hybrid monomers are disclosed.

专利号:US-4515920-A
优先权日:1984-04-30
标题 :Synthesis of peptides and proteins
发明人：ERICKSON BRUCE W
权利人:UNIV ROCKEFELLER
摘要:Solid phase synthesis of peptides and proteins have been improved by the use of a trifunctional segment, one functional group of which is bound to a solid support, the other two functional groups being available as substrates upon which identical proteins are synthesized.

专利号:US-6933382-B2
优先权日:2002-12-31
标题:Process for the synthesis of 2-deoxy-D-glucose
发明人：MEREYALA HARI BABU; KUMAR MAMIDYALA SREEMAN
权利人:COUNCIL SCIENT IND RES
摘要:The present invention provides a process for the synthesis of 2-deoxy-D-glucose comprising haloalkoxylation of R-D-Glucal wherein R is selected from H and 3, 4, 6-tri-O-benzyl, to obtain alkyl 2-deoxy-2-halo-R-α/β-D-gluco/mannopyranoside, converting alkyl 2-deoxy-2-halo-R-α/β-D-gluco/mannopyranoside by reduction to alkyl 2-deoxy-α/β-D-glucopyranoside, hydrolysing alkyl 2-deoxy-α/β-D-glucopyranoside to 2-deoxy-D-glucose.

专利号:US-7125983-B2
优先权日:2000-11-29
标题:L-nucleic acid derivatives and process for the synthesis thereof
发明人：IIZUKA HAJIME; TOGASHI KAZUHIKO; SUZUKI TSUNEJI
权利人:MITSUI CHEMICALS INC
摘要:A novel method has been found to produce 2,2′-anhydro-1-(β-L-arabinofuranosyl)thymine as a novel useful intermediate compound. A novel method has been further found to produce thymidine from 2,2′-anhydro-1-(β-L-arabinofuranosyl)thymine. A novel method has been further found to L-2′-deoxyribose derivatives as a useful synthetic intermediate through L-2,2′-anhydro-5,6-dihydrocyclouridine derivative. According to these methods, synthesis of various L-nucleic acid derivatives, synthesis of which has been difficult till now.