CAS: 1460-02-2; 1,3,5-Tri-Tert-Butylbenzene

该化合物其结构特征为:在1,3和5个位置上,以三丁基苯环替换为三丁基苯环,这种安排导致一个高度分枝和大宗的分子,造成其独特的物理和化学特性;该化合物在室内温度下一般没有颜色,在黄色固体中是无色的,在水中可溶性较低,同时在有机溶剂中更易溶解;它具有高热稳定性,耐氧化性,在各种工业应用中有用,包括作为润滑剂和燃料的添加剂;此外,由于能够增强材料的热性能,已经对其作为阻燃剂和聚合化学中的潜力进行了研究,1,3,5-t-ter-ter-t-buty-benzenehene进行了研究;其相对低的毒性和环境影响进一步有助于其在化学制造和研究中的吸引力.

英文名称1,3,5-Tri-Tert-Butylbenzene
中文名称1,3,5-三叔丁基苯
IUPAC名称1,3,5-tri-tert-butylbenzene
其它别名1,3,5-三-特-丁基苯; 135三叔丁基苯; Benzene,1,3,5-Tri(1,1-Dimethylethyl)-; 1,3,5-Tri-Tert-Butylbenzene
CAS编号1460-02-2
MFCD编号:MFCD00008831
EINECS号:215-952-4
FDA UNII编号:Z9HH57K5V2
分子式:C18H30
分子量:246.44
产品CID: 693562
产品分类有机原料→分子砌块→芳环类化合物→苯类化合物

相似结构搜索
产品信息参考
InChIKey: GUFMBISUSZUUCB-UHFFFAOYSA-N
InChI=1S/C18H30/c1-16(2,3)13-10-14(17(4,5)6)12-15(11-13)18(7,8)9/h10-12H,1-9H3…
计算化学: 氢键受体数0.0氢键供体数0.0可旋转键数0.0

相似化合物

15181-11-0 1014-60-4 98-19-1

物理性质

熔点67-72°C
沸点248°C at 760 mmHg
闪点99.1±7.3 °C
密度0.9±0.1 g/cm3
PSA:0.0
LogP:5.5791
折射率1.474
蒸汽压0.0±0.2 mmHg at 25°C
溶解性Chloroform (Sparingly), Ethyl Acetate (Slightly)
敏感性如果遵照规格使用和储存则不会分解，未有已知危险反应，避免氧化物
外观形态白色至类白色固体
储存条件密封, 常温干燥保存
产品应用该化合物用于制作,和离子的三明治复合体.

MSDS等安全信息

GHS象形图
GHS符号GHS07;
注释: Exclamation mark
危险类别特定目标器官毒性 - 单次接触类别3
皮肤腐蚀/刺激类别2
严重眼刺激类别2
急性毒性类别4(吸入)
急性毒性类别4(经皮)
急性毒性类别4(经口)
水生慢性毒性类别4
警示词Warning(警告)
危险描述H335 |可能引起呼吸道刺激.
H315 |造成皮肤刺激.
H319 |造成严重眼刺激.
H332 |吸入有害.
H312 |皮肤接触有害.
H302 |吞咽有害.
H413 |可能对水生生物造成长期有害影响.
防范说明P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
危险品标志N
安全声明22-24/25
WGK Germany3

欧盟法规

REACH注册ECHA物质ECHA物质C&L通报REACH预注册

上下游产品

合成工艺路线路线简述

频哪酮置于sodium体系中,化学反应生成1,3,5-三叔丁基苯
参考文献:1,3,5-Tri-T-Butylbenzene And Some Derivatives1
标题:1,3,5-Tri-T-Butylbenzene And Some Derivatives1
摘要:
Doi:10.1021/ja01638A019

海关参考信息

2902600000-乙苯
2902700000-异丙基苯
💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
详情请参考：📖 海关编码查询和海关进出口税则

专利信息

专利号:US-11999757-B2
优先权日:2017-11-01
标题:Synthesis of boronate ester derivatives and uses thereof
发明人：BOYER SERGE HENRI; HECKER SCOTT J; VERZIJL GERARDUS K M; HERMSEN PETRUS J
权利人:MELINTA SUBSIDIARY CORP
摘要:Disclosed herein are methods for the preparation of boronate derivatives in the synthesis of antimicrobial compounds and uses thereof. Disclosed herein includes method of making a compound of Formula (B) by reducing the ketone group of the keto-ester compound of Formula (A), and the reduction can be performed using a Ruthenium based catalyst system or using an alcohol dehydrogenase bioreduction system.

专利号:US-10669292-B2
优先权日:2014-05-05
标题 :Synthesis of boronate salts and uses thereof
发明人：HECKER SCOTT; BOYER SERGE
权利人:REMPEX PHARMACEUTICALS INC
摘要:Disclosed herein are boronate intermediates in the synthesis of antimicrobial compounds and the use and preparation thereof. Some embodiments relate to crystalline boronate salt derivatives and their use in the synthesis of therapeutic compounds.

专利号:WO-9955664-A1
优先权日:1998-04-24
标题 :Preparation of carbocyclic compounds
发明人：BECKER MARK W; CHAPMAN HARLAN H; KELLY DAPHNE E; KENT KENNETH M; LEW WILLARD; LOUIE MICHAEL S; MCGEE LAWRENCE R; PRISBE ERNEST J; POSTICH MICHAEL J; ROHLOFF JOHN C; SCHULTZE LISA M; YU RICHARD H; ZHANG LIJUN
权利人:GILEAD SCIENCES INC; BECKER MARK W; CHAPMAN HARLAN H; KELLY DAPHNE E; KENT KENNETH M; LEW WILLARD; LOUIE MICHAEL S; MCGEE LAWRENCE R; PRISBE ERNEST J; POSTICH MICHAEL J; ROHLOFF JOHN C; SCHULTZE LISA M; YU RICHARD H; ZHANG LIJUN
摘要:The present invention provides new synthetic methods and compositions. In particular, new methods of preparing intermediates useful in the synthesis of neuraminidase inhibitors and compositions useful as intermediates that are themselves useful in the synthesis of neuraminidase inhibitors are provided.

专利号:US-6518438-B2
优先权日:1996-08-23
标题:Preparation of cyclohexene carboxylate derivatives
发明人：KENT KENNETH M; KIM CHOUNG U; MCGEE LAWRENCE R; MUNGER JOHN D; PRISBE ERNEST J; POSTICH MICHAEL J; ROHLOFF JOHN C; KELLY DAPHNE E; WILLIAMS MATTHEW A; ZHANG LIJUN
权利人:GILEAD SCIENCES INC
摘要:The present invention provides new synthetic methods and compositions. In particular, new methods of preparing intermediates useful in the synthesis of neuraminidase inhibitors and compositions useful as intermediates that are themselves useful in the synthesis of neuraminidase inhibitors are provided.

专利号:US-5886213-A
优先权日:1997-08-22
标题:Preparation of carbocyclic compounds
发明人：KENT KENNETH M; KIM CHOUNG U; MCGEE LAWRENCE R; MUNGER JOHN D; PRISBE ERNEST J; POSTICH MICHAEL J; ROHLOFF JOHN C; KELLY DAPHNE E; WILLIAMS MATTHEW A; ZHANG LIJUN
权利人:GILEAD SCIENCES INC
摘要:The present invention provides new synthetic methods and compositions. In particular, new methods of preparing intermediates useful in the synthesis of neuraminidase inhibitors and compositions useful as intermediates that are themselves useful in the synthesis of neuraminidase inhibitors are provided.

专利号:US-6204398-B1
优先权日:1996-08-23
标题 :Preparation of cyclohexene carboxylate derivatives
发明人：KENT KENNETH M; KIM CHOUNG U; MCGEE LAWRENCE R; MUNGER JOHN D; PRISBE ERNEST J; POSTICH MICHAEL J; ROHLOFF JOHN C; KELLY DAPHNE E; WILLIAMS MATTHEW A; ZHANG LIJUN
权利人:GILEAD SCIENCES INC
摘要:The present invention provides new synthetic methods and compositions. In particular, new methods of preparing intermediates such as those having formulas (I)-(IV), useful in the synthesis of neuraminidase inhibitors and compositions useful as intermediates that are themselves useful in the synthesis of neuraminidase inhibitors are provided.