CAS: 7774-74-5; Thiophene-2-Thiol

上下游产品

CAS号1227941-25-4 3-(thiophen-2-y... | CAS号188290-36-0 Thiophene(SIV) | CAS号87947-35-1 S-thiophen-2-yl... | CAS号16629-19-9 2-噻吩磺酰氯 | CAS号1003-09-4 2-溴噻吩 | CAS号2786-07-4 2-噻吩基锂 | CAS号33892-56-7 2-allylsulfanyl... | CAS号74-86-2 乙炔 | CAS号120665-65-8 4-(2-thienylthi... | CAS号5713-61-1 2-噻吩基溴化镁 | CAS号111190-17-1 3-methyl-3-thio... | CAS号188290-36-0 Thiophene(SIV) | CAS号7774-73-4 3-巯基噻吩 | CAS号236-65-7 Bisthieno[2,3-b... | CAS号3593-75-7 二噻吩[3,2-B:2',3'-D]噻吩 | CAS号492-97-7 2,2'-双噻吩 | CAS号3807-37-2 2-(3-噻吩基硫代)噻吩 | CAS号3988-99-6 2-(2-噻吩基硫)噻吩 | CAS号5780-36-9 2-(甲基硫代)噻吩 | CAS号22552-36-9 Thiophene,2-[(2...

2-噻吩基锂置于1,2,3,4,5,6,7,8-八硫杂环辛烷体系中,化学反应生成 2-噻吩硫醇
参考文献:Preparation Of Oligo(Thio-2,5-Thienylenes)
标题:Preparation Of Oligo(Thio-2,5-Thienylenes)
摘要:
DOI:10.1021/jo960926I

专利信息

专利号:US-5760249-A
优先权日:1995-08-29
标题 :Synthesis of hydroxysulfone and related compounds
发明人：MATHRE DAVID J; SOHAR PAUL; MOODY DAVID; BLACKER ANDREW J
权利人:MERCK & CO INC; ZENECA LTD
摘要:This invention is concerned with an improved process for the synthesis of hydroxysulfone, which is a key intermediate in the synthesis of carbonic anhydrase inhibitors, especially dorzolamide. Carbonic anhydrase inhibitors are known to be effective in treating elevated intraocular pressure or glaucoma.

专利号:US-2024024489-A1
优先权日:2020-11-20
标 题:Protected disaccharides, their process of preparation and their use in the synthesis of zwitterionic oligosaccharides, and conjugates thereof
发明人：MULARD LAURENCE; DHARA DEBASHIS; PFISTER HELENE; PAOLETTI JULIE; PHALIPON ARMELLE; GUERREIRO-INVERNO CATHERINE
权利人:PASTEUR INSTITUT
摘要:The present invention provides zwitterionic oligosaccharides, in particular fragments of the surface polysaccharides from Shigella sonnei and Shigella sonnei conjugates comprising them. The present invention also provides protected disaccharides, their process of preparation and their use in the synthesis of zwitterionic oligosaccharides, and conjugates thereof, the disaccharide repeating unit of Shigella sonnei being: (I)

专利号:US-5574176-A
优先权日:1995-04-26
标题:Synthesis of an intermediate for the preparation of 5,6-dihydro-(s)-4-(ethylamino)-(s)-6-methyl-4h-thieno [2,3-b]thiopyran-2-sulfonamide 7,7-dioxide intermediates and related compounds
发明人：MATHRE DAVID J; SOHAR PAUL; BROWN LYNN M
权利人:MERCK & CO INC
摘要:This invention is concerned with an improved process for the synthesis of and intermediate en route to 5,6-dihydro-(s)-4-(ethylamino)-(s)-6-methyl-4h-thieno[2,3-b]thiopyran-2-sulfonamide 7,7-dioxide and related compounds. The instant process reduces the reaction time for the synthesis of the key intermediate from 3 to 4 days to from about 2 to about 4 hours while retaining the high enantiomeric purity of the product.

专利号:EP-0853625-B1
优先权日:1995-08-29
标 题:Synthesis of hydroxysulfone and related compounds
发明人：MATHRE DAVID J; SOHAR PAUL; MOODY DAVID; BLACKER ANDREW J
权利人:MERCK & CO INC; SYNGENTA LTD
摘要:This invention is concerned with an improved process for the synthesis of hydroxysulfone, which is a key intermediate in the synthesis of carbonic anhydrase inhibitors, especially dorzolamide. Carbonic anhydrase inhibitors are known to be effective in treating elevated intraocular pressure or glaucoma.

专利号:US-4968815-A
优先权日:1990-04-16
标题 :Synthesis of (S)-3-(thien-2-ylthio)butyric acid analogs
发明人：BLACKLOCK THOMAS J; SHINKAI ICHIRO
权利人:MERCK & CO INC
摘要:(S)-3-(thien-2-ylthio)butyric acid analogs are intermediates in the synthesis of the chiral (S,S)-5,6-dihydro-4-ethylamino-6-methyl-4H-thieno[2,3-b]thiopyran-2-sulfonamide-7,7-dioxide and analogs thereof, topically effective carbonic anhydrase inhibitors useful in the treatment of ocular hypertension and glaucoma. They are prepared by condensation of 2-mercaptothiophene and (R)-(+)-β-methyl-β-propiolactone or an analog thereof.

专利号:US-4968814-A
优先权日:1990-04-18
标题:(S)-Alkyl 3-(thien-2-ylthio)butyrate and analogs and synthesis thereof
发明人：BLACKLOCK THOMAS J; GRABOWSKI EDWARD J J; SOHAR PAUL
权利人:MERCK & CO INC
摘要:(S)-Alkyl 3-(thien-2-ylthio)butyrate and analogs are intermediates in the synthesis of the chiral (S,S)-5,6-dihydro-4-ethylamino-6-methyl-4H-thieno[2,3-b]thiopyran-2-sulfonamide-7,7-dioxide and analogs thereof, topically effective carbonic anhydrase inhibitors useful in the treatment of ocular hypertension and glaucoma.