612-16-8 = 135-02-4 + 80866-82-6 反应条件:1.1 Reagents: N-Bromosuccinimide Solvents: 1,4-Dioxane,Water; 1 H,25 - 30 °C 标题:N-Bromosuccinimide. A Facile Reagent For The Oxidation Of Benzylic Alcohols To Aldehydes 作者:Adimurthy,Subbarayappa; Et Al 参考文献:Synthetic Communications 日期:2007 卷标:37(9) 页码:1571-1577
专利号:US-5861532-A 优先权日:1997-03-04 标 题:Solid-phase synthesis of N-alkyl amides 发明人:BROWN EDWARD G; NUSS JOHN M 权利人:CHIRON CORP 摘要:Methods for solid phase synthesis of N-alkyl amides comprise reductive amination of carbonyl compounds using a reducing agent and an amine-containing linker bound to a solid support. The methods afford high yields of linker-bound, monoalkylated amines, and subsequent coupling with acid derivatives provide derivatized N-substituted amides in excellent yields after cleavage from the solid-phase. Compositions useful in solid phase synthesis are also described.
专利号:US-6524446-B2 优先权日:2001-03-27 标 题 :Process for synthesis of a porphyrin compound using a molecular sieve catalyst under microwave irradiation 发明人:KULKARNI SHIVANAND JANARDAN; RAGHAVAN KONDAPURAM VIJAYA; MOTKURI RADHA KISHAN; NAGABANDI SRINIVAS 权利人:COUNCIL SCIENT IND RES 摘要:The present invention provides an improved process for synthesis of porphyrin compounds of the general formula 1 n from pyrrole and aromatic aldehyde over zeolite molecular sieve catalysts using microwave heating, (solvent free) to provide an eco-friendly, economical, faster and selective heterogeneous method.
专利号:US-5679864-A 优先权日:1995-11-03 标题:Process for the synthesis of curcumin-related compounds 发明人:KRACKOV MARK HARRY; BELLIS HAROLD EDWARD 权利人:GENE PRINT INC 摘要:The invention is directed to a process for the synthesis of curcumin and curcumin-related compounds by reacting the enol form of a 2,4-diketone with a monocarbocyclic aldehyde in the presence of an organic amine catalyst. The reactants are dissolved in a highly polar, aprotic organic solvent. The curcumin-related product is recovered in crystalline form by precipitation from the reaction mass and solvent recrystallization.
专利号:WO-2017089470-A1 优先权日:2015-11-27 标 题:Process for the synthesis of aryldiazonium salts using nitrogen oxides in oxygen-containing gas streams, especially from industrial waste gases 发明人:HOFMANN DAGMAR; HOFMANN JOSEFA; HEINRICH MARKUS 权利人:Friedrich-Alexander-Universität Erlangen-Nürnberg 摘要:The present invention relates to a process for the synthesis of aryldiazonium salts using nitrogen oxides in oxygen-containing gas streams, especially from industrial waste gases.
专利号:WO-0056708-A1 优先权日:1999-03-19 标题 :Catalytic asymmetric synthesis of chiral aziridines 发明人:WULFF WILLIAM D; ANTILLA JON 权利人:ARCH DEV CORP 摘要:The present invention relates to the synthesis of chiral cis-aziridines (IIIa and IIIb) by reacting an imine (I) with a diazo compound (II) in the presence of a chiral vaulted biaryl-Lewis Acid complex as shown.
专利号:US-2013338369-A1 优先权日:2011-03-07 标 题 :Process for the Synthesis of Aminobiphenylene 发明人:HEINRICH MARKUS; PRATSCH GERALD 权利人:HEINRICH MARKUS; PRATSCH GERALD; BASF SE 摘要:The present invention relates to a process for the synthesis of 2-aminobiphenylene and derivatives thereof by reacting a benzene diazonium salt with an aniline compound under basic reaction conditions.
[参考文献]: Sheikh Shreaz, Et Al. Interesting Anticandidal Effects Of Anisic Aldehydes On Growth And Proton-Pumping-Atpase-Targeted Activity. Microb Pathog. 2011 Oct;51(4):277-84. [参考文献]: Zhaoxiang Huang, Et Al. Synergistic Effects Of Cinnamaldehyde And Cinnamic Acid In Cinnamon Essential Oil Against S. Pullorum. Industrial Crops And Products, 2021-02-03. [参考文献]: Chao-Bin Xue, Et Al. 3D-Qsar And Molecular Docking Studies Of Benzaldehyde Thiosemicarbazone, Benzaldehyde, Benzoic Acid, And Their Derivatives As Phenoloxidase Inhibitors. Bioorg Med Chem. 2007 Mar 1;15(5):2006-15. [参考文献]: Eun-Young Jeong, Et Al. Food Protective Effects Of Periploca Sepium Oil And Its Active Component Against Stored Food Mites. J Food Prot. 2012 Jan;75(1):118-22. [参考文献]: Zhi-Huai Li, Et Al. Noncovalent Immobilization Of Ionic-Tagged Box-Cu(Oac)2 Complex And Its Application In Asymmetric Henry Reaction. Chirality. 2012 Dec;24(12):1092-5.
合成参考文献
摘要:Takeda, T.; Tsubouchi, A., Science of Synthesis, (2010) 47, 247. 摘要:Koo, S., Science of Synthesis, (2010) 45, 1370. 摘要:Dissanayake, P.; Averill, D. J.; Allen, M. J., Science of Synthesis Knowledge Updates, (2011) 4, 7. 摘要:Li, W.; Liu, X. H.; Feng, X. M., Science of Synthesis Knowledge Updates, (2021) 1, 41. 摘要:Wu, X.-F., Science of Synthesis Knowledge Updates, (2014) 1, 255.