CAS: 13505-32-3; (S)-2-(4-Methylphenylsulfonamido)-3-Phenylpropanoic Acid

该化合物是一个氨酸衍生物,其特征是附于苯丙烯侧链氮的聚苯乙烯(p-tolenesulfonyl)组,该化合物通常用于有机合成和丙酸化学,因为它能够保护氨酸和丙酸,便于有选择地改变氨酸和丙酸.该聚氨酯组增强化合物在有机溶剂中的稳定性和溶性,使其成为各种化学反应中的一种有价值的试剂.N-P-tosyl-L-苯麻拉尼在外表上一般是白色对非白的,在极有机溶剂中是溶解的,其结构有助于合成更复杂的分子,特别是在制药和生物活性化合物的研制中.此外,源自L-苯丙胺成分的化合物的性能在生物系统中非常突出,影响与酶和受体的相互作用.

结构式图片

相似化合物

86117-53-5 1161-13-3 13734-34-4

欧盟法规

C&L通报

上下游产品

1-°Ctyn-3-ol N-(p-toluenesulfonyl)-L-phenylalanyl chloride 7-(N-tosyl-L-phenylalanyl)amino-4-nitrobenzo-2-oxa-1,3-diazole L-phenylalanineN-(p-toluenesulfonyl)-L-phenylalanyl chloride (S)-3-Phenyl-N-pyrimidin-2-yl-2-(toluene-4-sulfonylamino)-propionamide L-phenylalanine D-(R)-phenylalanine

合成工艺路线路线简述

  • 34635-34-2 = 13505-32-3 + 86117-53-5
    反应条件:1.1 Reagents: (3R,5R,6S,8R)-1,3,4,5,6,7,8,10-Octahydro-5,6-Bis(2-Hydroxyphenyl)-3,8-Bis(Phenyl... Solvents: Chloroform-D; Rt
    标题:Synthesis Of Macrocycles And Their Application As Chiral Solvating Agents In The Enantiomeric Recognition Of Carboxylic Acids And α-Amino Acid Derivatives
    作者:Guo,Shengnan; Et Al
    参考文献:Tetrahedron: Asymmetry 日期:2013 卷标:24(8) 页码:480-491
N-(对甲苯磺酰基)苯丙氨酸(9-甲氧基-3-氧代-3H-苯并[f]苯并吡喃-1-基)甲酯 以 乙腈 用作溶剂,化学反应生成N-(对甲苯磺酰)-L-苯丙氨酸
参考文献:氧代苯并[ F ]苯并吡喃类作为新的对羧基具有功能的荧光光不稳定保护基
标题:氧代苯并[ F ]苯并吡喃类作为新的对羧基具有功能的荧光光不稳定保护基
摘要:研究了三个氧代苯并[ F ]苯并吡喃类作为新的对氨基酸的羧基官能团的光不稳定保护基的性质.荧光氨基酸缀合物得到了有效的制备和表征.这些化合物的光脱保护是通过在300,350和419 Nm处进行辐照进行的,最短的辐照时间和非常好的脱保护收率是最合适的波长是350 Nm.
Doi:10.1016/j.Tet.2006.09.085

海关参考信息

专利信息


专利号:US-7588887-B2
优先权日:1998-08-31
标题 :Stable isotope metabolic labeling for analysis of biopolymers
发明人:FRANZA JR B ROBERT; ROCHON YVAN P
权利人:UNIV WASHINGTON
摘要:Methods for the determination of the rate of synthesis of biopolymer synthesis and degradation in cells, tissues, or cell-free systems using monomer which has been labeled with a stable isotope are provided. Further, the present invention provides methods for the determination or identification of an unknown biopolymer and for the identification of an unknown cell type, a physiological state of a cell or tissue. Also, the present invention provides a database of descriptors which can be used to define an organism, tissue type, cell type, and the like, and which database can be used in conjunction with other public and private databases to identify or characterize an organism, tissue type, cell type, state of differentiation, or physiologic state of an organism, or tissue or cell sample.

专利号:US-10947231-B2
优先权日:2009-05-27
标题:Processes for the preparation of substituted tetrahydro beta-carbolines
发明人:HWANG PETER SEONGWOO; MOON YOUNG-CHOON; TAMIL ARASU; QI HONGYAN; ALMSTEAD NEIL
权利人:PTC THERAPEUTICS INC
摘要:Provided herein are improved processes for the synthesis of substituted tetrahydro beta-carboline derivatives. In particular, provided herein are improved processes useful for the preparation of (S)-4-chlorophenyl 6-chloro-1-(4-methoxyphenyl)-3,4-dihydro-1H-pyrido[3,4-b]indole-2(9H)-carboxylate. Formula (I):

专利号:US-9217012-B2
优先权日:2009-04-08
标题 :Inhibitors of protein tyrosine phosphatases
发明人:ZHANG ZHONG-YIN; ZHANG SHENG
权利人:ZHANG ZHONG-YIN; ZHANG SHENG; UNIV INDIANA RES & TECH CORP
摘要:Disclosed herein are compounds that selectively inhibit members of the PTP family of enzymes. Synthesized compounds demonstrated selective inhibition of TC-PTP. Also provided are methods of using the compounds and formulations containing the compounds. Also described is a fluorescence-tagged combinatorial library synthesis and screening method. And methods of using these compounds to effect enzyme activity both in cells and in vitro as well as method of using these compounds to treat diseases in human and animals.
四川同晟生物医药有限公司
⚠️ 未注册 · 未认证企业
⚠️ 该商家尚未完成注册及企业认证,请用户仔细辨别,谨慎交易。
数据来源于公开网络搜索,平台未作核实,请自行辨别。
🏢敬请 企业认领
🏬开设公司展台
📢获取免费会员权益
🎖️点亮专属注册企业标签
📇展现公司完整信息 样本查看立即注册认领 →
网址: http://www.biots.cn
企业联系电话:0838-2809458/13350585791👤
📞四川同晟生物医药有限公司 ⚠️参考联系方式
联系人:赵佳
电话:0838-2809458/13350585791
手机:13350585791
传真:0838-2809448
邮箱:pharm@biots.cn
通信地址: 德阳市旌阳区天元镇武庙村
邮编: 618000
🆔 联系时候可告知是从"百琢研"平台获取的信息.
⚠️ 声明: 该企业未认证、未认领,请自行辨别信息的真实性和可靠性。咨询或交易时请注意风险评估与信息核实,百琢研不参与任何交易。企业认领注册入口→

地址:德阳市旌阳区天元镇武庙村
⚠️ 未注册 · 未认证企业
注册入口 备注: 📌 数据来源说明:本展台内容基于各搜索引擎等公开数据整理,仅作展示用途。请用户自行辨别
✉️ 若企业需抹除展台内容或有异议, 请通过页面底部联系方式告知我们,我们会尽快处理。
第 1 / 1 页

供应商参考报价(招募中)

品牌试剂参考报价(招募中)

📌 第三方产品分析报告

✅ COA系统入驻 | 共享模式

合成参考文献


摘要:Aitken, R. A.; Meehan, A., Science of Synthesis Knowledge Updates, (2014) 3, 149.
参考文献:10.1007/bf02478922
摘要:Uematsu Y, Tanaka Y, Shimizu M, Oobayashi S, Fujita K, Nakai K, Itakura T, Moriwaki H, Kamei I. Histogenesis and proliferative activity of central neurocytomas. Brain Tumor Pathol. 2001;18(1):29–36. doi: 10.1007/bf02478922.
参考文献:10.1023/a:1014880403970
摘要:Leal RB, Sim AT, Gonçalves CA, Dunkley PR. Tyrosine hydroxylase dephosphorylation by protein phosphatase 2A in bovine adrenal chromaffin cells. Neurochem Res. 2002 Mar;27(3):207–13. doi: 10.1023/a:1014880403970.
参考文献:10.1007/978-1-61779-126-0_7
摘要:Davey J, Ladds G. Heterologous expression of GPCRs in fission yeast. Methods Mol Biol. 2011;746():113–31. doi: 10.1007/978-1-61779-126-0_7.
参考文献:10.1023/b:cbto.0000004975.36521.c8
摘要:Chadebech P, Goidin D, Jacquet C, Viac J, Schmitt D, Staquet MJ. Use of human reconstructed epidermis to analyze the regulation of beta-defensin hBD-1, hBD-2, and hBD-3 expression in response to LPS. Cell Biol Toxicol. 2003 Oct;19(5):313–24. doi: 10.1023/b:cbto.0000004975.36521.c8.
📝 需求与反馈
尽可能描述清楚需求与问题信息
×

通知