CAS: 1530-45-6; (2-Ethoxy-2-Oxoethyl)Triphenylphosphonium Bromide

相似化合物

17577-28-5 7237-34-5 23250-03-5

上下游产品

CAS号105-36-2 溴乙酸乙酯 | CAS号603-35-0 三苯基膦 | CAS号39219-88-0 4-(4'-fluorophe... | CAS号1099-45-2 乙基(三苯基膦)乙酸酯 | CAS号1685-97-8 1H-Indene-1,3(2... | CAS号134898-35-4 (1-(2-bromo-1,3... | CAS号16619-55-9 2,2-二溴-1,3-二苯基-... | CAS号134898-26-3 (3-benzoyl-3-br... | CAS号17577-28-5 (乙氧基羰基甲基)三苯基氯化膦 | CAS号623-73-4 重氮乙酸乙酯 | CAS号111598-99-3 (2-ethoxy-1-iod... | CAS号14731-78-3 2-Propenoic aci... | CAS号201221-74-1 ethyl 2-iodo-3-... | CAS号93-35-6 伞形花内酯； 7-羟基香豆素 | CAS号20583-78-2 3-(3,4-二甲氧基苯基)丙烯酸乙酯 | CAS号614-60-8 2-羟基肉桂酸; 邻羟基肉桂酸 | CAS号131375-80-9 benzyl hex-2-enoate | CAS号15898-67-6 diethyl nona-2,... | CAS号1099-45-2 乙基(三苯基膦)乙酸酯

溴乙酸乙酯置于三苯基膦体系中,用 苯 用作溶剂,以95%的收率获得乙氧甲酰基甲基三苯基溴化膦
参考文献:Triphenylphosphine-Catalyzed [3+2] Cycloaddition Of Allenoate And Active Olefins: Syntheses Of Spirooxindole Derivatives
标题:Triphenylphosphine-Catalyzed [3+2] Cycloaddition Of Allenoate And Active Olefins: Syntheses Of Spirooxindole Derivatives
摘要:通过三苯基膦催化的[3+2]环加成反应,成功合成了一系列螺旋化合物,反应物为活性亚甲基马隆腈和乙基2,3-丁二烯酸酯.细致的研究表明,该方法具有较高的区域选择性.产物呈现出螺氧吲哚骨架,这是一种在许多自然产物和药效活性化合物中常见的结构特征.
Doi:10.1055/s-0030-1261188

专利信息

专利号:WO-2024220193-A1
优先权日:2023-04-21
标题 :Methods for preparing (-)-epicatechin
发明人：PAIS GODWIN
权利人:MARS INC
摘要:Methods steps for the synthesis of (-)-epicatechin are provided herein. The synthetic methods are provided in two phases: (1) synthesis of epoxide intermediates and (2) synthesis of (-)-epicatechin.

专利号:US-9994558-B2
优先权日:2013-09-20
标题 :Multicyclic compounds and methods of using same
发明人：BALOGLU ERKAN; SHACHAM SHARON; SENAPEDIS WILLIAM; MCCAULEY DILARA; LANDESMAN YOSEF; GOLAN GALI; KALID ORI; SHECHTER SHARON
权利人:KARYOPHARM THERAPEUTICS INC
摘要:The invention generally relates to compounds represented by Structural Formula I: or a pharmaceutically acceptable salt thereof, wherein the variables are as defined and described herein. The invention also includes the synthesis and use of a compound of structural formula I, or a pharmaceutically acceptable salt or composition thereof, e.g., in treatment of cancer (e.g., mantle cell lymphoma), and other diseases and disorders (e.g., PAK-mediated, for example, PAK4-mediated, diseases and disorders).

专利号:US-4603209-A
优先权日:1984-09-07
标题 :Fluorescent indicator dyes for calcium ions
发明人：TSIEN ROGER Y; GRYNKIEWICZ GRZEGORZ
权利人:UNIV CALIFORNIA
摘要:The present invention discloses a new class of highly fluorescent indicator dyes that are specific for calcium ions. The new fluorescent indicator dyes combine a stilbene-type fluorophore with a tetracarboxylate parent Ca 2+ chelating compound having the octacoordinate pattern of liganding groups characteristic of EGTA and BAPTA. Preferred forms contain extra heterocyclic bridges to reinforce the ethylenic bond of the stilbene and to reduce hydrophobicity. Compared to their widely used predecessor, 'quin2', the new dyes offer up to thirty-fold brighter fluorescence, major changes in wavelength (not just intensity) upon Ca 2+ binding, slightly lower affinities for Ca 2+ , slightly longer wavelengths of excitation, and considerably improved selectivity for Ca 2+ over other divalent cations. These properties, particularly the wavelength sensitivity to Ca 2+ , make the dyes useful indicators for many intracellular applications, especially in single cells, adherent cell layers, or bulk tissues. n The present invention also discloses an improved method for synthesizing alpha-acyloxyalkyl bromides wherein the bromides so synthesized are free of contaminating bis(1-bromoalkyl)ether. The improved method is exemplified herein in the synthesis of acetoxymethyl bromide, a compound useful in preparing the acetoxymethyl esters disclosed herein as novel Ca 2+ specific fluorescent indicators.

专利号:US-9950067-B2
优先权日:2005-02-24
标题:Trans carotenoids, their synthesis, formulation and uses
发明人：GAINER JOHN L; LANZ MARC
权利人:DIFFUSION PHARMACEUTICALS LLC
摘要:The invention relates to trans carotenoid compounds and salts thereof as well as compositions thereof, methods for making them, and uses thereof. These compounds are useful in improving diffusivity of oxygen between red blood cells and body tissues in mammals including humans.

专利号:US-9938258-B2
优先权日:2012-11-29
标 题:Substituted 2,3-dihydrobenzofuranyl compounds and uses thereof
发明人：BALOGLU ERKAN; SHECHTER SHARON; SHACHAM SHARON; MCCAULEY DILARA; SENAPEDIS WILLIAM; GOLAN GALI; KALID ORI
权利人:KARYOPHARM THERAPEUTICS INC
摘要:The invention generally relates to substituted 2,3-dihydrobenzofuranyl compounds, and more particularly to a compound represented by Structural Formula I: n nor a pharmaceutically acceptable salt thereof, wherein the variables are as defined and described herein. The invention also includes the synthesis and use of a compound of Structural Formula I, or a pharmaceutically acceptable salt or composition thereof, e.g., in the treatment of cancer (e.g., mantle cell lymphoma), and other diseases and disorders.

专利号:US-2008280886-A1
优先权日:2007-05-08
标题:Substituted ureas
发明人：GANT THOMAS G; SARSHAR SEPEHR
权利人:AUSPEX PHARMACEUTICALS INC
摘要:Disclosed herein are urea-based 5-HT receptor modulators, pharmaceutically acceptable salts and prodrugs thereof, the chemical synthesis thereof, and medical use of such compounds for the treatment and/or management of 5-HT receptor-mediated disorders.