专利号:WO-2017175101-A1 优先权日:2016-04-07 标 题:Synthesis of copper phthalocyanine using deep eutectic solvent 发明人:SHANKARLING G S; JOGLEKAR AMRUTA R 权利人:SHANKARLING G S 摘要:The present disclosure generally relates to synthesis of copper phthalocyanine. In particular, the present disclosure relates to a method of synthesis of copper phthalocyanine using deep eutectic solvent (DES), which can be carried out at low temperature, does not involve use of high boiling solvents, uses less urea and allows solvents used in the process to be recycled.
专利号:US-11897860-B2 优先权日:2022-03-14 标题 :Direct synthesis of cyclic carbonates using choline chloride as catalyst under mild conditions 发明人:CARRASCO ANALETTE; WEERS JERRY J; BLACKWELL CATHERINE C; MURUGESAN SANKARAN; WANG XIAOFENG; NUGENT DOUGLAS; ROBERTS CORBY A 权利人:BAKER HUGHES OILFIELD OPERATIONS LLC 摘要:A method for direct synthesis of cyclic carbonates is achieved by reacting at least one epoxide with carbon dioxide in the presence of a choline catalyst, such as choline chloride, under mild conditions such as a temperature between about 25° C. to 150° C. and a pressure of from about atmospheric to 75 psi (0.52 MPa), in a cyclic carbonate solvent. The choline catalyst may be the only catalyst used, and a co-catalyst or hydrogen bond donor is not necessary. The concentration of choline catalyst in the solvent ranges from about 0.5 mol % to about 10 mol %, based on the epoxide.
专利号:WO-2025109557-A1 优先权日:2023-11-24 标题:Process for the synthesis of monoesters of ethylenediaminetetraacetic acid 发明人:TERAZONO YUICHI 权利人:NUTRIEN AG SOLUTIONS CANADA INC 摘要:A process for the synthesis of a compound of Formula (I) is provided. (I) wherein R is selected from the group consisting of alkyl, alkenyl, alkynyl, and steroidyl. The process comprises reacting a compound of Formula (IIa), Formula (IIb) or a mixture thereof with a compound of Formula R-X, to obtain a compound of Formula (IIIa), a compound of Formula (IIIb) or a mixture thereof, wherein A+ is a cesium cation, a quaternary ammonium cation or a quaternary phosphonium cation, and X is a leaving group; and reacting the compound of Formula (IIIa), compound of Formula (IIIb) or mixture thereof with an acid to obtain a reaction product which comprises the compound of Formula (I). (IIa) (IIb) (IIIa) (IIIb)
专利号:US-12391691-B2 优先权日:2018-11-16 标题:Synthesis of key intermediate of KRAS G12C inhibitor compound 发明人:PARSONS ANDREW THOMAS; COCHRAN BRIAN MCNEIL; POWAZINIK IV WILLIAM; CAPORINI MARC ANTHONY 权利人:AMGEN INC 摘要:The present invention relates to an improved, efficient, scalable process to prepare intermediate compounds, such as compound 5M, having the structure n nuseful for the synthesis of compounds that target KRAS G12C mutations, such as
专利号:US-2025206736-A1 优先权日:2019-11-14 标题 :Synthesis of kras g12c inhibitor compound 发明人:CORBETT MICHAEL THOMAS; CAILLE SEBASTIEN 权利人:AMGEN INC 摘要:The present disclosure relates to an improved, efficient, scalable process to prepare intermediate compounds, such as 2-isopropyl-4-methylpyridin-3-amine, useful for the synthesis of compounds, such as Compound 9, for the treatment of KRAS G12C mutated cancers.
专利号:US-11136302-B2 优先权日:2017-05-26 标 题:Single step process for the synthesis of furan derivatives from carbohydrates 发明人:RODE CHANDRASHEKHAR VASANT; SHINDE SUHAS HANMANT 权利人:COUNCIL SCIENT IND RES 摘要:The present invention discloses a single step process for the synthesis of furan derivative from carbohydrate comprises stirring the reaction mixture of carbohydrate in solvent in presence of catalyst at temperature in the range of 170 to 190° C. for the period in the range of 23 to 25 hrs to afford corresponding furan derivative.
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合成参考文献
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