专利号:US-7312250-B2 优先权日:2002-03-12 标题 :Fluorine-substituted alkyl phenol compounds and their uses 发明人:BAKER MAX T; NAGUIB MOHAMED 权利人:UNIV IOWA RES FOUND 摘要:The present invention relates to the synthesis of fluorinated forms of alkyl phenol compounds and their subsequent use as pharmaceutical agents. More specifically, alkyl phenol compounds are fluorinated to increase compound volatility such that the compound may be administered to a mammal, such as a human being, by inhalation. The invention also provides an inhaler (or vaporizer), that can be used for administration of the volatile derivatives of fluorine-substituted alkyl phenol compound. Further, different derivatives of fluorine-substituted alkyl phenol compound can be also administered by other routes as described in this document.
专利号:US-6093805-A 优先权日:1991-01-22 标 题:Glycoside compounds and methods of synthesis 发明人:SHULL BRIAN K; TUINMAN ROELAND J; HOUSTON TODD A; KLEMKE R ERICH; KOREEDA MASATO 权利人:UNIV MICHIGAN 摘要:Novel glycosides, especially steroidal and non-steroidal glycosides are provided. The steroidal and non-steroidal glycosides preferably are prepared from aglycons which possess valuable properties such as pharmacological properties. The glycosides are prepared from useful aglycons and possess useful properties which are the same as those of their respective unglycosylated aglycons. The glycosides are provided in acylated and deacylated form. The acylated glycosides after hydrolysis of the acyl groups possess enhanced water solubility properties, as illustrated in the case where the aglycon is acetominophen.
专利号:US-4272507-A 优先权日:1978-05-24 标 题:Phenylaminothiophenacetic acids, their synthesis, compositions and use 发明人:FIGALA VOLKER 权利人:BYK GULDEN LOMBERG CHEM FAB 摘要:Phenylaminothiophenacetic acids of formula I (I) wherein R1 denotes a hydrogen atom, a chlorine atom, a bromine atom or a methyl group, R2 denotes a -CH2-COOH group or a -CH2-COOR6 group, R3 denotes a hydrogen atom, a halogen atom, an alkyl group, an alkoxy group or a trifluoromethyl group, R4 has one of the meanings of R3, R5 denotes a hydrogen atom, a halogen atom or an alkyl group, R6 denotes an alkyl group (with from 1 to 5 carbon atoms), which is optionally substituted by hydroxyl, hydroxyalkoxy or alkanoyloxy groups, or a benzyl group and n denotes 1 or 2, and salts of the acids have outstanding antiphlogistic, analgesic and antipyretic activities.
专利号:CN-101980950-A 优先权日:2008-02-07 标 题:Shear reactor for vortex synthesis of nanotubes
专利号:CN-1073934-A 优先权日:1991-08-23 标题 :A New Method for the Synthesis of 2-Hydroxy Aromatic Aldehydes
专利号:CN-110483289-A 优先权日:2019-07-31 标题 :A kind of method for asymmetric synthesis of chiral alkenoate
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