CAS: 75-96-7; Tribromoacetic Acid

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CAS号76-03-9 三氯乙酸 | CAS号79-28-7 四溴乙烯 | CAS号115-17-3 三溴乙醛 | CAS号141-82-2 丙二酸 | CAS号10588-31-5 tribromoacetic ... | CAS号64-19-7 冰醋酸 | CAS号107-38-0 胂羧基乙酸 | CAS号75-25-2 三溴甲烷 | CAS号124-38-9 二氧化碳 | CAS号79-21-0 过氧乙酸 | CAS号354-49-4 1,1,2-三溴三氟乙烷 | CAS号7726-95-6 溴素 | CAS号10035-10-6 氢溴酸 | CAS号949-97-3 1-Benzylglycero... | CAS号75-25-2 三溴甲烷 | CAS号124-38-9 二氧化碳 | CAS号2909-52-6 三溴甲烷 | CAS号594-73-0 六溴乙烷 | CAS号631-64-1 二溴乙酸

四溴乙烯置于氧气,水体系中,化学反应 102.0H,以13.8 G的收率获得产物三溴乙酸
参考文献:Liquid-Phase Oxidation Of Bromovinyl Compounds With Molecular Oxygen
标题:Liquid-Phase Oxidation Of Bromovinyl Compounds With Molecular Oxygen
摘要:Liquid-Phase Oxidation Of Bromovinyl Compounds With The Aim To Obtain The Corresponding (X-Bromo Acids Was Studied.
DOI:10.1134/s1070427206110218

专利信息

专利号:US-11680224-B2
优先权日:2020-11-04
标 题:Hydroxy fatty acid synthesis
发明人：CERMAK STEVEN C; Isbell Terry; LOWERY BENJAMIN A
权利人:US AGRICULTURE; THE US SECRATERY OF AGRICULTURE
摘要:The invention relates to methods for the synthesis of hydroxy fatty acids from unsaturated fatty acids via epoxidation and catalytic hydrogenation.

专利号:US-11738092-B2
优先权日:2019-12-04
标题:Methods and compositions for synthesis of therapeutic nanoparticles
发明人：WYENT EMILY A; BLUMENFELD CARL M; LAMM ROBERT J
权利人:DANTARI INC
摘要:Improved methods and reactants for the chemical synthesis of therapeutic nanoparticles are provided. The nanoparticles comprise a polymeric core, to which is attached one or more homing molecules and one or more therapeutic agents. Improvements in speed, yield and purity are attained using the methods disclosed herein.

专利号:WO-2025132814-A1
优先权日:2023-12-21
标 题:Novel synthesis of methyl-2-fluoroacrylate
发明人：BRUNKE JESSICA; FISCHER MICHAEL; WÖSSNER JAN STEPHAN
权利人:VIFOR INT AG
摘要:The present invention relates to novel synthesis methods of methyl 2-fluoroacrylate (MFA) which is a key precursor for the production of Veltassa® (Patiromer). The methods according to the invention are conducted by reacting an α-substituted β-hydroxy propionic acid derivative (I) via one or more intermediate steps involving one or more α-, β-substituted propionic acid derivatives (II) to obtain MFA (III).

专利号:US-8927739-B2
优先权日:2011-05-18
标 题 :Processes for the preparation of 5-azaspiro[2.4]heptane-6-carboxylic acid and its derivatives
发明人：QIU YAO-LING; PENG XIAOWEN; KIM IN JONG; CAO HUI; TANG DATONG; OR YAT SUN; WANG GUOQIANG; XU GUOYOU
权利人:ENANTA PHARM INC
摘要:The present invention relates generally to an improved process for the preparation of 5-azaspiro[2.4]heptane-6-carboxylic acid and its derivatives which are useful intermediates in the synthesis of biologically active molecules, especially in the synthesis of hepatits C virus NS5A inhibitors. In particular, the present invention relates to processes and intermediates for the preparation of compounds of formulae (Ia), (Ib) and (Ic):

专利号:US-6288297-B1
优先权日:1998-10-01
标 题:Process for the preparation of cyclopropylacetylene
发明人：WANG ZHE; YIN JIANGUO; FORTUNAK JOSEPH M; CAMPAGNA SILVIO
权利人:DU PONT PHARM CO
摘要:The present invention relates generally to novel methods for the synthesis of cyclopropylacetylene which is an essential reagent in the asymmetric synthesis of (S)-6-chloro-4-cyclopropylethynyl-4-trifluoromethyl-1,4-dihydro-2H-3,1-benzoxazin-2-one; a useful human immunodeficiency virus (HIV) reverse transcriptase inhibitor. In the process, for example, cyclopropane carboxaldehyde is alkylated to form 1,1,1-trichloro-2-cyclopropyl-ethanol; which in turn is hydroxy protected to form 1,1,1-trichloro-2-cyclopropylethyltosylate; which in turn undergoes elimination to form cyclopropyl acetylene. This improvement provides for high conversion of inexpensive, readily available starting materials into cyclopropylacetylene, high overall yields and can be conducted on an industrial scale.

专利号:US-2007015798-A1
优先权日:2005-02-25
标 题 :Efficient and stereoselective process for large scale synthesis of (3R)-3-(2,3-dihydrobenzofuran-5-yl)-1,2,3,4-tetrahydropyrrolo[3,4-b]quinolin-9-one derivatives
发明人：LI XUN; LEMAIRE SEBASTIEN; MARKO ISTVAN; WILLEMSENS ALBERT
权利人:LI XUN; LEMAIRE SEBASTIEN; MARKO ISTVAN; WILLEMSENS ALBERT
摘要:This invention relates to an efficient process for large scale stereoselective production of (3R)-3-(2,3-dihydrobenzofuran-5-yl)-1,2,3,4-tetrahydropyrrolo[3,4-b]quinolin-9-ones and key intermediates used for the preparation of benzofuranyl pyrroloquinolones as potent and selective PDE5 inhibitors for the treatment of erectile dysfunction, as well as pharmaceutical compositions and methods of treatment utilizing these compounds.