对硝基氯苯置于氯磺酸体系中,化学反应 18.0H,反应生成 2-氯-5-硝基苯磺酸 参考文献:Methods And Compounds For Treating Proliferative Disorders And Viral Infections 标题:Methods And Compounds For Treating Proliferative Disorders And Viral Infections 摘要:这项发明通常涉及用于治疗增殖性疾病,病毒感染或两者的方法和化合物.在某些实施例中,该发明提供了一种抗癌或抗病毒化合物,包括一种取代硝基苯氧基苯基,磺酰脲和烷基.在某些实施例中,该发明提供了一种治疗增殖性疾病或病毒感染的方法,包括给予一种结合到血栓素a2受体,对tpalpha(tpα)或tpbeta(tpβ)受体亚型具有优先结合的抗癌或抗病毒化合物.
专利号:US-4895954-A 优先权日:1986-07-26 标题 :Precursors for synthesis of triphendioxazine dyestuffs 发明人:SCHWAIGER GUENTHER; SPRINGER HARTMUT; HELMLING WALTER 权利人:HOECHST AG 摘要:Water-soluble triphendioxazine compounds which have fiber-reactive properties as dyestuffs, which afford deep and fast dyeings on fiber materials, such as wool and, in particular, cellulose, and which correspond to the formula (1) ##STR1## in which: n is the number 0 or 1; n Y is the vinyl group or an ethyl group containing, in β-position, a substituent which can be eliminated by means of an alkali; n Q 1 and Q 2 both represent a benzotriazole radical which can also be additionally substituted in the benzene nucleus by alkyl having 1 to 4 carbon atoms, alkoxy having 1 to 4 carbon atoms, halogen, carboxy or sulfo; n B is --O--, --S--, --NH-- or --N(R')-- wherein R' is optionally substituted alkyl having 1 to 6 carbon atoms; n W 1 and W 2 both represent a divalent, optionally substituted aliphatic, cycloaliphatic, aliphatic-cycloaliphatic, araliphatic or aromatic-carbocyclic radical, it being possible for the aliphatic radicals to be interrupted by hetero groups --O--, --S--, --SO 2 --, --CO--, 1,4-piperidino, --NH-- and/or --N(R o )-- in which R o is optionally substituted alkyl having 1 to 6 carbon atoms or alkanoyl having 2 to 5 carbon atoms, and/or for aliphatic and aryl radicals to be attached to one another through such a hetero group; n R is hydrogen, alkyl having 1 to 6 carbon atoms, alkoxy having 1 to 6 carbon atoms, halogen, carboxyl or sulfo; n E is hydrogen, sulfo, carboxyl, a group --SO 2 --Y as defined above or an optionally substituted sulfonamide group; and n X 1 and X 2 are both hydrogen or halogen, cycloalkyl, alkoxy, aryloxy, aryl or another substituent; n and at least one carboxy, sulfo or sulfato group is present in the molecule (1), n and pre-products of those triphendioxazine compounds, of the general formula ##STR2## in which K is an amino or nitro group, Y' is β-hydroxyethyl or defined as for Y, W has one of the meanings of W 1 , and E' is hydrogen, sulfo, carboxy or a group of the formula --SO 2 --Y' defined above, or an optionally substituted sulfonamide group, and R, B and R* have the above meanings.
专利号:US-4093812-A 优先权日:1975-03-25 标 题:(Nitrofuryl)pyrazoles, their synthesis and use, and compositions containing them 发明人:RAINER GEORG 权利人:BYK GULDEN LOMBERG CHEM FAB 摘要:3-(5-Nitro-2-furyl)pyrazoles unsubstituted in the 5-position and 5-(5-nitro-2-furyl)pyrazoles unsubstituted in the 3-position are antimicrobials and disinfectants. The compounds are structurally represented by one of the formulae: ##STR1## wherein A is --CHO, --CN, --COOH, a protected or derived aldehyde group or a protected or derived carboxylic acid group; n B is 5-nitro-2-furyl; n R 1 is --H, substituted or unsubstituted hydrocarbyl (saturated or unsaturated; acyclic, alicyclic or aromatic; or araliphatic); substituted or unsubstituted (cycloaliphatic or aromatic) heterocyclic or acyl (carboxylic or carbonic acid); n R 2 is --H; and n n is a positive whole number of at most 2.
专利号:CN-102351751-A 优先权日:2011-08-12 标题:A kind of chemical synthesis method of 5-nitro-2-chlorobenzenesulfonyl chloride
专利号:CN-115873419-A 优先权日:2022-12-30 标 题:A kind of reactive dye synthesis method and its application
参考文献:10.1007/bf00325571 摘要:Bastian B, Knepper TP, Hoffmann P, Ortner HM. Determination of aromatic sulfonic acids in industrial waste water by ion-pair chromatography. Analytical and Bioanalytical Chemistry. 1994 Oct;348(10):674–9. doi: 10.1007/bf00325571. 参考文献:10.1007/bf02991058 摘要:Golan-Goldhirsh A, Barazani O, Nepovim A, Soudek P, Smrcek S, Dufkova L, Krenkova S, Yrjala K, Schröder P, Vanek T. Plant response to heavy metals and organic pollutants in cell culture and at whole plant level. Journal of Soils and Sediments. 2004 Jun;4(2):133–40. doi: 10.1007/bf02991058.