CAS: 121-33-5; 4-Hydroxy-3-Methoxybenzaldehyde

相似化合物

121-34-6 3943-74-6 498-00-0

上下游产品

CAS号120-14-9 藜芦醛； 3,4-二甲氧基苯甲醛 | CAS号93-51-6 2-甲氧基-4-甲基苯酚 | CAS号69404-94-0 4-[tert-butyl(d... | CAS号5932-68-3 (E)-2-甲氧基-4-(1-... | CAS号91471-08-8 3-methoxy-4-[(t... | CAS号67-56-1 甲醇 | CAS号498-00-0 香草醇 | CAS号5533-00-6 3-methoxy-4-(me... | CAS号97-54-1 异丁香酚(正+反) | CAS号109322-03-4 2-(2-chloroindo... | CAS号107788-00-1 (E)-2-cyano-3-[... | CAS号107044-96-2 N'-[(Z)-(3-meth... | CAS号106174-97-4 1-(4-hydroxy-3-... | CAS号104202-36-0 2,4-dimethoxy-1... | CAS号110642-42-7 (E)-5-Hydroxyfe... | CAS号33693-48-0 4-苄氧基-3-甲氧基苯甲醇 | CAS号52783-83-2 4-乙酰氧基-2-溴-5-甲氧基苯甲醛 | CAS号32024-15-0 4,5-二甲氧基-3-碘苯甲醛 | CAS号34098-18-5 3-氯-4,5-二羟基苯甲醛

2-Methoxy-4-Spiro[1,3-Dioxane-5,5'-Bicyclo[2.2.1]Hept-2-Ene]-2-Ylphenol置于silica-Oso3H,Silica Gel体系中,用 甲苯 用作溶剂,化学反应 1.0H,以97%的收率获得香草醛
参考文献:用二氧化硅硫酸和湿 Sio2 脱保护缩醛和缩酮
标题:用二氧化硅硫酸和湿 Sio2 脱保护缩醛和缩酮
摘要:纯氯磺酸与硅胶反应生成二氧化硅硫酸,其中硫酸通过共价键固定在硅胶表面.二氧化硅硫酸和湿 Sio2 的组合被用作有效的脱缩醛剂,用于在热条件下将缩醛转化为其相应的羰基衍生物.
Doi:10.3390/71000751

专利信息

专利号:US-10308588-B2
优先权日:2014-12-15
标 题 :Synthesis of amides and amines from aldehydes or ketones by heterogeneous metal catalysis
发明人：CÓRDOVA ARMANDO; PALO-NIETO CARLOS; AFEWERKI SAMSON
权利人:ORGANOFUEL SWEDEN AB
摘要:A mild and efficient synthesis of primary amines and amides from aldehydes or ketones using a heterogeneous metal catalyst and amine donor is disclosed. The initial heterogeneous metal-catalyzed reaction between the carbonyl and the amine donor components is followed by the addition of a suitable acylating agent component in one-pot, thus providing a catalytic one-pot three-component synthesis of amides. Integration of enzyme catalysis allows for eco-friendly one-pot co-catalytic synthesis of amides from aldehyde and ketone substrates, respectively. The process can be applied to asymmetric synthesis or to the co-catalytic one-pot three-component synthesis of capsaicin and its analogues from vanillin or vanillyl alcohol. A co-catalytic reductive amination/dynamic kinetic resolution (dkr) relay sequence for the asymmetric synthesis of optically active amides from ketones is disclosed. Implementation of a catalytic reductive amination/kinetic resolution (kr) relay sequence produces the corresponding optically active amide product and optical active primary amine product with the opposite stereochemistry from the starting ketones.

专利号:US-2008032964-A1
优先权日:2006-04-10
标题:Process for the synthesis of azetidinone
发明人：KANSAL VINOD K; AHMAD SUHAIL; MARIAPPAN SHANMUGAVEL; TYAGI BHUPENDRA; PERLMAN NURIT; LE PAIH JACQUES; ZANOTTI-GEROSA ANTONIO
权利人:KANSAL VINOD K; AHMAD SUHAIL; MARIAPPAN SHANMUGAVEL; TYAGI BHUPENDRA; PERLMAN NURIT; LE PAIH JACQUES; ZANOTTI-GEROSA ANTONIO
摘要:Provided are intermediates useful for the synthesis of hydroxyl-alkyl substituted azetidinones, processes of their preparation, and processes for the synthesis of certain hydroxyl-alkyl substituted azetidinones. Also provided are processes for the synthesis of 1-(4-fluorophenyl)-3(R)-[3-(4-fluorophenyl)-3(S)-hydroxypropyl]-4(S)-(4-hydroxyphenyl)-2-azetidinone, or ezetimibe.

专利号:WO-2024153752-A1
优先权日:2023-01-20
标 题 :Stereoselective synthesis of intermediates and synthesis of quinagolids
发明人：RYBERG PER; PINESCHI MAURO; COMPARINI LUCREZIA
权利人:FERRING BV
摘要:Disclosed is a method for preparing compounds with improved stereoselectivities. The described compounds are useful intermediates and may find particular application in the synthesis of compounds containing an octahydrobenzoquinoline moiety (e.g. an octahydrobenzo[g]quinoline moiety), such as quinagolide and its derivatives. Also disclosed is a method for stereoselectively (e.g. enantioselectively) preparing an intermediate used in the existing manufacturing process for the synthesis of quinagolide this intermediate also finding utility in the synthesis of other compounds containing an octahydrobenzo[g]quinoline moiety, in particular those having a substituent at the 3- position on the octahydrobenzo[g]quinoline.

专利号:US-5861532-A
优先权日:1997-03-04
标 题:Solid-phase synthesis of N-alkyl amides
发明人：BROWN EDWARD G; NUSS JOHN M
权利人:CHIRON CORP
摘要:Methods for solid phase synthesis of N-alkyl amides comprise reductive amination of carbonyl compounds using a reducing agent and an amine-containing linker bound to a solid support. The methods afford high yields of linker-bound, monoalkylated amines, and subsequent coupling with acid derivatives provide derivatized N-substituted amides in excellent yields after cleavage from the solid-phase. Compositions useful in solid phase synthesis are also described.

专利号:US-12344881-B2
优先权日:2023-09-27
标题 :Genetic engineering bacterium for de novo synthesis of cis,cis-muconic acid by taking glucose as substrate and applications thereof
发明人：TAN TIANWEI; LI MENGLEI
权利人:UNIV BEIJING CHEM TECH
摘要:The present invention discloses a genetic engineering bacterium for de novo synthesis of cis,cis-muconic acid by taking glucose as a substrate and applications thereof, and belongs to the technical field of genetic recombination and metabolic engineering. The genetic engineering bacterium for de novo synthesis of cis,cis-muconic acid (MA) by taking glucose as the substrate disclosed in the present invention is modified with chassis microbes, and includes recombinant Corynebacterium glutamicum for a cis,cis-muconic acid pathway construction module and an intermediate high-yield module. Production capacity of strains is greatly improved; MA of 90.2 g/L is finally obtained in fermentation liquor; and possibilities are provided for green and low-cost production of numerous chemicals such as adipic acid and nylon-66.

专利号:US-11220513-B2
优先权日:2015-04-30
标题:Chromium-mediated coupling and application to the synthesis of halichondrins
发明人：KISHI YOSHITO; YAN WUMING; LI JINGWEI; LI ZHANJIE; YAHATA KENZO
权利人:HARVARD COLLEGE
摘要:The present invention provides unified synthesis of the C1-C19 building blocks of halichondrins and analogs thereof using selective coupling of poly-halogenated nucleophiles in chromium-mediated coupling reactions. The present invention also provides a practical and efficient synthesis of C20-C38 building blocks of halichondrins and analogs thereof. Also provided herein are general methods of selective activation and coupling of poly-halogenated analogs with an aldehyde. The provided coupling reactions are selective for halo-enone and halo-acetylenic ketal over vinyl halide and halide attached to a sp hybridized carbon. The provided efficient selective coupling reactions can allow easy access to the C1-C19 building blocks and C20-C38 building blocks of halichondrins and analogs thereof with limited or no purification or separation of the intermediates.