CAS: 17874-79-2; 5-(Methoxycarbonyl)Picolinic Acid

相似化合物

6221-01-8 40749-33-5 53574-58-6

上下游产品

CAS号881-86-7 2,5-吡啶-二羧酸二甲酯 | CAS号100-26-5 吡啶-2,5-二羧酸 | CAS号7377-26-6 4-氯甲酰基苯甲酸甲酯 | CAS号169124-35-0 6-(氯羰基)烟酸甲酯 | CAS号153559-92-3 6-(3,5,5,8,8-PE... | CAS号153559-44-5 6-[(3,5,5,8,8-P... | CAS号153559-50-3 METHYL 6-(1-(1,... | CAS号39977-41-8 5-羟基甲基-吡啶-2-羧酸

2,5-二吡啶羧酸置于甲醇,Sodium Hydroxide,硫酸体系中,化学反应 21.0H,反应生成5-(甲氧羰基)-2-吡啶羧酸
参考文献:Conjugates Of Artemisinin-Related Endoperoxides And Hydrazone Derivatives For The Treatment Of Cancer
标题:Conjugates Of Artemisinin-Related Endoperoxides And Hydrazone Derivatives For The Treatment Of Cancer
摘要:具有与联接剂通过连接剂共价耦合的肟基的青蒿素相关内过氧化物基团的化合物.使用这些化合物治疗癌症的组合物和方法.

专利信息

专利号:US-8012972-B2
优先权日:2007-03-28
标 题:Pyridinecarboxylic acid (2-aminophenyl) amide derivative having urea structure
发明人：MOGI HIROYUKI; TAJIMA HISASHI; MISHINA NORIKO; YAMAZAKI YUSUKE; YONEDA SHINJI; WATANABE KATSUHIKO; FUJIKAWA JUNKO; YAMAMOTO MINORU
权利人:SANTEN PHARMACEUTICAL CO LTD
摘要:Objects of the present invention are to study the synthesis of a novel pyridinecarboxylic acid (2-aminophenyl)amide derivative having a novel urea structure and to find a pharmacological effect of the derivative. The invention provides a compound represented by the formula (1) or a salt thereof. In the formula, R 1 and R 2 represent a hydrogen atom, a lower alkyl group or the like; R 3 represents a hydroxy group, a lower alkoxy group, a lower cycloalkyloxy group, an aryloxy group, a carboxy group, a lower alkoxycarbonyl group, —OCONR a R b , —NR c R d or the like; R 4 and R 5 represent a halogen atom, a lower alkyl group, a hydroxy group, a lower alkoxy group or the like; R a and R b represent a hydrogen atom, a lower alkyl group, a lower cycloalkyl group, an aryl group, a heterocyclic group or the like; R c and R d represent a hydrogen atom, a lower alkyl group, a lower cycloalkyl group, an aryl group or the like; X represents a lower alkylene group; Y represents a single bond, a lower alkylene group; W 1 -W 2 represents N—C or C—N; and l and m represent 0, 1, 2 or 3.

专利号:US-2010152208-A1
优先权日:2007-05-23
标 题:Bicyclic heteroaromatic compounds as inhibitors of stearoyl-coenzyme a delta-9 desaturase
发明人：LEGER SERGE; DESCHENES DENIS; FORTIN REJEAN; ISABEL ELISE; POWELL DAVID
权利人:MERCK FROSST CANADA LTD
摘要:Bicyclic heteroaromatic compounds of structural formula I are inhibitors of stearoyl-coenzyme A delta-9 desaturase (SCD). The compounds of the present invention are useful for the prevention and treatment of conditions related to abnormal lipid synthesis and metabolism, including cardiovascular disease, such as atherosclerosis; obesity; Type 2 diabetes; insulin resistance; hyperglycemia; Metabolic Syndrome; neurological disease; cancer; and liver steatosis. Formula (I).