CAS: 50840-23-8; 5-Methylpyrimidin-2-Amine

相似化合物

39268-71-8 1753-48-6 859957-10-1

上下游产品

CAS号22536-61-4 2-氯-5-甲基嘧啶 | CAS号209959-33-1 2-[双(叔丁氧羰基)氨基]-5-溴嘧啶 | CAS号544-97-8 二甲基锌 | CAS号50-01-1 盐酸胍 | CAS号42588-57-8 2-甲基-3-乙氧基丙烯醛 | CAS号3073-77-6 2-氨基-5-硝基嘧啶 | CAS号6407-34-7 N-methyl-2-Prop... | CAS号1780-31-0 2,4-二氯-5-甲基嘧啶 | CAS号7153-13-1 2-氨基-4,6-二氯-5-甲基嘧啶 | CAS号1780-36-5 2,4,6-三氯-5-甲基嘧啶 | CAS号599-88-2 磺胺培林

2-氨基-4,6-二氯-5-甲基嘧啶置于水,锌体系中,化学反应生成 2-氨基-5-甲基嘧啶
参考文献:Gerngross,Chemische Berichte,1905,Vol. 38,P. 3397
标题:Gerngross,Chemische Berichte,1905,Vol. 38,P. 3397

专利信息

专利号:WO-2024137329-A1
优先权日:2022-12-20
标 题:Methods for the synthesis of complement factor d inhibitors and intermediates thereof
发明人：HASHIMOTO AKIHIRO; TIPPARAJU SURESH KUMAR
权利人:ALEXION PHARMA INC
摘要:The present disclosure provides methods for the synthesis of complement factor D inhibitors and intermediates thereof.

专利号:US-7211668-B2
优先权日:2003-07-28
标 题 :PNA monomer and precursor
发明人：KIM SUNG KEE; LEE HYUNIL; LIM JONG CHAN; LEE SUNG HEE
权利人:PANAGENE INC
摘要:This application relates to monomers of the general formula (I) for the preparation of PNA (peptide nucleic acid) oligomers and provides method for the synthesis of both predefined sequence PNA oligomers and random sequence PNA oligomers: n nwhereinn E is sulfur or oxygen; J is nitrogen or C—R′; R1, R′ is independently H, halogen, alkyl, nitro, nitrile, alkoxy, halogenated alkyl, halogenated alkoxy or a functional group having one of following general formulae: n nwhereinn A 1 , A 2 , A 3 , A 4 , A 5 , is independently selected from H, halogen such as F, Cl, Br or I, CF 3 , alkyl, preferably C 1 –C 4 alkyl, nitro, nitrile, alkoxy, preferably C 1 –C 4 alkoxy, halogenated (such as F, Cl, Br and I) alkyl, preferably halogenated C 1 –C 4 alkyl, halogenated (such as F, Cl, Br and I) alkoxy, preferably halogenated C 1 –C 4 alkoxy, phenyl, and halogenated (such as F, Cl, Br and I phenyl; R2 is H or protected or unprotected side chain of natural or unnatural α-amino acid; and B is a natural or unnatural nucleobase, wherein when said nucleobase has an exocyclic amino function, said function is protected by protecting group which is labile to acids but stable to weak to medium bases in the presence of thiol.

专利号:US-7411065-B2
优先权日:2002-04-26
标 题 :PNA monomer and precursor
发明人：KIM SUNG KEE; LEE HYUNIL; LIM JONG CHAN; CHOI HOON; JEON JAE HOON; AHN SANG YOUL; LEE SUNG HEE; YOON WON JUN
权利人:PANAGENE INC
摘要:This application relates to monomers of the general formula (I) for the preparation of PNA (peptide nucleic acid) oglimers and provides method for the synthesis of both predefined sequence PNA oligomers and random sequence PNA oligomers: n nwhereinn E is nitrogen or C—R′; J is sulfur or oxygen; R′, R1, R2, R3, R4 is independently H, halogen, alkyl, nitro, nitrile, alkoxy, halogenated alkyl, halogenated alkoxy, phenyl or halogenated phenyl, R5 is H or protected or unprotected side chain of natural or unnatural α-amino acid; and B is a natural or unnatural nucleobase, wherein when said nucleobase has an exocyclic amino function, said function is protected by protecting group which is labile to acids but stable to weak to medium bases in the presence of thiol.

专利号:WO-2023114200-A2
优先权日:2021-12-14
标题 :Methods for the synthesis of complement factor d inhibitors and intermediates thereof

专利号:US-10308615-B2
优先权日:2015-05-29
标 题:Heterocyclic compounds as inhibitors of Vanin-1 enzyme
发明人：CASIMIRO-GARCIA AGUSTIN; CONDON JEFFREY SCOTT; FLICK ANDREW CHRISTOPHER; GOPALSAMY ARIAMALA; KIRINCICH STEVEN J; MATHIAS JOHN PAUL; STROBACH JOSEPH WALTER; XIANG JASON SHAOYUN; XING LI HUANG; WANG XIAOLUN
权利人:PFIZER
摘要:Compounds, pharmaceutically acceptable salts thereof, are disclosed wherein the compounds have the structure of n nas defined in the specification. Corresponding pharmaceutical compositions, methods of treatment, methods of synthesis, and intermediates are also disclosed.

专利号:US-8372971-B2
优先权日:2004-08-25
标 题:Heterocyclic compounds and methods of use
发明人：WRASIDLO WOLFGANG; DNEPROVSKAIA ELENA
权利人:TARGEGEN INC; WRASIDLO WOLFGANG; DNEPROVSKAIA ELENA
摘要:Heterocyclic compounds derived from benzotriazine, triazines, triazoles and oxadiazoles are disclosed. The methods of synthesis and of use of such heterocyclic compounds are also provided.