CAS: 521-24-4; Sodium 3,4-Dioxo-3,4-Dihydronaphthalene-1-Sulfonate

该化合物是一种属于环状烷基酮类别的化学化合物,其特点是一个装有两个芳香环和五角星功能组的引信环结构,该化合物一般是黄色至橙色固态,由于全氟辛烷磺酸组的存在,可溶于水中,这增加了其水的用途;在紫外线显示的频谱中表现出强烈吸收,使其作为染色剂和各种生物化学应用有用;1,2-纳菲松-4-硫酸盐经常被用作有机合成和分析化学的试剂,特别是在红氧反应中,并因其进行氧化和减少的能力而成为潜在指标;此外,该化合物在对酶动力学和生物污物的研究中也有应用;安全数据表明,与许多化学化合物一样,应谨慎处理,因为它在接触时可能构成健康风险.

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CAS号83-72-7 2-羟基-1,4萘醌 | CAS号86614-18-8 4-(propan-2-yla... | CAS号86614-20-2 2-(propan-2-yla... | CAS号86614-11-1 (Z)-4-hydroxy-3... | CAS号67-64-1 丙酮 | CAS号25107-73-7 4-(cyclohexylme... | CAS号26803-18-9 1,2-Naphthalene... | CAS号23673-39-4 4-(diethylamino... | CAS号10148-21-7 (3,4-dioxonapht... | CAS号17672-02-5 4-(methyl-pheny...

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    专利信息


    专利号:BR-112016022455-B1
    优先权日:2014-03-31
    标 题 :use of a supernatant from cultures of a strain of bacillus pumilus species, unnatural cosmetic or dermopharmaceutical composition; skin, stimulate collagen synthesis and / or hyaluronic acid synthesis, treatment of skin tightening and / or prevention of loss of skin firmness

    专利号:US-8673371-B2
    优先权日:2010-12-17
    标题:Composition for treating vitiligo or canities comprising extract from sophora japonica as active ingredient
    发明人：KIM YOUNG CHUL; KANG CHUL HO; PARK EUN YE; KIM SANG NAM
    权利人:KIM YOUNG CHUL; KANG CHUL HO; PARK EUN YE; KIM SANG NAM; KEIMYUNG UNIVERSITY INDUSTRY ACADEMIC COOPERATION FOUNDATION
    摘要:Disclosed is a composition for treating or preventing vitiligo or canities comprising Sophora japonica extract as an active ingredient. The Sophora japonica extract enhances melanin synthesis by increasing the activity of tyrosinase which is critical in intracellular melanin synthesis and promoting the expression of tyrosinase and TRP-2 mRNA. Furthermore, since the Sophora japonica extract is a natural substance with little cytotoxicity, it may be developed into a therapeutic agent for vitiligo and canities caused by depigmentation in skin and hair.

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    主要参考文献

    [参考文献]: Ayman A Gouda, Et Al. Spectophotometric Methods For Determination Of Cefdinir In Pharmaceutical Formulations Via Derivatization With 1,2-Naphthoquinone-4-Sulfonate And 4-Chloro-7-Nitrobenzo-2-Oxa-1, 3-Diazole. Drug Test Anal. 2012 Dec;4(12):991-1000.
    [参考文献]: Huai You Wang, Et Al. Spectrophotometric Determination Of Dapsone In Pharmaceutical Products Using Sodium 1,2-Naphthoquinone-4-Sulfonic As The Chromogenic Reagent. Spectrochim Acta A Mol Biomol Spectrosc. 2004 Oct;60(12):2933-9.
    [参考文献]: J A Kiernan, Et Al. A Histochemical Examination Of The Staining Of Kainate-Induced Neuronal Degeneration By Anionic Dyes. Biotech Histochem. 1998 Sep;73(5):244-54.
    [参考文献]: L G Martinez, Et Al. New Spectrophotometric Procedure For Determining Cefotaxime Based On Derivatization With 1,2-Naphthoquinone-4-Sulphonate Into Solid-Phase Extraction Cartridges--Application To Pharmaceutical And Urine Samples. J Chromatogr B Biomed Sci Appl. 1998 Oct 23;718(1):143-51.
    [参考文献]: Li Xiao Xu, Et Al. Spectrophotometric Determination Of Procaine Hydrochloride In Pharmaceutical Products Using 1,2-Naphthoquinone-4-Sulfonic Acid As The Chromogenic Reagent. Spectrochim Acta A Mol Biomol Spectrosc. 2003 Nov;59(13):3103-10.

    合成参考文献


    摘要:National Technical Information Service., AD691-490
    参考文献:10.1016/s0960-894x(02)00331-1
    摘要:Ahn JH, Cho SY, Ha JD, Chu SY, Jung SH, Jung YS, Baek JY, Choi IK, Shin EY, Kang SK, Kim SS, Cheon HG, Yang SD, Choi JK. Synthesis and PTP1B inhibition of 1,2-naphthoquinone derivatives as potent anti-diabetic agents. Bioorg Med Chem Lett. 2002 Aug 05;12(15):1941–6. doi: 10.1016/s0960-894x(02)00331-1.
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