CAS: 586-98-1; Pyridin-2-Ylmethanol

相似化合物

23579-92-2 1121-60-4 2524-52-9

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CAS号31181-90-5 5-溴吡啶-2-甲醛 | CAS号1121-60-4 吡啶-2-甲醛 | CAS号3731-51-9 2-(氨甲基)吡啶 | CAS号66310-15-4 2-pyridylmethyl... | CAS号6959-47-3 2-氯甲基吡啶盐酸盐 | CAS号274-59-9 [1,2,3]三唑并[1,5-a]吡啶 | CAS号2459-07-6 2-吡啶甲酸甲酯 | CAS号1007-49-4 2-吡啶乙酸甲酯 | CAS号144223-29-0 1-(2-吡啶基羰基)苯并三唑 | CAS号524955-09-7 [3-氯-4-(吡啶-2-甲氧... | CAS号55579-01-6 1-[(2-吡啶基)甲基]哌嗪 | CAS号35549-47-4 2-(2-氰乙基)吡啶 | CAS号492-73-9 2,2′-吡啶酮 | CAS号3731-51-9 2-(氨甲基)吡啶 | CAS号4377-33-7 2-氯甲基吡啶 | CAS号4329-81-1 2-苯胺甲基吡啶 | CAS号50501-38-7 6-(羟甲基)-2-吡啶甲腈 | CAS号18904-38-6 N-benzylpyridin...

2-吡啶甲酸乙酯置于potassium Tert-Butylate,氢气,C27H23Brmnn2O2P体系中,用 乙醇 作为反应溶剂,90.0 °C,5.0 Mpa 条件下,反应 20.0H,以45%的收率获得产物2-吡啶甲醇
参考文献:锰催化香紫苏内酯加氢制氨二醇
标题:锰催化香紫苏内酯加氢制氨二醇
摘要:钳形配合物:一种简单实用的方法,用于将 (+)-香紫苏内酯氢化为 (-)-Ambradiol.应用的锰催化剂可以从可商购的起始材料开始分两步制备.该程序可应用于许多其他酯类,突出了开发协议的多功能性.
DOI:10.1002/cctc.202101443

专利信息

专利号:US-8779121-B2
优先权日:2012-10-12
标题:Process for the synthesis of 3-(2-bromo-4,5-dimethoxyphenyl)propanenitrile, and application in the synthesis of ivabradine and addition salts thereof with a pharmaceutically acceptable acid
发明人：CARRANZA MARIA DEL PILAR; GARCIA ARANDA MARIA ISABEL; GONZALEZ JOSÉ LORENZO; SANCHEZ FRÉDÉRIC
权利人:SERVIER LAB
摘要:Process for the synthesis of the compound of formula (I): n nApplication in the synthesis of ivabradine, addition salts thereof with a pharmaceutically acceptable acid and hydrates thereof.

专利号:US-9090742-B2
优先权日:2013-06-28
标 题 :Facile synthesis of metalloporphyrin polymers
发明人：VAIL SEAN; EVANS DAVID
权利人:SHARP LAB OF AMERICA INC
摘要:A method is provided for synthesizing a metal (M) meso-tetraphenylporphyrin polymer. The method begins with the provision of a free-base (H 2 )-meso-tetra-4-(trialkylsilyl)ethynylphenylporphyrin (H 2 -tetra-C≡C-TriAS-TPP) including a trialkylsilyl (TriAS) moiety attached to an ethynyl termini. In response to a reaction with a metal (M)-containing material, the H 2 -tetra-C≡C-TriAS-TPP is converted to a metal (M)-tetra-4-(trialkylsilyl)ethynylphenylporphyrin (M-tetra-C≡C-TriAS-TPP). Then, the M-tetra-C≡C-TriAS-TPP is converted to a M-tetra-4-ethynylphenylporphyrin (M-tetra-C≡C-TPP) monomer by removing the trialkylsilyl (TriAS) moiety from the ethynyl termini. Finally, a plurality of M-tetra-C≡C-TPP monomers are coupled together to supply a metal (M)-meso-tetraphenylporphyrin polymer (M-poly-meso-TPP), whereby meso-phenyl groups of adjacent M-tetra-C≡C-TPP monomers in the M-poly-meso-TPP are connected through a butadiyne linking moiety. In one aspect, the metal is zinc.

专利号:US-6448058-B1
优先权日:1997-09-12
标 题:Methods for solid phase synthesis of mercapto compounds and derivatives, combinatorial libraries thereof and compositions obtained thereby
发明人：PATEL DINESH V; NGU KHEHYONG; ZHOU JIANPING
权利人:VERSICOR INC
摘要:Methods of preparing combinatorial libraries of mercapto (thiol) compounds them and compositions obtained therefrom are disclosed. The compounds are synthesized on a solid support. Following synthesis, the compounds are optionally cleaved from the support. One such method of synthesis involves attack of an S-protected nucleophile on a resin functionalized with a leaving group. The invention also provides for screening the mercapto compounds for bioactive compounds; in particular, for inhibitors of MMPs.

专利号:US-5756790-A
优先权日:1995-09-29
标题 :Optically active cobalt (II) complexes and method for the preparation of optically active alcohols
发明人：MUKAIYAMA TERUAKI; YOROZU KIYOTAKA; NAGATA TAKUSHI; YAMADA TORU; SUGI KIYOAKI
权利人:MITSUI PETROCHEMICAL IND
摘要:The invention provides a method for preparing an optically active alcohol comprising the step of reacting a ketone compound with a hydride reagent in the presence of an optically active metal compound. The resulting optically active alcohols are useful as intermediates for the synthesis of physiologically active compounds such as drugs and pesticides, functional materials such as liquid crystals, and raw materials for synthesis in fine chemistry. A novel optically active cobalt (II) complex useful as a catalyst is also provided.

专利号:WO-0026190-A1
优先权日:1998-10-30
标 题:Chiral amino alcohol derivatives of pyridine, a method for the manufacture thereof and their use as catalysts
发明人：NEVALAINEN VESA; SYLVESTRE DEGNI
权利人:NESTE CHEMICALS OY; NEVALAINEN VESA; SYLVESTRE DEGNI
摘要:The invention relates to chiral amino alcohol derivatives of pyridine, which compounds are useful as catalysts in combination with organic zinc compounds for asymmetric induction reactions and more particularly for enantioselective synthesis of optically active alcohols from aldehydes. The invention also relates to a process for the preparation of the said amino alcohol derivatives of pyridine and to a method for the manufacture of optically active alcohols from aldehydes in the presence of organic zinc compounds and amino alcohol derivatives of pyridine.

专利号:US-10017474-B1
优先权日:2018-01-02
标题 :Method of synthesizing (E)-1,2-di(pyridin-2-yl) ethene-1,2-diol
发明人：AL-ZEQRI NABIL AHMED QASSIM; WARAD ISMAIL KHALIL; AWWADI FIRAS FANDI; ALSALME ALI MOHAMMED; ALALI ANAS KHALED ABED; ZARROUK ABDELKADER
权利人:UNIV KING SAUD
摘要:The method of synthesizing (E)-1,2-di(pyridine-2-yl)ethene-1,2-diol involves dimerization of 2-pyridinecarboxaldehyde (also referred to herein as “picolinaldehydeâ€?). The synthesis of the desired ethene-1,2-diol is achieved using a Cu(II) catalyst to dimerize picolinaldehyde under mild conditions. Preferably, the Cu(II) catalyst is a Cu(II)/neocuproine (2,9-dimethyl-1,10-phenanthroline) complex, or other Cu(II)/phen complex. The reaction in this embodiment may occur at room atmosphere and in ambient light conditions using a water/ROH solvent. The exemplary ethene-1,2-diol product, (E)-1,2-di(pyridin-2-yl)ethene-1,2-diol has the following structural formula: