CAS: 18829-70-4; (2S,3R)-2-(3,4-Dihydroxyphenyl)Chroman-3,5,7-Triol

该化合物是一种芳香有机化合物,其特征是附于苯环的两种氢氧基(-OH)组;一种无色的黄色液体,其香味和芳香味,可溶于水,酒精和醚;该化合物在室内温度周围显示出一个熔点,沸点因大气压力而异;(-)-Catechol因其抗氧化特性而闻名,并用于各种用途,包括作为制药,农用化学品和染料合成的前体;还在生产某些聚合物和树脂方面发挥作用;该化合物可发生氧化,形成五角形,对光和空气敏感,可能导致其降解;在安全方面,(-)-Catechol可能对皮肤和眼睛产生刺激,在实验室或工业环境中处理时应采取适当的预防措施.

结构式图片

欧盟法规

ECHA物质C&L通报REACH预注册

上下游产品

(2R,3R)-2-(3,4-dihydroxyphenyl)-3,4-dihydro-1[2H]-benzopyran-3,5,7-triol 4pr°Cyanidin B4 aesculitannin D (-)-catechin gallate ent-catechin 3',4',5,7-tetra-O-methyl ether catechin catechin 8)-ent-epicatechincatechin-(4α-8)-ent-epicatechin

合成工艺路线路线简述

    2,3',4,4',6-Penta-O-Methoxymethyl-Retro-Chalcone置于palladium On Activated Charcoal 盐酸,氯化亚砜,甲基磺酰胺,Ad-Mix-β,氢气,1,8-二氮杂双环[5.4.0]十一碳-7-烯体系中,用 甲醇,乙醇,二氯甲烷,水,叔丁醇,苯 用作溶剂,化学反应 29.08H,反应生成(-)-儿茶素
    参考文献:Nel,Reinier J. J.; Heerden,Pieter S. Van; Rensburg,Hendrik Van,Journal Of Chemical Research,Miniprint,1999,# 10,P. 2610-2625
    标题:Nel,Reinier J. J.; Heerden,Pieter S. Van; Rensburg,Hendrik Van,Journal Of Chemical Research,Miniprint,1999,# 10,P. 2610-2625

    海关参考信息

    专利信息


    专利号:US-2004266699-A1
    优先权日:2001-10-04
    标 题 :Flavonoid compounds capable of modifying the dynamic and/or physical state of biological membranes and to stimulate the endogenous synthesis of stress proteins in eukaryotic cells, relative synthesis and their use
    发明人:PORTA AMALIA
    摘要:The invention relates to flavonoids compounds of formula (I) and (II) capable of modifying the dynamic and/or physical state of biological membranes and to stimulate the endogenous synthesis of stress proteins in eukaryotic cells. Such compounds are molecules of plant origin or synthetic. The invention also describes a method to identify, purify and chemically synthesize such flavonoid compounds and test their efficacy through their capacity to stimulate the transcription of stress genes and as a consequence, to interact with biological membranes with alteration of their relative physical state. Such compounds and corresponding pharmaceutically acceptable derivatives and/or salts have applications in the areas of pharmaceuticals, more specifically in cosmetics and dermatology, for all those afections related to an alteration of the expression of stress genes.

    专利号:US-9428482-B2
    优先权日:2011-01-27
    标 题 :Process for synthesis of polyphenols
    发明人:DUGAR SUNDEEP; MAHAJAN DINESH; PANTELIS PETER GIANNOUSIS; SINGH VIJAY; KAPOOR KAMAL KISHORE
    权利人:DUGAR SUNDEEP; MAHAJAN DINESH; PANTELIS PETER GIANNOUSIS; SINGH VIJAY; KAPOOR KAMAL KISHORE; SPHAERA PHARMA PTE LTD
    摘要:The present invention provides synthetic processes for preparing racemic and/or optically pure epicatechin, epigallocatechin and related polyphenols as such or as their variously functionalized derivatives. A principle objective of the disclosure is to provide a new and useful method of synthesis to obtain polyphenols in isomerically pure and/or racemic forms.

    专利号:US-8143308-B2
    优先权日:2005-04-28
    标题 :Synthesis of oligo/poly(catechins) and methods of use
    发明人:BRUNO FERDINANDO F; KUMAR JAYANT; NAGARAJAN SUBHALAKSHMI; BRAUNHUT SUSAN J; NAGARAJAN RAMASWAMY; SAMUELSON LYNNE A; MCINTOSH DONNA; FOLEY KLAUDIA
    权利人:BRUNO FERDINANDO F; KUMAR JAYANT; NAGARAJAN SUBHALAKSHMI; BRAUNHUT SUSAN J; NAGARAJAN RAMASWAMY; SAMUELSON LYNNE A; MCINTOSH DONNA; FOLEY KLAUDIA; UNIV MASSACHUSETTS LOWELL; US ARMY
    摘要:A method for synthesizing a biocompatible, water-soluble oligo/polyflavanoid, includes polymerizing an optionally substituted flavanoid with a polymerization agent in the presence of a biocompatible polymerization solubilizer, thereby producing the biocompatible, soluble oligo/polyflavanoid. Also included is a biocompatible, soluble, oligo/polyflavanoid or a pharmaceutically acceptable salt, solvate, or complex thereof. Also included are methods of treating a subject for cancer, cardiac damage, viral infection, and obesity.

    专利号:EP-1921076-A1
    优先权日:2002-10-11
    标题:systhesis of procyanidin B2
    发明人:CASTILLO GERARDO M; NGUYEN BETH P; CHOI PAULA Y; LARSEN LESLEY; LORIMER STEPHEN D; SNOW ALAN D
    权利人:PROTEOTECH INC
    摘要:Methods for the synthesis of procyanidin B2 are disclosed. The synthetic methods utilize epicatechin as a starting material and produce procyanidin BZ in high yields.

    专利号:WO-2024220193-A1
    优先权日:2023-04-21
    标题 :Methods for preparing (-)-epicatechin
    发明人:PAIS GODWIN
    权利人:MARS INC
    摘要:Methods steps for the synthesis of (-)-epicatechin are provided herein. The synthetic methods are provided in two phases: (1) synthesis of epoxide intermediates and (2) synthesis of (-)-epicatechin.

    专利号:JP-2020117531-A
    优先权日:2013-01-26
    标题 :Novel process for synthesis of catechins
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