CAS: 2497-02-1; N-Acetylhistidine

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39145-52-3 3253-17-6 213178-97-3

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CAS号108-24-7 乙酸酐 | CAS号645-35-2 L-组氨酸盐酸盐 | CAS号71-00-1 L-组氨酸 | CAS号75-36-5 乙酰氯 | CAS号23506-34-5 2-[[(2S)-2-acet... | CAS号61389-34-2 (2S)-2-[[(2S)-2... | CAS号61389-32-0 (2S)-2-[[(2S)-2... | CAS号463-51-4 乙烯酮 | CAS号934-87-2 S-苯基硫代乙酸酯 | CAS号17336-14-0 2-乙酰氧基-5-硝基苯甲酸 | CAS号36097-48-0 N-乙酰-L-组氨酸甲酯 | CAS号71-00-1 L-组氨酸 | CAS号6367-11-9 (S)-2-乙酰氨基-3-(1...

N-Acetylated L-Histidylglycine置于c14H36N6O2Pt2(4+),水体系中,化学反应 72.0H,反应生成N-乙酰-L-组氨酸
参考文献:各种吡嗪桥联的铂(II)配合物的合成,光谱和x射线表征:1 H NMR比较研究其催化甲硫氨酸和组氨酸二肽水解的能力
标题:各种吡嗪桥联的铂(II)配合物的合成,光谱和x射线表征:1 H NMR比较研究其催化甲硫氨酸和组氨酸二肽水解的能力
摘要:摘要四种吡嗪(pz)桥连的pt(II)配合物[{pt(1,3-Pd)cl} 2(μ-Pz)] Cl 2.licl(1)(1,3-Pd = 1,3-丙二胺),[{pt(2,2-Dime-1,3-Pd)cl} 2(μ-Pz)] Cl 2.2 [li(h 2 O)4] Cl.2H 2 O(2) (2,2-Dime-1,3-Pd = 2,2-二甲基-1,3-丙二胺),[{pt(1,3-Pnd)cl} 2(μ-Pz)](clo 4)2 .h 2 O(3)(1,3-Pnd =(+/-)-1,3-戊二胺)和[{pt(1,3-Pnd)cl} 2(μ-Pz)] Cl 2.2 [pt合成了(1,3-Pnd)cl 2].2H 2 O(4).已经对化合物1-3进行了NMR和uv-Vis光谱表征,对配合物2和4进行了单晶x射线分析.4晶体中的原子分布表明存在一种无序现象,这可能归因于[{pt(1,3-Pnd)cl} 2(μ-Pz)]
Doi:10.1016/j.Poly.2016.06.011

专利信息

专利号:US-2012149868-A1
优先权日:2008-05-15
标题:Purification of peptides prepared by solid phase synthesis
发明人：KORNBECK CAMILLA; HANSEN THOMAS BUDDE
权利人:KORNBECK CAMILLA; HANSEN THOMAS BUDDE; NOVO NORDISK AS
摘要:The invention relates to an effective process for purifying a peptide which has been prepared by solid phase peptide synthesis. Also encompassed by the invention is a kit comprising reagents for said process and the purified peptide obtained by said process.

专利号:US-9732137-B2
优先权日:2007-12-28
标 题 :Semi-recombinant preparation of GLP-1 analogues
发明人：LAU JESPER FAERGEMAN; ANDERSEN ASSER SLOTH; BLOCH PAW; LAU JESPER; GARIBAY PATRICK WILLIAM; KRUSE THOMAS; NØRBY INGA SIG NIELSEN; JESSEN CLAUS ULRICH; CHRISTENSEN CASPAR; NORRILD JENS CHRISTIAN
权利人:LAU JESPER FAERGEMAN; ANDERSEN ASSER SLOTH; BLOCH PAW; LAU JESPER; GARIBAY PATRICK WILLIAM; KRUSE THOMAS; NØRBY INGA SIG NIELSEN; JESSEN CLAUS ULRICH; CHRISTENSEN CASPAR; NORRILD JENS CHRISTIAN; NOVO NORDISK AS
摘要:A semi-recombinant method for the production of GLP-1 analogues and derivatives with non-proteogenic amino acids in the N-terminal part combining the use of recombinant expression techniques and chemical peptide synthesis.

专利号:US-9567368-B2
优先权日:2013-11-29
标 题:Peptide tyrosinase activators
发明人：HANTASH BASIL M; UBEID ANAN ABU
权利人:ESCAPE THERAPEUTICS INC
摘要:Peptides that increase melanin synthesis are provided. These peptides include pentapeptides YSSWY (SEQ ID NO: 1), YRSRK (SEQ ID NO: 2), and their variants. The peptides may activate the enzymatic activity of tyrosinase to increase melanin synthesis. The pharmaceutical, cosmetic, and other compositions including the peptides are also provided. The methods of increasing melanin production in epidermis of a subject are provided where the methods include administering compositions comprising an amount of one or more peptides effective to increase the melanin production. The methods also include treating vitiligo or other hypopigmentation disorders with compositions including one or more peptides.

专利号:US-2023089723-A1
优先权日:2020-03-06
标 题:Amino acid compositions and methods for muscle and myotube modulation
发明人：COMB WILLIAM; COKOL MURAT; KULKARNI TRIPTI
权利人:AXCELLA HEALTH INC
摘要:This disclosure provides compositions comprising amino acid entities. The disclosure also provides methods for increasing myogenesis, increasing muscle protein synthesis, increasing muscle mass, improving muscle quality or enhancing muscle function comprising administering an effective amount of the compositions to a subject in need thereof.

专利号:US-2010160556-A1
优先权日:2007-03-21
标题:GLP-1 Fusion Peptides Conjugated to Polymer(s), Their Production and Use
发明人：WALLRAPP CHRISTINE; THOENES ERIC; GEIGLE PETER
权利人:WALLRAPP CHRISTINE; THOENES ERIC; GEIGLE PETER
摘要:The present invention provides fusion peptides having GLP-1 activity and enhanced stability in vivo, in particular resistancy to dipeptidyl peptidase IV conjugated to polymers, thereby forming conjugate molecules. The fusion peptide of the conjugate molecule comprises as component (I) N-terminally a GLP-1(7-35, 7-36 or 7-37) sequence and as component (II) C-terminally a peptide sequence of at least 9 amino acids or a functional fragment, variant or derivative thereof. A synthetic polymer and/or a protein, e.g transferrin or albumin, is covalently or non-covalently bound to the fusion peptide to form the conjugate molecule. Component (II) is preferably a full or partial version of IP2 (intervening peptide 2). A preferred embodiment comprises the sequence GLP-1(7-35, 36 or 37)/IP2/GLP-1(7-35, 36 or 37) or GLP-2 and a polymeric component, e.g. a natural or non-natural polymer. The fusion peptide may be produced in engineered cells or synthetically and is e.g. conjugated to the polymeric component by chemical synthesis. The conjugate molecule may be used for the preparation of a medicament for treating various diseases or disorders, e.g. diabetes type 1 or 2, apoptosis related diseases or neurodegenerative disorders.

专利号:CN-101735305-B
优先权日:2010-01-25
标 题:Synthesis method of L-carnosine