CAS: 4072-67-7; 1,1'-([1,1'-Biphenyl]-4,4'-Diyl)Bis(2-Bromoethanone)

上下游产品

CAS号787-69-9 4,4'-二乙酰联苯 | CAS号92-52-4 联苯 | CAS号598-21-0 溴乙酰溴 | CAS号15172-86-8 Pyridinium,1,1'... | CAS号20275-19-8 1,1′-(p′p′-BIPH... | CAS号19035-84-8 4-Picolinium, 1... | CAS号312-45-8 半胆碱-3 | CAS号792-74-5 联苯二甲酸二甲酯 | CAS号13717-24-3 alpha,alpha-bis... | CAS号123489-65-6 4,4'-Bis(pyrrol... | CAS号123489-68-9 4,4'-Bis((2-met... | CAS号123489-64-5 4,4'-Bis(pyrrol... | CAS号123489-69-0 N,N'-((1,1'-Bip...

4-溴苯乙酮置于2,2'-联吡啶,氯化镍二甲氧基乙烷,溴,四丁基碘化铵,Lithium Chloride体系中,用 二氯甲烷,N,N-二甲基乙酰胺 作为反应溶剂,化学反应 4.58H,反应生成 4,4'-二(2-溴乙酰基)联苯
参考文献:Micro-Electrolysis Reactor For Ultra Fast,Oxidant Free,C-C Coupling Reaction And Synthesis Of Daclatasvir Analogs Thereof
标题:Micro-Electrolysis Reactor For Ultra Fast,Oxidant Free,C-C Coupling Reaction And Synthesis Of Daclatasvir Analogs Thereof
摘要:本发明涉及一种连续微电流反应器系统,用于制备对称联苯及其类似物的超快速,无氧化剂的c-c偶联反应.本发明还涉及一种用于制备抗病毒药物达卡他韦(通用式i)的方法.

专利信息

专利号:US-11344858-B2
优先权日:2019-05-02
标 题 :Micro-electrolysis reactor for ultra fast, oxidant free, C—C coupling reaction and synthesis of daclatasvir analogs thereof
发明人：SINGH AJAY KUMAR; PABBARAJA SRIHARI; GHOSH SUBHASH; BHUSHAN MAHAJAN; MUJAWAR TAUFIQUEAHMED
权利人:COUNCIL SCIENT IND RES
摘要:The present invention relates to a continuous micro-electro-flow reactor system for ultra-fast, oxidant free, C—C coupling reaction for making symmetrical biaryls and analogs thereof. This invention further relates to the said process for preparation of antiviral drug, daclatasvir of general formula I.

专利号:US-2020346182-A1
优先权日:2019-05-02
标 题 :Micro-electrolysis reactor for ultra fast, oxidant free, c-c coupling reaction and synthesis of daclatasvir analogs thereof