61-19-8 = 56-65-5 + 2596-55-6 反应条件:1.1R:R:Na4P2O7,R:Naoh,C:Mgcl2,S:H2O,0°C,Ph 7.51.2R:Etn=c=n(Ch2)3Nme2 HCL,10 S,0°C; 0°C 标题:Spontaneous Formation Of Rna Strands,Peptidyl Rna,And Cofactors 作者:By Jauker,Mario Et Al 参考文献:Angewandte Chemie 日期:2015 卷标:54(48) 页码:14564-14569]
288-32-4 + 4578-31-8 = 56-65-5 + 58-64-0 反应条件:1.1R:S:H2O,S:Mecn,1 H,40°C2.1R:Na Orthophosphate 标题:One-Pot Synthesis Of Nucleotides In Water Medium 作者:By Depaix,Anais Et Al 参考文献:Phosphorus 日期:2019 卷标:194(4-6) 页码:335-336]
61-19-8 = 56-65-5 + 1062-98-2 + 14535-90-1 + 56983-23-4 + 58-64-0 反应条件:1.1R:4-Ethylmorpholine,R:Mgcl2,S:Thf,S:H2O 标题:Magnesium(Ii) Ion-Mediated Conversion Of Mono- And Oligonucleotides To 5'-Polyphosphates In Aqueous Solution 作者:By Sawai,Hiroaki Et Al 参考文献:Tetrahedron Letters 日期:1993 卷标:34(30) 页码:4801-4]
73-24-5 + 50-69-1 = 56-65-5 + 61-19-8 + 58-64-0 反应条件:1.1R:Po43-,R:H2O,2 H,150°C 标题:Confinement And Time Immemorial: Prebiotic Synthesis Of Nucleotides On A Porous Mineral Nanoreactor 作者:By Rodrigues,Francisco Et Al 参考文献:Journal Of Physical Chemistry Letters 日期:2019 卷标:10(15) 页码:4192-4196]
99-50-3 + 63-68-3 + 58-61-7 = 56-65-5 + 645-08-9 + 121-34-6 + 58-64-0 反应条件:1.1R:Mgcl2,R:Kcl,C:9026-44-2,C:9013-02-9,C:61-19-8,C:9012-25-3,C:9012-52-6,C:29908-03-0,S:H2O,20 H,37°C,Ph 7.51.2R:HCLo4 标题:Catalytic Alkylation Using A Cyclic S-Adenosylmethionine Regeneration System 作者:By Mordhorst,Silja Et Al 参考文献:Angewandte Chemie 日期:2017 卷标:56(14) 页码:4037-4041
专利号:US-7294486-B2 优先权日:2001-09-05 标 题:Enzymatic process for the synthesis of organo-fluorine compounds 发明人:O'HAGAN DAVID; SCHAFFRATH CHRISTOPH 权利人:UNIV ST ANDREWS 摘要:There is described a process for the synthesis of a fluoronucleoside compound, said process comprising mixing a substrate and an enzyme from Streptomyces cattelya as catalyst. The process may be used to produce an 18 F labelled fluoronucleoside compound. There is also described an enzyme derived from Streptomyces cattelya which has the capacity to catalyse the synthesis of a fluoronucleoside compound.
专利号:US-2005153390-A1 优先权日:2002-05-14 标 题 :Lyophilized preparation for synthesis of cell-free protein 发明人:ENDO YAETA; OGASAWARA TOMIO 权利人:CELLFREE SCIENCES CO LTD 摘要:Lyophilized preparations from cell extract for use in cell-free protein, which exhibit an activity for protein synthesis being in no way inferior to that exhibited in low-temperature storage; and a method of utilizing the same. In particular, preparations are formed by performing lyophilization after reducing the concentration of deliquescent substances in a solution containing cell extract for synthesis of cell-free protein to a level not detrimental to the quality of preparations after lyophilization.
专利号:US-2025290108-A9 优先权日:2022-09-13 标 题 :One-Step Method for Synthesis of Circular RNA 发明人:QI SHAOJUN; YAN HUAYUAN; GAO PENG 权利人:SUZHOU ABOGEN BIOSCIENCES CO LTD 摘要:Provided are methods of preparing a circular RNA, comprising providing a template DNA, wherein the template DNA comprises a sequence encoding a precursor RNA, in a reaction solution to allow synthesis of precursor RNA by in vitro transcription of the template DNA and allowing the precursor RNA to self-splice, thereby producing a circular RNA, wherein the in vitro transcription of the template DNA and the self-splicing (i.e., circularization) of the precursor RNA are carried out in the same reaction solution under the same reaction conditions (e.g., the same reaction temperature). The method can be carried out in a single reaction vessel and does not require a step of purifying the precursor RNA before allowing the precursor RNA to self-splice.
专利号:US-5866378-A 优先权日:1995-10-06 标 题:Process for the synthesis of nucleotide-6-deoxy-D-xylo-4-hexuloses 发明人:MARQUARDT RUEDIGER; HOERSCH BRIGITTE; SEIFFERT-STOERIKO ANDREAS; STEIN ANDREAS; ZERVOSEN ASTRID; ELLING LOTHAR; KULA MARIA REGINA; VERSECK STEFAN; DISTLER JUERGEN; PIEPERSBERG WOLFGANG 权利人:HOECHST AG 摘要:The present invention relates to processes for the enzymatic synthesis of nucleotide-6-deoxy-D-xylo-4-hexuloses starting from a nucleoside monophosphate (NMP). These processes comprise simultaneous incubation of the following substances in a buffer solution: n (a) substrates comprising a nucleoside monophosphate, phosphoenolpyruvate, adenosine triphosphate, and sucrose; and n (b) enzymes comprising pyruvate kinase, nucleoside-monophosphate kinase, sucrose synthase and deoxythymidine-D-glucose 4,6dehydratase.
专利号:US-8580949-B2 优先权日:2009-07-27 标题:Enzymatic synthesis of carba-NAD 发明人:DUEFEL HARTMUT; HEINDL DIETER; HORN CARINA; MEIER THOMAS; SCHMUCK RAINER 权利人:DUEFEL HARTMUT; HEINDL DIETER; HORN CARINA; MEIER THOMAS; SCHMUCK RAINER; ROCHE DIAGNOSTICS OPERATIONS 摘要:The disclosure concerns the enzymatic synthesis of stable analogues of nicotinamide adenine dinucleotide NAD/NADH and nicotinamide adenine dinucleotide phosphate NADP/NADPH, the so-called “carba-NADsâ€?, i.e. analogues of NAD/NADH or NADP/NADPH, respectively, comprising a carbacyclic sugar instead of ribose.
专利号:US-11517764-B2 优先权日:2018-11-30 标题:Light irradiation device for synthesis of functional substance in a human body 发明人:BAE HEE HO; YOON YEONG MIN; LEE A YOUNG 权利人:SEOUL VIOSYS CO LTD 摘要:A light irradiation device includes a first light source emitting first light in a visible wavelength band and a second light source emitting second light, in which at least part of a wavelength band is different from a wavelength band of the first light source and which catalyzes synthesis of a functional substance in a target to which light is applied. The second light includes light in a wavelength band of ultraviolet B.
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合成参考文献
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