CAS: 9008-22-4; Laminarin

专利信息

专利号:EP-2354120-A1
优先权日:2003-08-20
标题 :Synthesis of acyloxyalkyl carbamate prodrugs and intermediates thereof
发明人：GALLOP MARK A; YAO FENMEI; LUDWIKOW MARIA J; PHAN THU; PENG GE
权利人:XENOPORT INC
摘要:The present invention relates to acyloxyalkyl carbamate prodrugs of (±)-4-amino-3-(4-fluorophenyl)butanoic acid and analogs thereof, pharmaceutical compositions thereof, methods of making prodrugs of (±)-4-amino-3-(4-fluorophenyl)butanoic acid and analogs thereof, methods of using prodrugs of (±)-4-amino-3-(4-tluorophenyl)butanoic acid and analogs thereof, and pharmaceutical compositions thereof for treating or preventing common diseases and/or disorders such as spasticity and/or acid reflux disease. The present invention also relates to acyloxyalkyl carbamate prodrugs of (±)-4-amino-3-(4-fluorophenyl)butanoic acid and analogs thereof which are suitable for oral administration and to sustained release oral dosage forms thereof.

专利号:US-11180740-B2
优先权日:2018-04-23
标 题 :Synthesis of glucan comprising beta-1,3 glycosidic linkages with beta-1,3-glucan phosphorylase enzymes
发明人：YU ZHEYONG; KRALJ SLAVKO; BEHABTU NATNAEL; ZHANG ZHENGHONG; HOWE LAURIE A
权利人:DANISCO US INC
摘要:Reaction compositions are disclosed herein comprising at least water, alpha-glucose-1-phosphate (alpha-G1P), an acceptor molecule, and a beta-1,3-glucan phosphorylase enzyme. These reactions can synthesize oligosaccharides and polysaccharides with beta-1,3 glycosidic linkages. Further disclosed are methods of isolating beta-1,3-glucan.

专利号:JP-2005296810-A
优先权日:2004-04-12
标题 :Method for preparing catalyst for synthesis of unsaturated carboxylic acid, catalyst for synthesis of unsaturated carboxylic acid, and method for synthesis of unsaturated carboxylic acid

专利号:WO-9848807-A1
优先权日:1997-04-25
标题:Hyaluronate synthesis inhibitors
发明人：UEKI NOBORU; HIGASHINO KAZUYA; TAGUCHI TOMOHIRO; TAKAHASHI MASAYUKI; ADACHI MASAKAZU
权利人:OTSUKA PHARMA CO LTD; UEKI NOBORU; HIGASHINO KAZUYA; TAGUCHI TOMOHIRO; TAKAHASHI MASAYUKI; ADACHI MASAKAZU
摘要:Hyaluronate synthesis inhibitors containing an efficacious amount of at least one compound selected from carbostyryl derivatives represented by general formula (I) and salts thereof and pharmaceutically acceptable carriers. In Formula (I), R represents benzoyl optionally having on the phenyl ring 1 to 3 linear or branched C1-6 alkoxy groups; and the carbon-carbon bond between the 3- and 4-positions of the carbostyryl skeleton is a single or double bond. These preparations are useful in treating various fibroid diseases and pathosis caused by the excessive production of hyaluronic acid.

专利号:WO-9808865-A1
优先权日:1996-08-30
标 题:CAP-BINDING DOMAIN OF HUMAN EUKARYOTIC PROTEIN SYNTHESIS INITIATION FACTOR eIF-4E AND THE USE THEREOF
发明人：GOSS DIXIE J; FRIEDLAND DIANA
权利人:LIFE TECHNOLOGIES INC; GOSS DIXIE J; FRIEDLAND DIANA
摘要:Binding of eIF-4E to the 5'm7G cap structure of eukaryotic mRNA signals the initiation of protein synthesis. In the present invention, the binding site cap-binding domain of eIF-4E was identified as the region containing the sequence Trp?113 to Arg122¿. Thus, in a first preferred embodiment the present invention provides a truncated peptide of the cap binding protein consisting essentially of the mRNA cap-binding domain. Specifically, the invention concerns eIF-4E cap binding peptide and its variants. In additional preferred embodiments, the invention provides an isolated nucleic acid molecule which encodes a truncated peptide of the eIF-4E protein consisting essentially of the mRNA cap-binding domain of eIF-4E; a recombinant vector and host cell comprising the above-described nucleic acid molecule; and a recombinant peptide produced thereby. The invention further provides the truncated or recombinant peptides immobilized on a solid support, a resin comprising the truncated or recombinant peptides immobilized on a solid support, methods and kits for isolating a capped mRNA molecule, and methods and kits for producing a full-length cDNA molecule.

专利号:WO-2017033119-A1
优先权日:2015-08-25
标题 :Compositions and methods for the treatment of liver metabolic diseases
发明人：RAO M SURYA
权利人:RAO M SURYA
摘要:The invention relates to the compositions of formula I and formula II or its pharmaceutical acceptable polymorphs, solvates, enantiomers, stereoisomers and hydrates thereof. The pharmaceutical compositions comprises a salt of bile acid and the methods for treating or preventing liver diseases, fatty liver, NASH, bile acid synthesis disorders due to single enzyme defects, gallstones, peroxisomal disorders may be formulated for oral, buccal, rectal, topical, transdermal, transmucosal, intravenous, parenteral administration, syrup, or injection. Such compositions may be used to treatment of NASH, fatty liver, liver cirrhosis and Bile acid synthesis disorders due to single enzyme defects, gallstones and peroxisomal disorders.