CAS: 1007-48-3; Pyridin-4-Ylmethyl Acetate

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586-95-8 65737-59-9 1570-45-2

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CAS号586-95-8 4-吡啶甲醇 | CAS号75-36-5 乙酰氯 | CAS号108-24-7 乙酸酐 | CAS号6844-47-9 4-三甲基甲硅烷基甲基吡啶 | CAS号3240-34-4 碘苯二乙酸 | CAS号1003-67-4 4-甲基吡啶-N-氧化物 | CAS号2466-76-4 1-乙酰基咪唑 | CAS号108-89-4 4-甲基吡啶 | CAS号127-09-3 乙酸钠 | CAS号586-95-8 4-吡啶甲醇 | CAS号14061-11-1 (1-methylpyridi...

4-甲基吡啶置于正丁基锂,四丁基氟化铵体系中,用 四氢呋喃,正己烷,二氯甲烷 用作溶剂,化学反应 21.0H,反应生成吡啶-4-甲基乙酸酯
参考文献:Oxidation Of Substituted Pyridines Pyrchrsime3 (R=h,Me,Ph) And Substituted Quinolines Qnch2Sime3 With Hypervalent Iodine Reagents
标题:Oxidation Of Substituted Pyridines Pyrchrsime3 (R=h,Me,Ph) And Substituted Quinolines Qnch2Sime3 With Hypervalent Iodine Reagents
摘要:
Doi:10.3987/com-96-7397

专利信息

专利号:US-4500535-A
优先权日:1979-10-15
标 题:Method of regulating the immune response with pyridine derivatives
发明人：LOMBARDINO JOSEPH G; HARBERT CHARLES A
权利人:PFIZER
摘要:A series of 4-(2-carboxymethylthiomethyl)pyridines and related compounds, and their pharmaceutically acceptable salts, are disclosed as having immunoregulatory activity. Preferred compounds include 4-(2-carboxymethylthiomethyl)pyridine [alternatively named 2-(4-picolylthio)acetic acid] and (C 1 -C 4 )alkyl esters thereof, and 4-(1-formylmethylthiomethyl)-pyridine [alternatively named 2-(4-picolylthio)acetaldehyde] and bis(C 1 -C 4 )alkyl or cyclic acetals thereof. These acids, esters, aldehydes and acetals also have utility as intermediates in the synthesis of the corresponding 4-(2-hydroxyethylthiomethyl)pyridines.

专利号:US-4371696-A
优先权日:1980-07-14
标 题 :Certain pyridine methylthio acetaldehyde derivatives and non-cyclic and cyclic acetals thereof
发明人：LOMBARDINO JOSEPH G; HARBERT CHARLES A
权利人:PFIZER
摘要:A series of 4-(2-carboxymethylthiomethyl)pyridines and related compounds, and their pharmaceutically acceptable salts, are disclosed as having antiinflammatory and immunoregulatory activity. Preferred compounds include 4-(2-carboxymethylthiomethyl)pyridine [alternatively named 2-(4-picolylthio)acetic acid] and (C 1 -C 4 )alkyl esters thereof, and 4-(1-formylmethylthiomethyl)pyridine [alternatively named 2-(4-picolylthio)-acetaldehyde] and bis(C 1 -C 4 )alkyl or cyclic acetals thereof. These acids, esters, aldehydes and acetals also have utility as intermediates in the synthesis of the corresponding 4-(2-hydroxyethylthiomethyl)pyridines.

专利号:US-2008176865-A1
优先权日:2005-06-15
标 题:Substituted arylpyrazoles
发明人：BILLEN DENIS; BOYLE JESSICA; CRITCHER DOUGLAS JAMES; GETHIN DAVID MORRIS; HALL KIM THOMAS; KYNE GRAHAM MICHAEL
权利人:PFIZER LTD
摘要:This invention relates to a range of 1-aryl-4-cyclopropylpyrazoles in which the cyclopropyl ring is substituted at the angular position, and pharmaceutically acceptable salts and solvates thereof, to compositions comprising such compounds, processes to their synthesis and their use as parasiticides.

专利号:US-7645786-B2
优先权日:2005-06-15
标题:Substituted arylpyrazoles
发明人：BILLEN DENIS; BOYLE JESSICA; CRITCHER DOUGLAS JAMES; GETHIN DAVID MORRIS; HALL KIM THOMAS; KYNE GRAHAM MICHAEL
权利人:PFIZER
摘要:This invention relates to a range of 1-aryl-4-cyclopropylpyrazoles in which the cyclopropyl ring is substituted at the angular position, and pharmaceutically acceptable salts and solvates thereof, to compositions comprising such compounds, processes to their synthesis and their use as parasiticides.