合成目标产物 Propyl Butyrate 主要起始原料 1-Propanol And Butyraldehyde
(文献来源)合成步骤主要原料 1-Propanol 和 Butyraldehyde
Mercury(II) Butyrate置于溴体系中,用 四氯化碳 用作溶剂,化学反应生成丁酸丙酯 参考文献:Ol'Dekop,Yu.A. Et Al.,Journal Of General Chemistry Of The Ussr,1978,Vol. 48,# 7,P. 1456-1459 标题:Ol'Dekop,Yu.A. Et Al.,Journal Of General Chemistry Of The Ussr,1978,Vol. 48,# 7,P. 1456-1459
专利号:US-6177564-B1 优先权日:1998-09-11 标题:Process for the synthesis of N-benzyl-3-(4-fluorophenyl)-1-4-oxazin-2-one 发明人:NELSON TODD D; BHUPATHY MAHADEVAN 权利人:MERCK & CO INC 摘要:The present invention is concerned with a novel process for the preparation of N-benzyl-3-(4-fluorophenyl)-1,4-oxazin-2-one of the formula:This compound is useful as an intermediate in the synthesis of compounds which possess pharmacological activity, in particular, as substance P (neurokinin-1) receptor antagonists.
专利号:US-3887490-A 优先权日:1970-08-27 标 题 :Process for regenerating noble metal catalyst for the synthesis of hydrogen peroxide according to the anthraquinone process 发明人:SCHREYER GERD; THEISSEN FERDINAND; WEIBERG OTTO; WEIGERT WOLFGANG 权利人:DEGUSSA 摘要:In situ regeneration of noble metal catalysts for the synthesis of hydrogen peroxide by the anthraquinone process is provided by employing as the working solution coming from the extraction or desorption step and being introduced into the hydrogenation step a solution which contains at least 250 mg/liter of hydrogen peroxide, to thereby completely regenerate the noble metal catalyst by full capacity of the hydrogenation step.
专利号:US-5663480-A 优先权日:1993-12-20 标题:Synthesis of aromatic carbonates by transesterification using a catalyst comprising a microporous material and a group IV metal 发明人:TSUNEKI HIDEAKI; KIRISHIKI MASARU; WATANABE KENICHI; ONDA YOSHIYUKI 权利人:NIPPON CATALYTIC CHEM IND 摘要:A catalyst for producing an aryl ester of a carbonic or carboxylic acid is disclosed, which includes a microporous material containing a metal element belonging to group IV. This catalyst can be used as a heterogeneous catalyst to produce the aryl ester in high yield with industrial advantages. In order to produce the aryl ester using the catalyst, a carbonate or an aliphatic carboxylate is transesterified with an aromatic hydroxy compound, or an aryl carboxylate is transesterified with a carbonate, or an alkyl aryl carbonate is disproportionated by transesterification.
专利号:US-7078574-B2 优先权日:2001-04-21 标题 :Method for the intrinsically safe handling of 3-chloropropyne 发明人:STAMM ARMIN; KNEUPER HEINZ-JOSEF; RITTINGER STEFAN; DRANSFELD PETER; SCHILDBERG HANS-PETER; HEILIG MANFRED; WEBER THEODOR 权利人:BASF AG 摘要:A method is provided for the intrinsically safe handling of 3-chloropropyne in the presence of a diluent with a boiling point ranging from −50° C. (223 K) to 200° C. (473 K) under atmospheric pressure, wherein the concentration of 3-chloropropyne in the liquid phase and in the gas phase is kept below the concentrations capable of deflagration by means of the type and amount of the diluent, the temperature and the total system pressure, together with the use of a 3-chloropropyne prepared, stored or transported in this way in the synthesis of dyestuffs, pharmaceutical and agricultural active ingredients, electroplating auxiliaries, disinfectants, steroids and growth hormones.
专利号:US-4471123-A 优先权日:1983-04-29 标题:Synthesis of isoxazolyl imidazolidinones 发明人:VARIE DAVID L; LECHLEITER JOHN C 权利人:LILLY CO ELI 摘要:Herbicidal isoxazolyl imidazolidinones are prepared by reaction of an isoxazolyl-allylurea with ozone and reduction.
专利号:US-6927291-B2 优先权日:2001-03-01 标 题:Method for the synthesis of 2′,3′-dideoxy-2′,3′-didehydronucleosides 发明人:JIN FUQIANG; CONFALONE PASQUALE N 权利人:PHARMASSET LTD 摘要:An efficient synthetic route to antiviral 2′,3′-dideoxy-2′,3′-didehydro-nucleosides, such as 2′,3′-dideoxy and 2′- or 3′-deoxyribo-nucleoside analogs, from available precursors is disclosed, with the option of introducing functionality as needed. In one embodiment, a method for the preparation of β-D and β-L-2′,3′-dideoxy-2′,3′-didehydro-nucleosides is described that includes: activating a compound of structure (1) n n nwherein B is a pyrimidine or purine base and Y is O, S or CH 2 with an acyl halide of the formula X—C(â•?O)R 1 , X—C(â•?O)C(R 1 ) 2 OC(â•?O)R 1 or X—C(â•?O)OR 1 (wherein X is a halogen, and each R 1 is independently hydrogen, lower alkyl, alkyl, aryl or phenyl); reducing the resulting compound with a reducing agent to form a 2′,3′-dideoxy-2′,3′-didehydro-nucleoside; and optionally deprotecting the nucleoside. The haloacylation of the first step can form the 2′-acyl-3′-halonucleoside, the 3′-acyl-2′-halonucleoside, or a mixture thereof.
摘要:Food and Cosmetics Toxicology., 2(327), 1964 摘要:Industrial Medicine and Surgery., 41(31), 1972 摘要:Schafer, E. W., Jr., and W. A. Bowles Jr. 1985. Acute oral toxicity and repellency of 933 chemicals to house and deer mice. Archives of Environmental Contamination and Toxicology 14:111-129. https://www.aphis.usda.gov/ws/nwrc/chem-effects-db/S_schafer851.pdf