CAS: 36284-77-2; 3-β-[(O-α-L-Rhamnopyranosyl-(1->2)-α-L-Arabinopyranosyl)Oxy]Olean-12-En-28-Oic Acid O-α-L-Rhamnopyranosyl-(1->4)-β-D-Glucopyranosyl-(1-->6)-β-D-Glucopyranosyl Ester
该化合物是一种主要来自Hedera 螺旋(ivy) 物种的三肢细胞沙邦素,具有显著的生物活动特性,包括抗炎,抗微生物和预期特性,因此与药物和治疗研究有关.在结构上,它具有一种与三肢甘油相连的糖味,有助于其表面活化和膜-相互作用能力.它的行动机制往往涉及移动细胞信号路径,特别是在呼吸道和免疫反应中. Hederasaponin B 因其标准化的研究应用纯度而受到重视,确保研究的再生性.HPLC和LC-MS等分析方法通常用于质量核查.其稳定性和溶解性简介有很好的记录,便于实验使用.
- 英文名称3-β-[(O-α-L-Rhamnopyranosyl-(1->2)-α-L-Arabinopyranosyl)Oxy]Olean-12-En-28-Oic Acid O-α-L-Rhamnopyranosyl-(1->4)-β-D-Glucopyranosyl-(1-->6)-β-D-Glucopyranosyl Ester
- 中文名称刺五加叶中
- IUPAC名称(2S,3R,4S,5S,6R)-6-((((2R,3R,4R,5S,6R)-3,4-dihydroxy-6-(hydroxymethyl)-5-(((2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)tetrahydro-2H-pyran-2-yl)oxy)methyl)-3,4,5-trihydroxytetrahydro-2H-pyran-2-yl (4aS,6aS,6bR,8aR,10S,12aR,12bR,14bS)-10-(((2S,3R,4S,5S)-4,5-dihydroxy-3-(((2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)tetrahydro-2H-pyran-2-yl)oxy)-2,2,6a,6b,9,9,12a-heptamethyl-1,3,4,5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b,13,14b-octadecahydropicene-4a(2H)-carboxylate
- 其它别名Hederasaponin B; 3β-(2-O-α-L-Rhamnopyranosyl-α-L-arabinopyranosyloxy)oleana-12-ene-28-oic acid 6-O-(4-O-α-L-rhamnopyranosyl-β-D-glucopyranosyl)-β-D-glucopyranosyl ester; 3β-[(2-O-α-L-Rhamnopyranosyl-α-L-arabinopyranosyl)oxy]olean-12-en-28-oic acid 6-O-(4-O-α-L-rhamnopyranosyl-β-D-glucopyranosyl)-β-D-glucopyranosyl ester; 3β-[2-O-(α-L-Rhamnopyranosyl)-α-L-arabinopyranosyloxy]oleana-12-ene-28-oic acid 6-O-[4-O-(α-L-rhamnopyranosyl)-β-D-glucopyranosyl]-β-D-glucopyranosyl ester; Saponin PJ3; HEDERASAPONIN B (RG)
- CAS编号36284-77-2
- MFCD编号:MFCD16036216
- 分子式:C59H96O25
- 分子量:1205.38
- 产品CID: 1372284
- 产品分类生物化工 → 提取物
物理性质
MSDS等安全信息
- GHS符号GHS07
- 警示词Warning
- 危险描述H303 May be harmful if swallowed+H313 Skin contact may be harmful+H333 Inhalation may be harmful to the body
- 防范说明P264Thoroughly clean after treatmentP280Wear protective gloves/Wear protective clothing/Wear protective goggles/Wear a protective maskP305If it enters the eyesP351Rinse carefully with water for a few minutesP338Remove the contact lens(If any)And easy to operate,Continue flushingP337If eye irritation persistsP313Obtain medical advice/care
- 安全声明H303May be harmful if swallowed+H313Skin contact may be harmful+H333Inhalation may be harmful to the body
上下游产品
CAS号114906-75-1 ciwujianoside C4合成工艺路线路线简述
- 合成目标产物 Hederasaponin B 主要起始原料 Olean-12-En-28-Oic Acid, 3-[[2-O-(6-Deoxy-α-L-Mannopyranosyl)-α-L-Arabinopyranosyl]Oxy]-, O-6-Deoxy-α-L-Mannopyranosyl-(1->4)-O-6-O-Acetyl-β-D-Glucopyranosyl-(1->6)-β-D-Glucopyranosyl Ester, (3β)-
- (文献来源)合成步骤主要原料 Olean-12-En-28-Oic Acid, 3-[[2-O-(6-Deoxy-α-L-Mannopyranosyl)-α-L-Arabinopyranosyl]Oxy]-, O-6-Deoxy-α-L-Mannopyranosyl-(1→4)-O-6-O-Acetyl-β-D-Glucopyranosyl-(1→6)-β-D-Glucopyranosyl Ester, (3β)-
Ciwujianoside C4置于氢氧化钾体系中,化学反应 24.0H,以26 Mg的收率获得产物刺五加叶中
参考文献:Shao,Chun-Jie; Kasai,Ryoji; Xu,Jing-Da,Chemical And Pharmaceutical Bulletin,1988,Vol. 36,# 2,P. 601-608
标题:Shao,Chun-Jie; Kasai,Ryoji; Xu,Jing-Da,Chemical And Pharmaceutical Bulletin,1988,Vol. 36,# 2,P. 601-608
海关参考信息
- 2901210000-乙烯
2901220000-丙烯
2905122000-异丙醇
2905310000-1,2-乙二醇 - 💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
- 详情请参考：📖 海关编码查询和海关进出口税则
网址: http://www.caoyuankang.cn
电话: 13438890071👤
销售电话:13438890071
邮箱：3003796343@qq.com
电话: 13438890071👤
📞成都草源康生物科技有限公司 ⚠️参考联系方式
销售电话:13438890071
邮箱：3003796343@qq.com
🆔 联系时候可告知是从"百琢研"平台获取的信息.
⚠️ 声明: 该企业未认证、未认领，请自行辨别信息的真实性和可靠性。咨询或交易时请注意风险评估与信息核实，百琢研不参与任何交易。企业认领注册入口→
⚠️ 未注册 · 未认证企业
备注: 📌 数据来源说明：本展台内容基于各搜索引擎等公开数据整理，仅作展示用途。请用户自行辨别 ✉️ 若企业需抹除展台内容或有异议， 请通过页面底部联系方式告知我们，我们会尽快处理。第 1 / 1 页
供应商参考报价(招募中)
品牌试剂参考报价(招募中)
📌 第三方产品分析报告
主要参考文献
1: Song J, Yeo SG, Hong EH, Lee BR, Kim JW, Kim J, Jeong H, Kwon Y, Kim H, Lee S, Park JH, Ko HJ. Antiviral Activity of Hederasaponin B from Hedera helix against Enterovirus 71 Subgenotypes C3 and C4a. Biomol Ther (Seoul). 2014 Jan;22(1):41-6. doi: 10.4062/biomolther.2013.108.
2: Liu J, Yang X, Li L, Zhang Q, Zhang Z, Zhang X, Zhao Y, Yu M, Yu Z. A rapid and sensitive liquid chromatography-tandem mass spectrometric method for the determination of hederasaponin B in rat plasma: Application to a pharmacokinetic study. Asian J Pharm Sci. 2017 Jul;12(4):363-369. doi: 10.1016/j.ajps.2016.09.001. Epub 2016 Sep 22.
3: Liu Q, Zhu XZ, Feng RB, Liu Z, Wang GY, Guan XF, Ou GM, Li YL, Wang Y, Li MM, Ye WC. Crude triterpenoid saponins from Anemone flaccida (Di Wu) exert anti- arthritic effects on type II collagen-induced arthritis in rats. Chin Med. 2015 Jul 25;10:20. doi: 10.1186/s13020-015-0052-y.
合成参考文献
参考文献:10.5281/zenodo.5794106
摘要:The LOTUS Initiative for Open Natural Products Research: frozen dataset union wikidata (with metadata) | DOI:10.5281/zenodo.5794106
📝 需求与反馈
尽可能描述清楚需求与问题信息
