CAS: 3658-80-8; Dimethyltrisulfide

相似化合物

3658-80-8 31499-71-5 3600-24-6

上下游产品

CAS号67-56-1 甲醇 | CAS号74-93-1 甲硫醇 | CAS号624-92-0 二甲基二硫醚 | CAS号74-88-4 碘甲烷 | CAS号3385-94-2 六甲基二硅硫烷 | CAS号13882-12-7 Methyl methanet... | CAS号2949-92-0 甲基硫代磺酸甲酯 | CAS号77-78-1 硫酸二甲酯 | CAS号102391-50-4 potassium S-met... | CAS号512-42-5 硫酸甲酯钠 | CAS号74-93-1 甲硫醇 | CAS号333-20-0 硫氰酸钾 | CAS号5813-48-9 Methanesulfenic... | CAS号30411-03-1 methylsulfanyl ... | CAS号2181-42-2 三甲基碘代磺酸 | CAS号188290-36-0 Thiophene(SIV) | CAS号3326-88-3 3H-1,2-Dithiol-3-one

二甲基二硫置于三苯基硫氯甲烷体系中,用 氯仿 作为反应溶剂,化学反应 2.0H,以88%的收率获得产物二甲基三硫
参考文献:硫原子插入到ss键中-对称的三硫化物的形成
标题:硫原子插入到ss键中-对称的三硫化物的形成
摘要:三苯基甲烷亚磺酰氯(3A)与无环二硫化物4或5的反应以中等至非常好的产率和选择性得到了相应的三硫化物1或2.提出了解释化学反应的机制.
DOI:10.1016/s0040-4039(01)01897-4

专利信息

专利号:US-9802890-B2
优先权日:2006-02-21
标 题 :Processes for the convergent synthesis of calicheamicin derivatives
发明人：MORAN JUSTIN KEITH; GU JIANXIN
权利人:WYETH LLC
摘要:This invention describes processes for the convergent synthesis of calicheamicin derivatives, and similar analogs using bifunctional and trifunctional linker intermediates.

专利号:US-10590158-B2
优先权日:2015-06-29
标题:Total synthesis of shishijimicin A and analogs thereof
发明人：NICOLAOU KYRIACOS C; LI RUOFAN; LU ZHAOYONG; SOHN TE-IK; WOODS JAMES; PITSINOS EMMANOUIL N
权利人:UNIV RICE WILLIAM M
摘要:In one aspect, the present disclosure provides shishijimicin analogs of the formula: wherein the variables are as defined herein. In another aspect, the present disclosure also provides methods of preparing the compounds disclosed herein. In another aspect, the present disclosure also provides pharmaceutical compositions and methods of use of the compounds disclosed herein. Additionally, antibody drug conjugates of the compounds are also provided.

专利号:US-5877296-A
优先权日:1994-06-03
标题:Process for preparing conjugates of methyltrithio antitumor agents
发明人：HAMANN PHILIP ROSS; HINMAN LOIS; HOLLANDER IRWIN
权利人:AMERICAN CYANAMID CO
摘要:This invention describes carrier-drug conjugates prepared from disulfide analogs of the calicheamicin family of potent antitumor antibiotics and their derivatives, as well as similar analogs from related antitumor antibiotics such as the esperamicins. The carrier can be an antibody, growth factor, or steroid which targets an undesired population of cells, such as those of a tumor. Whole protein carriers as well as their antigen-recognizing fragments and their chemically or genetically manipulated counterparts are useful for the targeting portion of the conjugates. This invention includes compounds required for the synthesis of these conjugates, appropriate pharmaceutical compositions of the carrier-drug conjugates, and their method of use.

专利号:US-2018327439-A1
优先权日:2015-06-29
标题:Total synthesis of shishijimicin a and analogs thereof

专利号:US-5739116-A
优先权日:1994-06-03
标题:Enediyne derivatives useful for the synthesis of conjugates of methyltrithio antitumor agents

专利号:US-2007197455-A1
优先权日:2006-02-21
标 题:Processes for the convergent synthesis of calicheamicin derivatives