CAS: 5036-48-6; N-(3-Aminopropyl)-Imidazole

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CAS号288-32-4 咪唑 | CAS号1336-21-6 氨水 | CAS号107-13-1 丙烯腈 | CAS号23996-53-4 N-(2-氰乙基)咪唑 | CAS号110552-32-4 3-(3-imidazol-1... | CAS号112086-52-9 Benzyl-(3-imida... | CAS号820220-10-8 N-(3-imidazol-1... | CAS号794469-52-6 Guanidine,[3-(1... | CAS号90259-60-2 2-amino-N-(3-im... | CAS号90259-73-7 2-amino-5-chlor... | CAS号90260-19-8 N-(3-imidazol-1... | CAS号93668-06-5 N-(3-imidazol-1...

N-(2-氰基乙基)咪唑置于镍 氢气体系中,化学反应生成 1-(3-氨基丙基)咪唑
参考文献:八烷基卟啉的内消旋(甲硫氨酸)官能化
标题:八烷基卟啉的内消旋(甲硫氨酸)官能化
摘要:内消旋-乙酰氧基甲基八烷基卟啉[例如(1),(7)和(8)]与多种亲核试剂反应,例如醇(产生相应的烷氧基甲基卟啉),胺(产生氨基甲基卟啉)和格氏试剂(产生内消旋基团).-烷基卟啉).用硫醇试剂处理内消旋-乙酰氧基甲基卟啉完成还原,得到内消旋-甲基卟啉而不是硫化物.利用这些介观官能化反应,合成了潜在的细胞色素p450模型和血红蛋白紧张形式的模型.
DOI:10.1039/p19810002625

专利信息

专利号:WO-0140193-A1
优先权日:1999-12-03
标题:Method for the synthesis of pyrazolines
发明人：BOLDI ARMEN M
权利人:CHEMRX ADVANCED TECHNOLOGIES I; BOLDI ARMEN M
摘要:The present invention provides a method for the synthesis of compounds of Formula (I). Also claimed are novel intermediates and their methods of synthesis.

专利号:US-2002103381-A1
优先权日:2000-11-30
标 题 :Method for the synthesis of pyrazolines
发明人：BOLDI ARMEN M
摘要:The present invention provides a method for the synthesis of compounds of Formula I: n n n Also claimed are novel intermediates and their methods of synthesis.

专利号:US-7138526-B1
优先权日:1999-06-15
标 题 :Solid phase synthesis of n,n-disubstituted diazacycloalkylcarboxy derivatives
发明人：HERPIN TIMOTHY F; MORTON GEORGE C; SALVINO JOSEPH M
权利人:AVENTIS PHARMA INC
摘要:A method for the solid phase synthesis of N,N-disubstituted diazacycloalkylcarboxy derivatives of general formula (I) and (II) is claimed. Examples include piperazine-2-carboxamide. The method is applicable to the synthesis or large combinatorial libraries

专利号:US-9303056-B2
优先权日:2012-07-25
标题 :Monomer for synthesis of RNA, method for producing same, and method for producing RNA
发明人：KATAOKA MASANORI
权利人:UNIV KOCHI
摘要:The objective of the present invention is to provide a monomer for RNA synthesis which can be efficiently produced and therefore by which the producing cost of RNA can be remarkably decreased, and a method for efficiently producing the monomer in a small number of steps. In addition, the objective of the present invention is also to provide a method by which RNA can be efficiently produced even when a approximately stoichiometry amount of the monomer for RNA synthesis is used. The monomer for RNA synthesis according to the present invention is represented by the following formula (I) or (I′): n nwherein R 1 is a protective group of the hydroxy group and R 2 is an alkyl group or the like.

专利号:US-7109377-B2
优先权日:1996-10-16
标 题:Synthesis of combinatorial libraries of compounds reminiscent of natural products
发明人：SCHREIBER STUART L; SHAIR MATTHEW D; TAN DEREK S; FOLEY MICHAEL A; STOCKWELL BRENT R
权利人:HARVARD COLLEGE
摘要:The present invention provides complex compounds reminiscent of natural products and libraries thereof, as well as methods for their production. The inventive compounds and libraries of compounds are reminiscent of natural products in that they contain one or more stereocenters, and a high density and diversity of functionality. In general, the inventive libraries are synthesized from diversifiable scaffold structures, which are synthesized from readily available or easily synthesizable template structures. In certain embodiments, the inventive compounds and libraries are generated from diversifiable scaffolds synthesized from a shikimic acid based epoxyol template. In other embodiments, the inventive compounds and libraries are generated from diversifiable scaffolds synthesized from the pyridine-based template isonicotinamide. The present invention also provides a novel ortho-nitrobenzyl photolinker and a method for its synthesis. Furthermore, the present invention provides methods and kits for determining one or more biological activities of members of the inventive libraries. Additionally, the present invention provides pharmaceutical compositions containing one or more library members.

专利号:US-6906046-B2
优先权日:2000-12-22
标题 :Pharmaceutical uses and synthesis of benzobicyclooctanes
发明人：JACKSON RANDY W; DARWISH IHAB; BAUGHMAN TED A; HOWBERT J JEFFRY
权利人:CELLTECH R & D INC
摘要:Benzobicyclooctane compounds, their use in inhibiting cellular events involving TNF-α and IL-8, and in the treatment of inflammation events in general; a combinatorial library of diverse bicyclooctanes and process for their synthesis as a library and as individual compounds.