CAS: 636-95-3; (3-Nitrophenyl)Hydrazine Hydrochloride

上下游产品

3-nitro-aniline 4-methoxy-benzaldehyde-(3-nitro-phenylhydrazone) acetone-(3-nitro-phenylhydrazone) 4-Hydroxy-3-{1-[(3-nitro-phenyl)-hydrazono]-ethyl}-chromen-2-one hydroxy-pyruvaldehyde bis-(3-nitro-phenylhydrazone)

间硝基苯胺置于盐酸,Tin(II) Chloride Dihdyrate,Sodium Nitrite体系中,用 水 作为反应溶剂,化学反应 0.5H,以73%的收率获得产物3-硝基苯肼盐酸盐
参考文献:Compositions For Treatment Of Cystic Fibrosis And Other Chronic Diseases
标题:Compositions For Treatment Of Cystic Fibrosis And Other Chronic Diseases
摘要:本发明涉及含有上皮钠通道活性抑制剂与至少一种abc转运蛋白调节剂化合物(a式,B式,C式或d式)的药物组合物.该发明还涉及这些药物配方,以及使用这些组合物治疗cftr介导的疾病,特别是囊性纤维化的方法.

专利信息

专利号:US-11040938-B2
优先权日:2016-07-27
标 题 :Continuous flow process for the synthesis of phenylhydrazine salts and substituted phenylhydrazine salts
发明人：MA BING; PAN SHUAI
权利人:SHANGHAI HYBRID—CHEM TECH; SHANGHAI HYBRID CHEM TECH
摘要:The present invention provided a continuous flow process for the synthesis of phenylhydrazine salts and substituted phenylhydrazine salts. Diazotization, reduction, acidic hydrolysis and salifying with acids are innovatively integrated together. Using acidic liquids of aniline or substituted aniline, diazotization reagents, reductants and acids as raw materials, phenylhydrazine derivative salts is obtained through the synthesis process, which is a three-step continuous tandem reaction including diazotization, reduction, acidic hydrolysis and salifying. The described synthesis process is a kind of integrated solutions, which is carried out in an integrated reactor. The feed inlets of the integrated reactor are continuously filled with raw materials. In the integrated reactor, diazotization, reduction, acidic hydrolysis and salifying are carried out continuously and orderly, and phenylhydrazine salts or substituted phenylhydrazine salts is obtained in the outlet of the integrated reactor without interruption. The total reaction time is no more than 20 min.

专利号:US-11027027-B2
优先权日:2015-01-30
标 题:Pyridazinoindole compounds and methods for PET imaging
发明人：MANNING H CHARLES; CHEUNG YIU-YIN; BUCK JASON R; LI JUN
权利人:UNIV VANDERBILT
摘要:Embodiments of the invention include a novel synthesis of the translocator protein (TSPO) ligands, and methods of imaging a molecular events. Also disclosed are compounds for treatment of diseases, including cancer.

专利号:US-2019152896-A1
优先权日:2016-07-27
标题 :Continuous Flow Process For the Synthesis of Phenylhydrazine Salts and Substituted Phenylhydrazine Salts

专利号:CN-107663161-B
优先权日:2016-07-27
标题:A kind of continuous flow synthesis process of phenylhydrazine salt and substituted phenylhydrazine salt

专利号:CN-107663161-A
优先权日:2016-07-27
标 题 :A kind of continuous flow synthesis process of phenylhydrazine salt and substituted phenylhydrazine salt

专利号:RU-2170737-C2
优先权日:1994-07-11
标 题:Heterobicyclic derivatives, methods of their synthesis and pharmaceutical composition