1,2-二氟苯置于氯磺酸体系中,化学反应 1.0H,以94%的收率获得3,4-二氟苯-1-磺酰氯 参考文献:具有固有微孔性的聚醚砜的合成与表征 标题:具有固有微孔性的聚醚砜的合成与表征 摘要:具有固有微孔性(pim)的聚合物通常是采用螺旋结构的梯型聚合物.在本研究中,合成了一种新的非梯型聚醚砜型pim,其中包含线性砜部分.Brunauer-emmett-teller的测量证实,由于存在尺寸为0.54-0.66 Nm的微孔,因此合成的聚合物具有较高的比表面积(430-590 M 2 G-1).新型pim的固有孔隙率特性归因于砜和苯部分的共振结构.预期将来会使用含有砜或类似官能团的pim合成新的气体分离膜. Doi:10.1039/c6Ra13034H
专利信息
专利号:US-10246411-B2 优先权日:2014-10-29 标 题:(Z)-3,4,5-trimethoxystyrylbenzenesulfonamides as potential anticancer agents 发明人:KAMAL AHMED; RASALA MAHESH; RATNA REDDY CHALLA; BHARATH KUMAR GAJJELA; SASTRY VISWESWARA; BASHA SHAIK ANVER; SANTHOSH REEDY VANGALA 权利人:COUNCIL SCIENT IND RES 摘要:This present invention relates to (Z)-3,4,5-Trimethoxystyrylbenzenesulfonamides of general formula A. The invention also provides the synthesis of (Z)-3,4,5-trimethoxystyrylbenzenesulfonamides useful as potential antitumor agents against human cancer cell lines and a process for the preparation thereof.
专利号:RU-2184110-C2 优先权日:1996-12-23 标 题 :Derivatives of nitromethylthiobenzene, method of their synthesis (versions) and pharmaceutical composition
专利号:RU-2194044-C2 优先权日:1997-10-01 标 题 :Derivatives of benzamidine, method of their synthesis and pharmaceutical composition
专利号:US-7803832-B2 优先权日:2004-03-18 标题 :N-(1-arylpyrazol-4L)sulfonamides and their use as parasiticides 发明人:CRITCHER DOUGLAS JAMES; WALSHE NIGEL DEREK ARTHUR; LAURET CHRISTELLE 权利人:PFIZER; PFIZER PROD INC 摘要:The invention relates to a sulfonamide compound of formula (I) or a pharmaceutically, veterinarily or agriculturally acceptable salt or solvate thereof, where the groups R 1 -R 5 are described in the description, to compositions comprising such compounds, processes for their synthesis and their use as parasiticides.
[参考文献]: Anoir Hfaiedh, Et Al. Palladium-Catalyzed Direct Desulfitative C2 Arylations Of 3-Halo-N-Protected Indoles Using (Hetero)Arenesulfonyl Chlorides. Org Biomol Chem. 2016 Jun 7;14(21):4947-56.
合成参考文献
参考文献:10.1186/s13065-017-0354-5 摘要:Kambappa V, Chandrashekara GK, Rekha ND, Shivaramu PD, Palle K. Synthesis, anti-angiogenic and DNA cleavage studies of novel N-(4-methyl-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)phenyl)piperidine-4-carboxamide derivatives. Chemistry Central Journal. 2017 Nov 30;11(1). doi: 10.1186/s13065-017-0354-5.