CAS: 3251-56-7; 2-Methoxy-4-Nitrophenol

该化合物是属于硝酸蛋白类的有机化合物,具有甲氧基组(-OCH3)和硝酸组(-NO2),分别附于苯球环,特别是2和4个位置;该化合物一般是黄色至橙色晶状固体,以其在有机溶剂中的中等溶解性以及水中的溶解性有限而著称;甲基氧和硝基化合物的存在有助于其独特的化学再活动,使其成为有机合成和各种化学反应的有用中间体.

结构式图片

欧盟法规

ECHA物质ECHA物质化妆品禁用物质清单C&L通报REACH预注册

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CAS号97-52-9 2-甲氧基-4-硝基苯胺 | CAS号7244-73-7 1-ethoxy-2-meth... | CAS号709-09-1 3,4-二甲氧基硝基苯 | CAS号90-05-1 愈创木酚 | CAS号555-03-3 3-硝基苯甲醚 | CAS号136616-34-7 1-piperidino-3-... | CAS号1009-36-5 2-氯-5-硝基苯甲醚 | CAS号877-22-5 2-羟基-3-甲氧基苯甲酸 | CAS号93-27-6 N-(2-甲氧基-4-硝基苯基)乙酰胺 | CAS号3251-55-6 3-甲氧基乙酰氨基苯 | CAS号219785-42-9 4-(2-(二异丙基氨基)乙氧... | CAS号19782-77-5 4-乙氧基-3-甲氧基苯胺 | CAS号709-09-1 3,4-二甲氧基硝基苯 | CAS号52200-90-5 4-氨基-2-甲氧基苯酚 | CAS号3316-09-4 4-硝基儿茶酚 | CAS号315228-80-9 Benzenethiol, 2... | CAS号16766-30-6 4-氯-2-甲氧基苯酚 | CAS号7417-89-2 2-(4-氯-2-羟基苯氧基)乙酸 | CAS号75813-77-3 N-[4-(乙酰氧基)-3-甲...

合成工艺路线路线简述

    木榴油置于硝酸,溶剂黄146体系中,用 乙腈 作为反应溶剂,以16%的收率获得产物4-硝基愈创木酚
    参考文献:氟化物诱导的通过聚乙二醇链连接的双苯乙烯基硫脲的分子间受激准分子的形成
    标题:氟化物诱导的通过聚乙二醇链连接的双苯乙烯基硫脲的分子间受激准分子的形成
    摘要:由聚乙二醇(peg)链,连接新bispyrenyl硫脲l1-L3,和甲氧苯硫脲芘,L4,合成.当与f结合-在chcl 3,L1-L3表现出强准分子发射带(我ë)和弱单体发射带(我中号),而l4显示两频带的相同的强度.但是,在荧光光谱观测到很少或没有变化l1在添加oh-,Aco-,Bzo-,H 2 Po 4-,氯-,溴-和我-.因此,仅f-诱导的芘受激准分子的形成.作业的地块表现出1/1或2/2络合l1为f-.的比率我ë /我中号的l1 .女-复杂都依赖于浓度l1,这意示二聚l1经由分子间形成受激准分子进行.间l1-L4,L1具有朝向f中的最高的结合常数和灵敏度-暗示连接peg链的重要性.l1被证明是适用于f优异的探针-在chcl 3与检测限为46.2微克/升.
    DOI:10.1016/j.Tet.2011.08.060

    海关参考信息

    专利信息


    专利号:WO-2007139998-A2
    优先权日:2006-05-25
    标题:Synthesis of a compound which is a suitable intermediate in the synthesis of oxindoledioxane derivatives

    专利号:US-8067460-B2
    优先权日:2004-10-04
    标 题 :5-phenoxyalkoxypsoralens and methods for selective inhibition of the voltage gated Kv1.3 potassium channel
    发明人:WULFF HEIKE; SANKARANARAYANAN ANANTHAKRISHNAN; HAENSEL WOLFRAM; SCHMITZ ALEXANDER; SCHMIDT-LASSEN KRISTINA
    权利人:WULFF HEIKE; SANKARANARAYANAN ANANTHAKRISHNAN; HAENSEL WOLFRAM; SCHMITZ ALEXANDER; SCHMIDT-LASSEN KRISTINA; UNIV CALIFONIA
    摘要:Compositions of matter comprising 5-phenoxyalkoxypsoralen compounds and their method of synthesis and use. The compounds are useable to treat diseases or disorders in human or animal subjects, including autoimmune diseases. The compounds inhibit potassium channels, including the Kv1.3 channel and at least some of the therapeutic effects of such compounds may be due at least in part to potassium channel inhibition. In some embodiments, the compounds are more selective for certain potassium channels (e.g., Kv1.3 channels) than other potassium channels (e.g., Kv1.5 channels).

    专利号:CA-2640585-A1
    优先权日:2003-02-05
    标题 :Synthesis of 2-butyl-3-(2'-(1-trityl-1h-tetrazol-5-yl)biphenyl-4-yl)-1,3-diazaspirol{4,4}-non-ene-4-one

    专利号:WO-2004096171-A1
    优先权日:2003-04-29
    标题 :Skin whitening cosmetic composition comprising the extract of machilus thunbergii and the compounds isolated therefrom
    发明人:SON JONG-KEUN; LEE SEUNG-HO; CHANG HYEUN-WOOK
    权利人:YEUNGNAM EDUCATIONAL FOUND; SON JONG-KEUN; LEE SEUNG-HO; CHANG HYEUN-WOOK
    摘要:The present invention is related to a cosmetic composition comprising the extract of Machilus thunbergii and lignan compounds isolated therefrom having potent inhibitory effect on melanin synthesis. Inventive composition shows the excellent inhibitory activity on cultured B-16 melanoma cell therefore, it can be useful in skin whitening cosmetic composition as an cream, skin, lotion, pack and the like.

    专利号:US-2008242662-A1
    优先权日:2005-05-31
    标题 :Organic Compounds
    发明人:NIHONYANAGI ATSUKO; TOYAO ATSUSHI; IWAKI YUKI; MASUYA KEIICHI
    权利人:NIHONYANAGI ATSUKO; TOYAO ATSUSHI; IWAKI YUKI; MASUYA KEIICHI
    摘要:The invention relates to substituted 3,4- or higher substituted piperazine compounds, the use thereof for the preparation of a pharmaceutical formulation for the treatment of a disease that depends on activity of renin; the use of a compound of that class in the treatment of a disease that depends on activity of renin; these compounds for use in the diagnostic and therapeutic treatment of a warm-blooded animal, especially for the treatment of a disease (=disorder) that depends on activity of renin; pharmaceutical formulations or products comprising said compounds, and/or a method of treatment comprising administering said compounds, a method for the manufacture of said compounds as well as novel intermediates, starting materials and/or partial steps for their synthesis. The compounds are especially of the formula I, n n n n n n n n n n wherein R1, R2, R11, C, E and D are as defined in the specification.

    专利号:US-7579356-B2
    优先权日:2005-05-04
    标 题:Thia-tetraazaacenaphthylene kinase inhibitors
    发明人:BATTISTA KATHLEEN A; BIGNAN GILLES C; CONNOLLY PETER J; HAYDEN STUART; JOHNSON SIGMOND G; LIN RONGHUI; PANDEY NIRANJAN B; POWELL MARK T
    权利人:JANSSEN PHARMACEUTICA NV
    摘要:The present invention is directed to novel thia-tetraazaacenaphthylene compounds of Formula (I): n nand pharmaceutically acceptable forms thereof and their synthesis and use as inhibitors of ATP-protein kinase interactions.
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    摘要:S13 | EUCOSMETICS | Combined Inventory of Ingredients Employed in Cosmetic Products (2000) and Revised Inventory (2006) | DOI:10.5281/zenodo.2624118
    摘要:J. Sunkel and H. Staude, Ber. Bunsenges. Physik. Chem. 72, 567 (1968).
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