CAS: 40843-25-2; Diclofop

该化合物是一种选择性除草剂,主要用于控制各种作物,特别是谷物中的年草和某些大叶杂草,它属于丙氧基丙酰丙丙烯酸化学类,其作用是抑制对植物脂肪酸合成至关重要的酶乙酰-CoA 碳酸乙烯酶,Dicolofop通常在植物出现后应用,允许其针对积极种植的杂草,同时尽量减少对成熟作物的伤害.该物质的特点在于它对哺乳动物和鸟类的毒性相对较低,但可能对水生生物有害,需要谨慎地处理和应用以防止环境污染.其效力受到应用时间,环境条件和现有特定杂草物种等因素的影响.与许多除草剂一样,抗药管理战略对于保持其效力十分重要.应当始终遵循适当的使用准则和安全防范措施,以减少其应用的潜在风险.

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CAS号40843-73-0 4-(2,4-二氯苯氧基)苯酚 | CAS号598-78-7 2-氯丙酸 | CAS号17639-93-9 2-氯丙酸甲酯 | CAS号51338-27-3 禾草灵 | CAS号64855-76-1 2-[4-(2,4-dichl...

合成工艺路线路线简述

    4-(2,4-二氯苯氧基)苯酚置于sodium Hydroxide,Potassium Carbonate体系中,用 甲醇,丙酮 作为反应溶剂,化学反应 22.5H,反应生成 禾草灵
    参考文献:Nestler,Hans Juergen; Bieringer,Hermann,Zeitschrift Fur Naturforschung,Teil B: Anorganische Chemie,Organische Chemie,1980,Vol. 35,# 3,P. 366-371
    标题:Nestler,Hans Juergen; Bieringer,Hermann,Zeitschrift Fur Naturforschung,Teil B: Anorganische Chemie,Organische Chemie,1980,Vol. 35,# 3,P. 366-371

    海关参考信息

    专利信息


    专利号:WO-2024256370-A1
    优先权日:2023-06-13
    标 题 :Synthesis of glufosinate using an amidase-based process
    发明人:ZIMMERMANN GUNTHER; POTT MORITZ STEFAN
    权利人:BASF SE
    摘要:The present invention relates to a method of preparing glufosinate, comprising the steps of hydrolysing an N-carbamoyl glufosinate amide with an Amidase enzyme to form an N- carbamoyl amino acid compound followed by cleaving off the carbamoyl moiety of said N- carbamoyl amino acid compound.

    专利号:US-2025120400-A1
    优先权日:2021-12-10
    标题:Synthesis of glufosinate using a hydantoinase-based process
    发明人:DITRICH KLAUS; BREUER MICHAEL; POTT MORITZ STEFAN; ZIMMERMANN GUNTHER; SEEMAYER STEFAN
    权利人:BASF SE
    摘要:The present invention relates to a method of manufacturing glufosinate, comprising the steps of hydrolysing a hydantoin with a Hydantoinase enzyme to form a N-carbamoyl amino acid compound followed by cleaving off the carbamoyl moiety of said N-carbamoyl amino acid compound.

    专利号:US-7119232-B2
    优先权日:2004-03-26
    标题 :Nucleophilic substitution reactions of difluorormethyl phenyl sulfone with alkyl halides leading to the facile synthesis of terminal 1,1-difluoro-1-alkenes and difluoromethylalkanes
    发明人:PRAKASH G K SURYA; HU JINBO; OLAH GEORGE A; WANG YING
    权利人:UNIV SOUTHERN CALIFORNIA
    摘要:(Benzenesulfonyl)difluoromethyl anion, in situ generated from difluoromethyl phenyl sulfone and a base, was found to easily undergo nucleophilic substitution reactions (S N 2) with primary alkyl halides, elemental halogens, and perfluoroalkyl halides with good selectivity. The formed (benzenesufonyl)difluoromethylalkanes are useful intermediates for the facile preparation of 1,1-difluoro-1-alkenes and difluoromethylalkanes. Thus, difluoromethyl phenyl sulfone acts as both “CF 2 â•?â€? and “CF 2 H − â€? synthons

    专利号:US-11919928-B2
    优先权日:2016-03-16
    标题 :Method for producing dihydrotentoxin
    发明人:KUBO TAKASHI; MACHIDA MASAYUKI; FUJIOKA TOMONORI; YAMAGUCHI Shigenari; KAWAI KIYOSHI
    权利人:KUMIAI CHEMICAL INDUSTRY CO
    摘要:An object of the present invention is to identify an enzyme having activity of synthesizing dihydrotentoxin that is a tentoxin precursor and an enzyme having activity of synthesizing tentoxin using dihydrotentoxin as a substrate. The present invention concerns a tentoxin synthesis-related gene encoding a protein comprising the amino acid sequence of SEQ ID NO: 16 and having activity of nonribosomal peptide synthesis of dihydrotentoxin and a tentoxin synthesis-related gene encoding a protein comprising the amino acid sequence of SEQ ID NO: 18 and having activity of converting dihydrotentoxin to tentoxin.

    专利号:US-5614551-A
    优先权日:1994-01-24
    标题:Inhibitors of fatty acid synthesis as antimicrobial agents
    发明人:DICK JAMES D; KUHAJDA FRANCIS P
    权利人:UNIV JOHNS HOPKINS
    摘要:Fatty acid synthase (FAS) is overexpressed by certain infectious organisms that are resistant to most currently available antibiotics. Contrarywise, little FAS expression is identified in patient tissues. Inhibition of fatty acid synthesis is thus selectively toxic to invasive cells, while patient cells with low FAS activity are resistant. This invention provides a method of treating septic patients where fatty acid synthesis by invading cells is inhibited with resultant interruption of the disease process.

    专利号:US-5877186-A
    优先权日:1997-04-28
    标题 :Carotenoid synthesis inhibiting herbicides and fatty acid synthesis inhibiting oxime herbicides as anti-apicomplexa protozoan parasite agents
    发明人:LEEF JAMES L; CARLSON PETER S
    权利人:PARAPRO LLC
    摘要:Protozoan parasites of the phylum Apicomplexa include some of the most important causative agents of human and animal diseases, in particular, malaria. The discovery that an organelle found inside parasites of this phylum probably stems from a plastid of plant origin has stimulated research on the effect of chemical herbicidal agents on Apicomplexa. Members of the triazine family and of the dinitroaniline family of herbicides have been found to be active against some Apicomplexa. The present invention extends the list of chemical herbicidal agents active against Apicomplexa to include classes of herbicides active as carotenoid synthesis inhibitory agents in plants and herbicidal agents effective against fatty acid synthesis in plants.
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    主要参考文献

    1. Qian H, Zhu Y, Chen S, et al. Interacting effect of diclofop-methyl on the rice rhizosphere microbiome and denitrification. Pestic Biochem Physiol. 2018;146:90-96. doi:10.1016/j.pestbp.2018.03.002

    合成参考文献


    参考文献:10.1021/es903755n
    摘要:Diao J, Xu P, Wang P, Lu Y, Lu D, Zhou Z. Environmental behavior of the chiral aryloxyphenoxypropionate herbicide diclofop-methyl and diclofop: enantiomerization and enantioselective degradation in soil. Environ Sci Technol. 2010 Mar 15;44(6):2042–7. doi: 10.1021/es903755n.
    参考文献:10.3390/ijerph8062320
    摘要:Hohenadel K, Harris SA, McLaughlin JR, Spinelli JJ, Pahwa P, Dosman JA, Demers PA, Blair A. Exposure to multiple pesticides and risk of non-Hodgkin lymphoma in men from six Canadian provinces. Int J Environ Res Public Health. 2011 Jun;8(6):2320–30.
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