CAS: 1184-85-6; N-Methylmethane Sulfonamide

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CAS号124-63-0 甲基磺酰氯 | CAS号74-89-5 氨基甲烷 | CAS号121-44-8 三乙胺 | CAS号593-51-1 一甲胺盐酸盐 | CAS号918-05-8 N,N-二甲基甲磺酰胺 | CAS号27238-06-8 N-benzyl-N-meth... | CAS号289042-11-1 瑞舒伐他汀中间体Z-6 | CAS号100868-76-6 N-甲基-N-(吡啶-2-基)甲烷磺酰胺 | CAS号73161-37-2 N-(3-氰基吡啶-2-基)-... | CAS号73161-38-3 1-METHYL-2,2-DI... | CAS号82670-28-8 N-(chloromethyl... | CAS号68984-87-2 N-methyl-N-meth... | CAS号93501-65-6 N-[butan-2-ylsu... | CAS号44637-63-0 N-ethenyl-N-met...

甲基磺酰氯置于甲胺体系中,化学反应生成N-甲基甲磺酰胺
参考文献:Certain N-(R-Sulfonyl) Phosphonamidothioates And Dithioates
标题:Certain N-(R-Sulfonyl) Phosphonamidothioates And Dithioates
摘要:式##str1##的化合物,其中符号具有指定的含义,并且它们作为杀虫剂和/或杀螨剂的用途.

专利信息

专利号:US-9688644-B2
优先权日:2009-04-30
标 题 :Synthesis of Tetracyclines and intermediates thereto
发明人：MYERS ANDREW G; KUMMER DAVID A; LI DERUN; HECKER EVAN; DION AMELIE; WRIGHT PETER M
权利人:HARVARD COLLEGE
摘要:The tetracycline class of antibiotics has played a major role in the treatment of infectious diseases for the past 50 years. However, the increased use of the tetracyclines in human and veterinary medicine has led to resistance among many organisms previously susceptible to tetracycline antibiotics. The recent development of a modular synthesis of tetracycline analogs through a chiral enone intermediate has allowed for the efficient synthesis of novel tetracycline analogs never prepared before. The present invention provides more efficient routes for preparing the enone intermediate and allows for substituents at positions 4a, 5, 5a, and 12a of the tetracycline ring system.

专利号:US-9085538-B2
优先权日:2010-07-26
标题:Process for the preparation of key intermediates for the synthesis of statins or pharmaceutically acceptable salts thereof
发明人：CASAR ZDENKO; STERK DAMJAN; JUKIC MARKO
权利人:CASAR ZDENKO; STERK DAMJAN; JUKIC MARKO; LEK PHARMACEUTICALS
摘要:The invention relates to commercially viable process for the synthesis of key intermediates for the preparation of statins, in particular Rosuvastatin and Pitavastatin or respective pharmaceutically acceptable salts thereof. A new simple and short synthetic route for key intermediates is presented which benefits from the use of cheap and readily available starting materials, by which the conventionally most frequently used DIBAL-H as reducing agent can be avoided.

专利号:US-11198684-B2
优先权日:2017-07-28
标 题 :Intermediates useful for the synthesis of a selective inhibitor against protein kinase and processes for preparing the same
发明人：OH SANG-HO; KHOO JA-HEOUK; LIM JONG-CHUL; LEE DOO-BYUNG; LEE JUNG-AE; LEE JUN-SUP; JU HYUN; SHIN WOO-SEOB; JEON SANG-SEOL
权利人:YUHAN CORP
摘要:The present invention provides intermediates useful for the synthesis of an aminopyrimidine derivative or pharmaceutically acceptable salt thereof having a selective inhibitory activity against protein kinases, especially against the protein kinases for mutant epidermal growth factor receptors; and processes for preparing the same. And also, the present invention provides novel intermediates useful for said process and processes for preparing the same.

专利号:US-8710210-B2
优先权日:2010-06-30
标题:Method of using N-thio compounds for oligonucleotide synthesis
发明人：HE YIGANG; SOROKIN VICTOR; MAZUR WIESLAW ADAM
权利人:HE YIGANG; SOROKIN VICTOR; MAZUR WIESLAW ADAM; GIRINDUS AMERICA INC
摘要:A method for synthesizing an oligonucleotide which comprises using a sulfurizing agent of general formula (I) for sulfurizing at least one phosphorus internucleotide linkage of a precursor of the oligonucleotide, wherein R is an aryl group or a heteroaryl group, which is bonded to the S-atom through an annular carbon atom; and R 1 and R 2 are independently organic residues, preferably a C1-C20 hydrocarbon residue. The method may further comprise purifying the oligonucleotide. Also included is a process for the synthesis of the sulfurizing agent.

专利号:WO-2007074391-A3
优先权日:2005-12-28
标 题 :Preparation of a key intermediate in the synthesis of rosuvastatin
发明人：KHAMAR BAKULESH MAFATLAL; MODI INDRAVADAN AMBALAL; VENKATRAMAN JAYARAMAN; RAVI PONNAIAH; DESAI SANJAY JAGADISH; RAJPUT AMARSINGH L
权利人:KHAMAR BAKULESH MAFATLAL; MODI INDRAVADAN AMBALAL; VENKATRAMAN JAYARAMAN; RAVI PONNAIAH; DESAI SANJAY JAGADISH; RAJPUT AMARSINGH L
摘要:The present invention discloses a novel process to prepare a compound of formula (IIA) by reacting a compound of formula-[D], wherein R1 is C1 to C6 alkyl and R2 is C1 to C8 n-alkyl or branched alkyl, cycloalkyl, phenyl, benzyl or substituted phenyl group; with N-methyl methanesulfonamide and a base, optionally with a salt of N-methyl methanesulfonamide, in suitable solvent(s), to give a compound of formula (IIA), followed by converting compound of formula (IIA) to a compound for formula -[B], by a known process and finally converting a compound of formula (B) to a compound of formula (II), by a novel process using calcium hypochlorite / TEMPO as an oxidant.

专利号:US-9365494-B2
优先权日:2008-12-18
标 题 :Process for synthesis of amino-methyl tetralin derivatives
发明人：DURKIN KIERAN; FISHER LAWRENCE EMERSON; MEILI ARTHUR; SCALONE MICHAELANGELO; SHI XIANQING; VITALE JUSTIN
权利人:DURKIN KIERAN; FISHER LAWRENCE EMERSON; MEILI ARTHUR; SCALONE MICHAELANGELO; SHI XIANQING; VITALE JUSTIN; ROCHE PALO ALTO LLC
摘要:Methods for producing a compound of formula k1 or k2 n nby reducing a dihydronapthalene amide compound of formula in n nwith hydrogen gas in the presence of a ruthenium catalyst of formula j1 or j2n nRu(Z) 2 (L)  j1;n nRu(E)(E′)(L)(D)  j2;n nwherein m, n, Ar, Y, R 1 E, E′, D, Z and L are as defined herein.