CAS: 6515-58-8; 3-(Bromomethyl)Benzoic Acid

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CAS号99-04-7 间甲基苯甲酸 | CAS号614-45-9 过氧化苯甲酸叔丁酯 | CAS号128-08-5 N-溴代丁二酰亚胺 | CAS号99-36-5 3-甲基苯甲酸甲酯 | CAS号120-33-2 3-甲基苯甲酸乙酯 | CAS号62290-17-9 3-溴甲基苯甲酸乙酯 | CAS号75-25-2 三溴甲烷 | CAS号7726-95-6 溴素 | CAS号5689-33-8 3-氰甲基苯甲酸 | CAS号180863-55-2 3-(((叔丁氧基羰基)氨基)... | CAS号226070-69-5 (3-羟基甲基-苄基)-羧酸叔丁酯 | CAS号82072-22-8 3-溴甲基苯甲醇 | CAS号62290-17-9 3-溴甲基苯甲酸乙酯 | CAS号619-21-6 3-羧基苯甲醛 | CAS号121-91-5 间苯二甲酸(IPA) | CAS号117445-22-4 3-(N-B°C-氨甲基)苯甲酸 | CAS号32194-76-6 3-(甲氧基甲基)苯甲酸 | CAS号1129-28-8 3-溴甲基苯甲酸甲酯

3-甲基苯甲酸甲酯置于n-溴代丁二酰亚胺(Nbs)体系中,化学反应生成 3-溴甲基苯甲酸
参考文献:"半不稳定的"钳型配合物的亲核去配位和亲电再生:形成不带有稳定pi受体的阴离子二烷基,二芳基和二氢化物pt(II)配合物.
标题:"半不稳定的"钳型配合物的亲核去配位和亲电再生:形成不带有稳定pi受体的阴离子二烷基,二芳基和二氢化物pt(II)配合物.
摘要:基于新型"长臂"半不稳定pcn型配体c6H4 [ch2P(tbu)2](ch2)2N(ch3)2的新型阴离子二烷基,二芳基和二氢化铂(II)配合物,通式为li + [pt (pcn)(R)2]-(r = Me(4),Ph(6)和h(9))是通过[pt(pcn)(R)]配合物(从相应的氯化物获得)与由于螯合环的打开,相当于rli.基于其他金属的烷基化剂产生的稳定性较差.这些阴离子d8络合物虽然没有稳定的pi受体,但具有热稳定性.它们的特征在于1H,31P [1H],13C和7Li NMR光谱;配合物9的特征还在于单晶x射线晶体学,表明li +离子与开放胺臂的氮原子和相邻分子(h-Li = 2.15 A)的氢化物配体(反应为p原子)配位,从而形成二聚结构.配合物4和9显示出高的亲核反应性,在其上可反应生成钳状配合物.4与水,甲基碘和碘苯的反应分别反应生成中性络合物[pt(pcn)(ch3)](3)和甲
DOI:10.1002/chem.200400514

专利信息

专利号:US-5712367-A
优先权日:1989-10-02
标 题:Process for the solubilization of peptides and process for peptide synthesis
发明人：BERNARD JEAN-MARIE; BOUZID KAMEL; GERVAIS CHRISTIAN
权利人:RHONE POULENC CHIMIE
摘要:A process is disclosed for making peptides soluble in a water-immiscible organic solvent, comprising linking a lipophilic group with an amide or ester bond to the terminal carboxyl group of said peptide; when the lipophilic group is linked to L-serine, a molecule is obtained with a solubility in water at 25 DEG C. of less than 30 g/liter. This lipophilic group is non-polymeric and chemically defined. A process is also disclosed for the synthesis of peptides, optionally protected, in a liquid medium, wherein the starting material is an amino acid or peptide made soluble in an organic medium by a lipophilic group A-L linked to the carboxyl function of the starting amino acid or peptide, and are added to amino acids or peptides to be condensed which are activated on their acid function and protected on their amine function and are optionally protected on their side chain. The peptides resulting from the synthesis are used, where appropriate, for the synthesis of medicinal products, vaccines or agri-foodstuff or plant-protection.

专利号:WO-2015058868-A1
优先权日:2013-10-25
标题 :Compositions and methods for the treatment of cancer
发明人：JIMENO DOÑAQUE JOSÉ Mª
权利人:PANGAEA BIOTECH S L
摘要:The invention relates to anti-tumor compounds which have been designed to functionally disrupt the cross-talk between AEG-1 and the p65 subunit of NF-κB. Therefore, the invention relates to methods and compositions for the treatment of cancer using the compounds identified in the present invention, as well as compositions adequate for sustained release of the compounds of the invention to be administered to the surgical site after resection of the tumor. The invention also provides methods for the synthesis of the compounds of the invention.

专利号:US-9156840-B2
优先权日:2010-06-18
标题:D2 antagonists, methods of synthesis and methods of use
发明人：LUEHR GARY W; SUNDARAM ARATHI; JAISHANKAR PRIYADARSHINI; PAYNE PHILIP W; DRUZGALA PASCAL
权利人:ALTOS THERAPEUTICS LLC
摘要:Provided are D 2 or D 3 antagonist compounds and pharmaceutical compositions of formula I n nand pharmaceutically acceptable salts thereof, or isomers thereof, wherein R 1 , R 2 and R 3 are as defined herein. The invention further comprises methods for making the compounds of the invention and methods for the treatment of conditions mediated by the dopamine D 2 or D 3 receptor from the compounds of the invention.

专利号:CN-114805120-A
优先权日:2022-05-23
标 题:A kind of synthesis technique of methyl m-cyanomethyl benzoate

专利号:US-2014350005-A1
优先权日:2010-06-18
标题 :D2 antagonists, methods of synthesis and methods of use

专利号:WO-2011160084-A1
优先权日:2010-06-18
标题:D2 antagonists, methods of synthesis and methods of use