CAS: 7558-80-7; Sodium Dihydrogenphosphate (Granular)

专利信息

专利号:US-7247752-B2
优先权日:2004-10-01
标 题 :Methods for the synthesis of astaxanthin
发明人：LOCKWOOD SAMUEL F; TANG PENG CHO; NADOLSKI GEOFF; JACKSON HENRY L; FANG ZHIQIANG; DU YISHU; YANG MIN; GEISS WILLIAM; WILLIAMS RICHARD; BURDICK DAVID
权利人:CARDAX PHARMACEUTICALS INC
摘要:A method used for synthesizing intermediates for use in the synthesis of carotenoids and carotenoid analogs, and/or carotenoid derivatives. In some embodiments, the invention includes methods for synthesizing optically active intermediates useful for the synthesis of optically active carotenoids. Synthesis of optically active carotenoids, in one embodiment, may be accomplished by forming an optically active dihydroxy intermediate from ketoisopherone. The optically active dihydroxy intermediate may be converted into optically active astaxanthin derivatives.

专利号:US-9409153-B2
优先权日:2007-12-28
标题:Supported Mo—O—K—MexOy catalyst for the synthesis of methanethiol from high H2S-containing syngas
发明人：YANG YIQUAN; HAO YINGJUAN; CHEN AIPING; WANG QI; YANG LINGMEI; LI QIAOLING; DAI SHENJUN; FANG WEIPING; BARTH JAN-OLAF; WECKBECKER CHRISTOPH; HUTHMACHER KLAUS
权利人:YANG YIQUAN; HAO YINGJUAN; CHEN AIPING; WANG QI; YANG LINGMEI; LI QIAOLING; DAI SHENJUN; FANG WEIPING; BARTH JAN-OLAF; WECKBECKER CHRISTOPH; HUTHMACHER KLAUS; EVONIK DEGUSSA GMBH
摘要:This invention is related to a preparation method of a supported catalyst Mo—O—K-Me x O y for the synthesis of methanethiol from H 2 S-containing syngas. The catalyst comprises of an active component of Mo—O—K-based species, an active promoter and a support denoted as metal (or metals)-carrier. The support is prepared by electroless plating method in such a way that the metal or metals chosen are plated onto the surface of the carrier. Transition metal, especially Fe, Co or Ni are selected to be the plating metal, while SiO 2 , Al 2 O 3 or TiO 2 are selected to be carrier. The catalyst thus prepared is found to be efficient for the synthesis of methanethiol from H 2 S-containing syngasor carbon oxides/hydrogen mixtures, especially regarding a minor formation of the by-product CO 2 .

专利号:WO-2012001578-A1
优先权日:2010-06-29
标 题 :Single-step synthesis of iron oxide nanoparticles
发明人：BURDINSKI DIRK; HAEX NICOLE PETRONELLA MARTIEN
权利人:KONINKL PHILIPS ELECTRONICS NV; BURDINSKI DIRK; HAEX NICOLE PETRONELLA MARTIEN
摘要:The invention provides methods for the synthesis of iron oxide nanoparticles and the particles obtainable by these methods. The particles can be used as tracer materials for magnetic particle imaging and for Magnetic Particle Spectroscopy (MPS). The method for the synthesis of these particles comprises the steps: (i) dissolving at least one water-soluble iron salt and at least one water-soluble stabilizer in water to form a reaction batch, (ii) adding at least one base to the reaction batch to yield a pH of 10 to 13, and (iii) exposing the reaction batch to a reaction temperature T R for a defined period of time DT, wherein T R ≥ 110°C, to obtain the iron oxide nanoparticles.

专利号:US-12281348-B2
优先权日:2020-11-08
标 题:Method for the continuous flow synthesis of (R)-4-halo-3-hydroxy-butyrate
发明人：CHEN FENER; CHENG DANG; HUANG ZEDU; LIU MINJIE; HUANG HUASHAN; JIANG MEIFEN; WANG LULU
权利人:UNIV FUDAN
摘要:This application relates to organic synthesis, and more particularly to a method for the continuous flow synthesis of (R)-4-halo-3-hydroxy-butyrate using a micro-reaction system. This application performs an enzymatic asymmetric reduction of a substrate solution containing halogenated acetoacetate and a biocatalyst solution in the micro-reaction system composed of a micro-mixer, a micro-channel reactor, and a pH regulator to obtain the (R)-4-halo-3-hydroxy-butyrate. Compared to the prior art, the reaction time of the method is only a few minutes, the yield of the product (R)-4-halo-3-hydroxy-butyrate is greater than 95%, the reaction process is continuous, the degree of automation is high, the efficiency is high, and the process is simple to operate and easy to be used in industrialized production.

专利号:WO-2025078505-A1
优先权日:2023-10-13
标 题 :One pot gmp scalable production method for the synthesis of dextran-guanidine-bisphosphonate conjugate
发明人：HOLMBERG ANDERS R
权利人:DEXTECH MEDICAL AB
摘要:The disclosure relates to a large scale GMP synthesis of a modified dextran conjugate, and more particularly to a dextran-guanidine-bisphosphonate conjugate wherein the bisphosphonate is an alendronate group. The disclosure relates to a large scale GMP synthesis that produces high purity, pharmaceutical grade dextran-guanidine-bisphosphonate conjugate. The present disclosure further concerns the use of said dextran-guanidine-bisphosphonate conjugate in medicines treating tumors.

专利号:US-11987826-B2
优先权日:2020-01-21
标 题:Nitrilase mutant and application thereof in the synthesis of an anti-epileptic drug intermediate
发明人：XUE YAPING; XIONG NENG; Lv Peijin; ZHENG YUGUO
权利人:UNIV ZHEJIANG TECHNOLOGY
摘要:The present invention provides a nitrilase mutant protein with increased thermal stability and its application in the synthesis of an anti-epileptic drug intermediate, wherein the mutant is obtained by mutating one or two of the amino acids at position 151, 223 and 250 of the amino acid sequence shown in SEQ ID No. 2. the thermal stability of the nitrilase mutant AcN-T151V/C223A/C250G was increased by up to 1.73 folds. The yield of the final product was up to 95% using the recombinant Escherichia coli containing the nitrilase mutant to hydrolyze 1M 1-cyanocyclohexylacetonitrile to produce 1-cyanocyclohexyl acetic acid at 35° C. And the yield of the final product was up to 97% when hydrolyzing 1.2M 1-cyanocyclohexylacetonitrile at 35° C. The final yield was up to 80% when using the nitrilase mutants obtained by the present invention to synthesize gabapentin.