CAS: 10284-63-6; (1R,2S,3R,4S,5S,6S)-6-Methoxycyclohexane-1,2,3,4,5-Pentaol

上下游产品

quebrachitol methyl 2,3,4-tri-O-benzyl-D-glucopyranoside (4S,5R,6S)-4,5,6-tris-benzyloxycyclohex-2-en-1-one 1-O-Allyl-2,3,4-tri-O-benzyl-D-chiro-inositol2,3,4,5,6-Penta-O-acetyl-1-O-methyl-myo-inositol (1R,2S,3R,4R,5S,6S)-1-Methoxy-2,3,4,5,6-pentakis-trimethylsilanyloxy-cyclohexane R)-2r,3c,4t,6t-tetrahydroxy-5c-methoxy-cyclohexanone(2R)-2r,3c,4t,6t-tetrahydroxy-5c-methoxy-cyclohexanone 3-O-methyl-1,2:5,6-bis-O-(1-methylethylidene)-D-chiro-inositol

(1R,2R,3R,4S,5R,6S)-2,3,6-Trihydroxy-4,5-Di-O-Isopropylidene-1-O-Methylcyclohexane置于盐酸体系中,用 水,丙酮 用作溶剂,化学反应生成D-松醇
参考文献:Efficient And Enantiodivergent Synthesis Of (+)-And (-)-Pinitol
标题:Efficient And Enantiodivergent Synthesis Of (+)-And (-)-Pinitol
摘要:
Doi:10.1021/ja00181A081

专利信息

专利号:US-5516950-A
优先权日:1994-04-15
标 题:Method for the production of D-chiroinositol
发明人：PICCARIELLO THOMAS; SAMANARYKE GAMINI
权利人:INSMED PHARM INC
摘要:The present invention relates to the synthesis of D-chiroinositol from a dialdose, comprising the steps of condensing the dialdose by an acyloin condensation reaction to form an inosose, protecting the carbon atoms at the 2, 3, 4 and 5 positions, reducing the ketone of the inosose and removing the protecting groups. In addition, a method of preparing mannodialdose from mannuronic acid is disclosed.

专利号:US-2024279231-A1
优先权日:2021-05-20
标题:Map4k4 inhibitors and methods of synthesis and use thereof
发明人：AWASTHI VIBHUDUTTA; EEDA VENKATESWARARAO
权利人:UNIV OKLAHOMA
摘要:The compound DMX-5804, IUPAC name 5-(4-(2-methoxyethoxy)phenyl)-7-phenyl-3,4a,7,7a-tetrahydro-4H-pyrrolo[2,3-d]pyrimidin-4-one, is a potent and selective inhibitor of mitogen-activated protein kinase kinase kinase kinase-4 (MAP4K4). The present disclosure describes a scalable and practical synthesis process for making DMX-5804. The process (1) doesn't rely on transition metals, (2) has reduced duration of reactions, (3) is streamlined with significantly improved yields using low cost raw materials, (4) includes no microwave-assisted reactions, (5) does not require column purification, and (6) generally results in crystalized products having over a 95% purity in each step. The present disclosure also describes DMX-5804 analogs and derivatives for use in inhibiting MAP4K4, and scalable and practical processes for making such DMX-5804 analogs.

专利号:EP-1493431-B1
优先权日:2003-07-03
标题:Use of an extract of bauhinia for the preparation of pharmaceutical and cosmetic compositions
发明人：WIRTH CORINNA DR; BUCHHOLZ HERWIG DR
权利人:MERCK PATENT GMBH
摘要:Use of an aqueous or aqueous-alcoholic extract (A) of Bauhinia is claimed to make a composition for cosmetic or pharmaceutical treatment of skin and hair. Use of an aqueous or aqueous-alcoholic extract (A) of Bauhinia is claimed to make a composition for: (a) care, preservation or improvement of the general condition of the skin or hair; (b) prevention and/or inhibition of the aging process for human skin or hair; (c) for promoting healing of wounds; (d) for prevention and/or treatment of skin diseases associated with abnormal keratinization, and (e) for prevention and/or treatment of all malignant or benign growths of the dermis or epidermis. An independent claim is also included for a composition containing (A). ACTIVITY : Dermatological; Vulnerary; Antiseborrheic; Antipsoriatic; Cytostatic; Antiinflammatory; Virucide. MECHANISM OF ACTION : Protein glycosylation inhibitor. In a test, human fibroblasts were cultured in the presence of Vitamin C to stimulate collagen synthesis, then lysed and labeled with tritiated glucose for 15 days, Proteins were removed, extraction and precipitation were carried and the amount of bound glucose measured by liquid scintillation counting. Addition of an aqueous-alcoholic extract of Bauhinia fortificata (0.03 mg/ml), reduced protein glycosylation to 55% of that in a control.

专利号:JP-4242925-B2
优先权日:1992-10-05
标题 :Synthesis of D-chiro-3-inosose and â–² (+) â–¼ -D-chiro-inositol

专利号:WO-9112257-A2
优先权日:1990-02-16
标题 :Synthesis of sugars and amino acids from substituted and unsubstituted arene diols

专利号:WO-9116290-A1
优先权日:1990-04-16
标 题:Synthesis of cyclitols from substituted arene diols