CAS: 10563-23-2; N1-Ethylpropane-1,3-Diamine

相似化合物

13910-48-0 10239-34-6 273409-54-4

上下游产品

3-ethylamino propionitrile N-(3-benzylaminopropyl)-N'-(3-ethylaminopropyl)butane-1,4-diamine 1,N12-diethylspermineN1,N12-diethylspermine1-(3-Ethylamino-propylamino)-5,6,11-trimethyl-6H-pyrido[4,3-b]carbazol-9-ol N-ethyl-N'-(9-methoxy-5,11-dimethyl-6H-pyrido[4,3-b]carbazol-1-yl)-propane-1,3-diamine N,N'-bis(mesitylenesulfonyl)-N-ethyl-1,3-diaminopropane cyclopentyl-hydroxy-phenyl-acetic acid-(1-ethyl-1,4,5,6-tetrahydro-pyrimidin-2-ylmethyl ester); hydr°Chloride

3-乙胺基丙腈置于镍 氢气体系中,用 乙醇,氨 用作溶剂,化学反应生成N-乙基-1,3-丙二胺
参考文献:Thuillier,G. Et Al.,Bulletin De La Societe Chimique De France,1963,P. 1087-1090
标题:Thuillier,G. Et Al.,Bulletin De La Societe Chimique De France,1963,P. 1087-1090

专利信息

专利号:US-9738647-B2
优先权日:2009-12-24
标题:Methods for the synthesis of polycyclic guanidine compounds
发明人：GRIDNEV ALEXEI
权利人:NOVOMER INC; SAUDI ARAMCO TECH CO
摘要:The present invention provides methods for the synthesis of polycyclic guanidine compounds. In certain embodiments, provided methods include the step of contacting a described reagent with a triamine compound to provide a polycyclic guanidine compound.

专利号:US-7834174-B2
优先权日:2004-09-10
标 题 :Per-6-guanidino-, alkylamino-cyclodextrins, methods of their synthesis and their use for the compaction of DNA and intercellular delivery
发明人：MAVRIDIS IRENE M; YANNAKOPOULOU KONSTANTINA; ELIADOU KYRIAKI; MOURTZIS NIKOLAOS; AGGELIDOU CHRYSI
权利人:MAVRIDIS IRENE M; YANNAKOPOULOU KONSTANTINA; ELIADOU KYRIAKI; MOURTZIS NIKOLAOS; AGGELIDOU CHRYSI
摘要:The invention relates to new compounds of type hexakis(6-deoxy-6-NH(CH 2 ) n —R 1 )α-cyclodextrin and heptakis(6-deoxy-6-NH(CH 2 ) n —R 1 )-(β-cyclodextrin, and octakis(6-deoxy-6-NH(CH 2 ) n —R 1 )-γ-cyclodextrin, where n=2-6 when R 1 =NH 2 and n=0 when R 1 =C(â•?NH)NH 2 and n=2-6 when R 1 =NH—C(â•?NH)NH 2 and their use in the compaction of DNA and in cell permeation. The invention also relates to methods of synthesis of the above compounds.

专利号:EP-1567195-B1
优先权日:2002-11-26
标题 :Dendrimer conjugates for selective solubilisation of protein aggregates
发明人：HEEGAARD PETER; BOAS ULRIK
权利人:UPFRONT CHROMATOGRAPHY AS
摘要:Dendrimer conjugates are presented, which are formed between a dendrimer and a protein solubilising substance. Such dendrimer conjugates ar effective in the treatment of protein aggregate-related diseases (e.g. prion-related diseases). The protein solubilising substance and the dendrimer together show a protein aggregate solubilising effect higher than a physical mixture of the dendrimer and the protein solubilising substance (i.e. a synergistic effect). Such dendrimer conjugates are useful in the treatment or prevention of protein aggregate-relates diseases, in disinfection/decontamination processes and in classifying or identifying protein aggregates. The synthesis of such dendrimer conjugates from readily-available starting materials is described.

专利号:US-2009111737-A1
优先权日:1999-05-24
标题:Novel antibacterial agents
发明人：CHRISTENSEN BURTON G; MORAN EDMUND J; GRIFFIN JOHN H; JUDICE J KEVIN; MU YONGQI; PACE JOHN L; MAMMEN MATHAI; AGGEN JAMES
权利人:CHRISTENSEN BURTON G; MORAN EDMUND J; GRIFFIN JOHN H; JUDICE J KEVIN; MU YONGQI; PACE JOHN L; MAMMEN MATHAI; AGGEN JAMES
摘要:This invention relates to novel multibinding compounds (agents) that are antibacterial agents. The multibinding compounds of the invention comprise from 2-10 ligands covalently connected by a linker or linkers, wherein each of said ligands in their monovalent (i.e., unlinked) state have the ability to bind to a an enzyme involved in cell wall biosynthesis and metabolism, a precursor used in the synthesis of the bacterial cell wall and/or the bacterial cell surface thereby interfere with the synthesis and/or metabolism of the cell wall. In particular the multibinding compounds of the invention comprise from 2-10 ligands covalently connected by a linker or linkers, wherein each of said ligands hasn a ligand domain capable of binding to penicillin binding proteins, a transpeptidase enzyme, a substrate of a transpeptidase enzyme, a beta-lactamase enzyme, pencillinase enzyme, cephalosporinase enzyme, a transglycoslase enzyme, or a transglycosylase enzyme substrate; Preferably, the ligands are selected from the beta lactam or glycopeptide class of antibacterial agents.

专利号:WO-2019013789-A1
优先权日:2017-07-12
标 题 :ANTIMICROBIAL COMPOUNDS
发明人：REDDY HARIPRASADA R KANNA; SEBAHAR PAUL R; SERRANO CATHERINE M; LOOPER RYAN E
权利人:CURZA GLOBAL LLC; THE UNIV OF UTAH RESEARCH FOUNDATION
摘要:The invention relates to compounds of formula I or their pharmaceutically acceptable salts. The compounds of formula I are antimicrobial agents which inhibit, for example, Mycobacterium tuberculosis (Mtb) H37Ra. The compounds of formula I also have anti-tuberculous activity, exhibit limited cytotoxicity and inhibit protein synthesis. The invention also relates to methods of making compounds of formula I, as well as methods of using compounds of formula I for the treatment of bacterial infections, particularly tuberculosis.

专利号:WO-2019013790-A1
优先权日:2017-07-12
标题:ANTIMICROBIAL COMPOUNDS AND USES THEREOF
发明人：REDDY HARIPRASADA; SEBAHAR PAUL; LOOPER RYAN
权利人:CURZA GLOBAL LLC; THE UNIV OF UTAH RESEARCH FOUNDATION
摘要:The invention relates to compounds of formula I: or pharmaceutically acceptable salts thereof. The compounds of formula I are antimicrobial agents which inhibit, for example, Mycobacterium tuberculosis (Mtb) H37Ra. The compounds of formula I also have anti-tuberculous activity, exhibiting limited cytotoxicity, and inhibiting protein synthesis. The invention also relates to methods of making compounds of Formula I, as well as methods of using the compounds of Formula I for the treatment of bacterial infections, particularly tuberculosis.