CAS: 42711-75-1; 3-Hydroxyadamantane-1-Carboxylic Acid

上下游产品

CAS号828-51-3 1-金刚烷甲酸 | CAS号68435-07-4 3-羟基-1-金刚烷羧酸甲酯 | CAS号21816-08-0 3-溴-1-金刚烷甲酸 | CAS号106094-47-7 (3-氟金刚烷-1-基)甲醇 | CAS号34859-74-0 3-氯金刚烷-1-羧酸 | CAS号38584-37-1 3-羟基-1-金刚烷甲醇 | CAS号39917-38-9 1-(3-羟基金刚烷-1-基)乙酮 | CAS号90812-24-1 3-(1-氨基乙基)-1-金刚烷醇盐酸盐 | CAS号21816-08-0 3-溴-1-金刚烷甲酸 | CAS号68435-07-4 3-羟基-1-金刚烷羧酸甲酯 | CAS号880-50-2 1-Fluoro-3-adam... | CAS号42711-77-3 3-碘金刚烷-1-羧酸

1-金刚烷甲酸置于氢氧化钾,Potassium Permanganate体系中,用 水 作为反应溶剂,以54%的收率获得产物3-羟基金刚烷-1-羧酸
参考文献:使用distonic自由基阴离子方法研究1-金刚烷基的气相反应性.
标题:使用distonic自由基阴离子方法研究1-金刚烷基的气相反应性.
摘要:使用改进的电喷雾电离线性离子阱质谱仪,用一系列中性试剂观察了桥头3-羧基--1-金刚烷基自由基阴离子的气相反应.观测到该二元自由基阴离子经历暗示自由基反应性的过程,包括自由基-自由基结合反应,取代反应和碳-碳双键的加成.测量了3-羧基1-金刚烷基自由基阴离子与以下试剂的反应速率常数(单位为10(-12)cm(3)分子(-1)s(-1)):(18)o (2)(85 +/-4),No(38.4 +/-0.4),I(2)(50 +/-50),Br(2)(8 +/-2),Ch(3)ssch(3)(12 +/-2),苯乙烯(1.20 +/-0.03),Chcl(3)(h抽象0.41 +/-0.06,Cl抽象0.65 +/-0.1),Cdcl(3)(d抽象0.035 + /-0.01,Cl抽象度0.723 +/-0.005),烯丙基溴(br提取0.53 +/-0.04,烯丙基化0
DOI:10.1039/b711156H

专利信息

专利号:US-9255079-B2
优先权日:2009-12-10
标 题 :Photoacid generators and photoresists comprising same
发明人：LI MINGQI; AQAD EMAD; LIU CONG; MATTIA JOSEPH; XU CHENG-BAI; BARCLAY GEORGE G
权利人:LI MINGQI; AQAD EMAD; LIU CONG; MATTIA JOSEPH; XU CHENG-BAI; BARCLAY GEORGE G; ROHM & HAAS ELECT MAT
摘要:New methods are provided for synthesis of photoacid generator compounds (“PAGsâ€?), new photoacid generator compounds and photoresist compositions that comprise such PAG compounds. In a particular aspect, sulfonium-containing (S+) photoacid generators and methods of synthesis of sulfonium photoacid generators are provided.

专利号:US-7250529-B2
优先权日:2004-09-17
标题:Synthesis process for 2-(3-hydroxy-1-adamantyl)-2-oxoacetic acid
发明人：WILLIAMS ERIC L
权利人:ALBEMARLE CORP
摘要:A highly advantageous process for the preparation of 2-(3-hydroxy-1-adamantyl)-2-oxoacetic acid or a salt thereof is described. The process comprises subjecting 1-acetyl 3-hydroxyadamantane to liquid phase oxidation with permanganate to produce 2-(3-hydroxy-1-adamantyl)-2-oxoacetic acid or a salt thereof, with acidification to form the free acid when appropriate.

专利号:US-8043786-B2
优先权日:2003-03-05
标题 :Acid generators, sulfonic acids, sulfonyl halides, and radiation sensitive resin compositions
发明人：EBATA SATOSHI; WANG YONG; NISHIMURA ISAO
权利人:JSR CORP
摘要:The invention provides novel acid generators which are unproblematic in combustibility and accumulation inside the human body and can generate acids having high acidities and high boiling points and exhibiting properly short diffusion lengths in resist coating films and which permit the formation of resist patterns excellent smoothness with little dependence on the denseness of a mask pattern; sulfonic acids generated from the acid generators; sulfonyl halides useful as raw material in the synthesis of the acid generators; and radiation-sensitive resin compositions containing the acid generators. The acid generators have structures represented by the general formula (I), n nwherein R 1 is a monovalent substituent such as alkoxycarbonyl, alkylsulfonyl, or alkoxysulfonyl; R 2 to R 4 are each hydrogen or alkyl; k is an integer of 0 or above; and n is an integer of 0 to 5. Among the radiation-sensitive resin compositions, a positive one contains a resin having acid-dissociable groups in addition to the above acid generator, while a negative one contains an alkali-soluble resin and a crosslinking agent in addition to the acid generator.

专利号:RU-2178400-C2
优先权日:2000-03-17
标题:Method of synthesis of 1- and 2-chloroadamantane from 1- and 2-adamantanol

专利号:WO-2011012322-A2
优先权日:2009-07-31
标 题:Synthesis and use of vildagliptin for the preparation of pharmaceutical dosage forms

专利号:US-5596020-A
优先权日:1993-06-25
标题:Amino bi- and tri-carbocyclic alkane bis-aryl squalene synthase inhibitors
发明人：MORRIS ROBERT L; NEUENSCHWANDER KENT W; LEARN KEITH S; SCOTESE ANTHONY C
权利人:RHONE POULENC RORER PHARMA
摘要:This invention relates to a class of novel amino bi- and tri-carbocyclic alkane compounds having bis-aryl substitution which exhibit squalene synthase inhibition properties. The bi- and tri-carbocyclic alkane ring contains an amino group and the ring is further linked or bridged to two mono- and/or bicyclic rings. Compounds of this invention reduce levels of serum cholesterol in the body without significantly reducing mevalonic metabolite synthesis. This invention relates also to pharmacological compositions and method of treatment for lowering serum cholesterol levels using the compounds of this invention.