CAS: 593-55-5; Ethylamine Hydrobromide

上下游产品

CAS号29636-75-7 3-bromopropiophenone | CAS号75-04-7 乙胺 | CAS号79-27-6 四溴乙烷 | CAS号60-29-7 乙醚 | CAS号16486-84-3 ENANTHALDEHYDE,... | CAS号115197-42-7 ethyl-carboximi... | CAS号7732-18-5 水 | CAS号75-15-0 二硫化碳 | CAS号64-17-5 乙醇

2-Bromoheptanal,乙胺 反应生成 乙胺氢溴酸盐
参考文献:Kirrmann,Annales De Chimie (Cachan,France),1929,Vol. <10>11,P. 232,271
标题:Kirrmann,Annales De Chimie (Cachan,France),1929,Vol. <10>11,P. 232,271

专利信息

专利号:US-6147226-A
优先权日:1999-02-16
标题 :Synthesis of cyclopentyl 2-thienyl ketone, tiletamine and tiletamine acid addition salts, such as tiletamine hydrochloride
发明人：LAPIN YURI ALEKSANDROVICH; SANCHEZ IGNACIO H
权利人:GREAT LAKES CHEMICAL CORP
摘要:A water-scavenging solvent, such a polyphosphoric acid, can be used for the synthesis of cyclopentyl 2-thienyl ketone by the direct acylation of cyclopentanecarboxylic acid without first reacting the cyclopentanecarboxylic acid with thionylchloride to form the acid chloride, while achieving new and unexpected yields. A tiletamine-free base can be made from the cyclopentyl 2-thienyl ketone with a halide in the presence of a solvent for the cyclopentyl 2-thienyl ketone to form a halogenated cyclopentane 2-thienyl ketone, aminating the halogenated cyclopentane 2-thienyl ketone by reaction with an amine, and subjecting the reaction product to thermal rearrangement, in a suitable solvent, and at a sufficient temperature to form tiletamine free base. Each step for the formation of tiletamine free base can be accomplished using the same solvent, e.g., dichlorobenzene so that intermediates need not be isolated between reactions.

专利号:US-5969159-A
优先权日:1999-02-16
标 题 :Synthesis of cyclopentyl 2-thienyl ketone tiletamine and tiletamine acid addition salts such as tiletamine hydrochloride
发明人：LAPIN YURI ALEKSANDROVICH; SANCHEZ IGNACIO H
权利人:GREAT LAKES CHEMICAL CORP
摘要:Solid, non-tin-containing catalysts can be used for the synthesis of cyclopentyl 2-thienyl ketone by the reaction of cyclopentanecarboxylic acid chloride and thiophene, while achieving new and unexpected yields. Aluminum trichloride is both cheaper than stannic chloride and it is easier to deal with as a waste stream. The successful use of graphite as a catalyst for the reaction of cyclopentanecarboxylic acid chloride and thiophene provides a mild and ecologically friendly method for carrying out the Friedel-Crafts reaction. A tiletamine-free base can be made from the cyclopentyl 2-thienyl ketone with a halide in the presence of a solvent for the cyclopentyl 2-thienyl ketone to form a halogenated cyclopentane 2-thienyl ketone; aminating the halogenated cyclopentane 2-thienyl ketone by reaction with an amine; and subjecting the reaction product to thermal rearrangement, in a suitable solvent, and at a sufficient temperature to form tiletamine free base. Each step for the formation of tiletamine free base can be accomplished using the same solvent, e.g., dichlorobenzene so that intermediates need not be isolated between reactions.

专利号:US-2018208543-A1
优先权日:2017-01-26
标 题 :New method for synthesis of fenfluramine, and new compositions comprising it
发明人：PALOMBI GIOVANNI; ZAGAMI MICHAEL
权利人:FRAU PHARMA S R L
摘要:A new process for preparing the fenfluramine molecule and new compositions containing fenfluramine obtainable with the claimed process.

专利号:EP-3170807-A1
优先权日:2015-11-23
标题:New method for synthesis of fenfluramine, of isomers therof and/or of analogs thereof, and new compositions comprising it

专利号:CN-101353170-B
优先权日:2007-07-26
标 题:Method for synthesis of beta-zeolite

专利号:US-5698425-A
优先权日:1990-08-20
标 题:Method of protecting plants by transformation with genes for the synthesis of antipathogenic substances