CAS: 619-08-9; 2-Chloro-4-Nitrophenol

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CAS号95-57-8 邻氯苯酚 | CAS号100-02-7 对硝基苯酚 | CAS号121-73-3 间氯硝基苯 | CAS号99-54-7 1,2-二氯-4-硝基苯 | CAS号3209-22-1 2,3-二氯硝基苯 | CAS号104-91-6 对亚硝基酚 | CAS号20294-55-7 2-Bromo-6-chlor... | CAS号3964-56-5 4-溴-2-氯苯酚 | CAS号58286-59-2 methyl 2-chloro... | CAS号524955-09-7 [3-氯-4-(吡啶-2-甲氧... | CAS号35023-71-3 2-氯-4-硝基苯基-2,3,... | CAS号4920-79-0 2-氯-4-硝基苯甲醚 | CAS号443882-99-3 3-氯-4-(3-氟苄氧基)硝基苯 | CAS号50508-54-8 4-苄氧基-3-氯硝基苯 | CAS号3964-54-3 N-(3-氯-4-羟基苯基)乙酰胺 | CAS号946-31-6 6-氯-2,4-二硝基苯酚 | CAS号3964-52-1 2-氯-4-氨基苯酚 | CAS号21278-58-0 Benzene,2-chlor... | CAS号22197-84-8 Benzonitrile,4-...

对硝基苯酚置于n-Chloro-N-(Benzenesulfonyl)Benzenesulfonamide体系中,用 乙腈 作为反应溶剂,化学反应 0.5H,以99.6%的收率获得产物2-氯-4-硝基苯酚
参考文献:N-氯-N-(苯磺酰基)苯磺酰胺(ncbsi)对活化的芳烃进行无活化剂的快速,环保的氯化反应
标题:N-氯-N-(苯磺酰基)苯磺酰胺(ncbsi)对活化的芳烃进行无活化剂的快速,环保的氯化反应
摘要:N-氯-N-(苯磺酰基)苯磺酰胺(ncbsi)首次被开发为无需任何活化剂即可直接氯化各种活化的芳烃和杂环的氯化试剂.的比较中,计算机芯片上进行研究,以确定ncbsi亲电性质和市售ñ氯试剂,以揭示理论的角度来看的反应性.通过避免使用有害的次氯酸叔丁基酯的改进方法制备了该试剂.与其他n-氯试剂相比,该试剂具有很高的反应活性.试剂n的前体从废废水中回收-(苯磺酰基)苯磺酰胺,可将其再循环以合成ncbsi.环保协议同样适用于工业上重要的氯氧亚麻酚作为抗菌剂的合成.
DOI:10.1016/j.Tetlet.2020.152689

专利信息

专利号:US-2014228554-A1
优先权日:2011-03-18
标 题:Synthesis of new fucose-containing carbohydrate derivatives
发明人：CHAMPION ELISE; DEKANY GYULA; HEDEROS MARKUS; AGOSTON KAROLY
权利人:GLYCOM AS; GLYCOM AS
摘要:A method for the synthesis of a fucooligosaccharide glycosides by reacting a fucosyl donor with H-A-R 1 or a salt thereof, wherein A and R 1 are as defined herein, under the catalysis of an enzyme capable of transferring fucose is provided. The fucooligosaccharid glycoside compounds, or derivatives thereof, their use in the manufacture of human milk oligosaccharides, and a method of manufacture of human milk oligosaccharides, are also provided.

专利号:US-2017218006-A1
优先权日:2014-07-31
标题 :Synthesis of Phosphoramidates
发明人：WILHELM THORSTEN; SPITZENSTÄTTER HANS-PETER; SCHÖNE OLGA; RICHTER FRANK; SCHREINER ERWIN
权利人:SANDOZ AG
摘要:A process for the preparation of a compound of formula (I) including all isomers, stereoisomers, enantiomers and diastereomers thereof (I), and salts thereof; the process comprising providing a mixture comprising a compound of formula (II) and a compound of formula (III) subjecting the mixture provided in a) to reaction conditions in the presence of one or more Lewis acids to the mixture provided in a), obtaining a mixture comprising the compound of formula (I).

专利号:US-2013004979-A1
优先权日:2010-06-11
标 题 :Glycosyltransferase reversibility for sugar nucleotide synthesis and microscale scanning
发明人：THORSON JON S; GANTT RICHARD W; PELTIER-PAIN PAULINE MARIE JEANNE
权利人:WISCONSIN ALUMNI RES FOUND; THORSON JON S; GANTT RICHARD W; PELTIER-PAIN PAULINE MARIE JEANNE
摘要:The present invention generally relates to materials and methods for exploiting glycosyltransferase reversibility for nucleotide diphosphate (NDP) sugar synthesis. The present invention provides engineered glycosyltransferase enzymes characterized by improved reaction reversibility and expanded sugar donor specificity as compared to corresponding non-mutated glycosyltransferase enzymes. Such reagents provide advantageous routes to NDP sugars for subsequent use in a variety of biomedical applications, including enzymatic and chemo-enzymatic glycorandomization.

专利号:US-8637287-B2
优先权日:2010-06-11
标题:Glycosyltransferase reversibility for sugar nucleotide synthesis
发明人：THORSON JON S; GANTT RICHARD W
权利人:THORSON JON S; GANTT RICHARD W; WISCONSIN ALUMNI RES FOUND
摘要:The present invention generally relates to materials and methods for exploiting glycosyltransferase reversibility for nucleotide diphosphate (NDP) sugar synthesis. The present invention provides engineered glycosyltransferase enzymes characterized by improved reaction reversibility and expanded sugar donor specificity as compared to corresponding non-mutated glycosyltransferase enzymes. Such reagents provide advantageous routes to NDP sugars for subsequent use in a variety of biomedical applications, including enzymatic and chemoenzymatic glycorandomization.

专利号:EP-3174892-A1
优先权日:2014-07-31
标 题:Synthesis of phosphoramidates

专利号:US-2011245484-A1
优先权日:2010-03-31
标 题 :Stereoselective synthesis of phosphorus containing actives