CAS: 1140-17-6; (2-Aminophenyl)(4-Bromophenyl)Methanone

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上下游产品

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2-(Toluene-4-Sulfonylamino)-Benzoyl Chloride置于三氯化铝,硫酸体系中,化学反应 4.25H,反应生成2-氨基-4'-溴二苯甲酮
参考文献:Synthesis And Biological Evaluation Of Substituted 2-Sulfonyl-Phenyl-3-Phenyl-Indoles: A New Series Of Selective Cox-2 Inhibitors
标题:Synthesis And Biological Evaluation Of Substituted 2-Sulfonyl-Phenyl-3-Phenyl-Indoles: A New Series Of Selective Cox-2 Inhibitors
摘要:A New Series Of Substituted 2-Sulfonyphenyl-3-Phenyl-Indole Derivatives Were Synthesized And Evaluated For Their Ability To Inhibit Cox-2 And Cox-Lenzymes. Most Of The Compounds Synthesized Were Found To Be Highly Potent And Selective Inhibitors Of Cox-2. This Work Led To The Discovery Of 2-Aminosulfonylphenyl-3-Phenyl-Indole 5A Which Possesses Higher Activity And Selectivity For Cox-2 Than Celecoxib Both In Vitro And In Vivo. (C) 2003 Elsevier Science Ltd. All Rights Reserved.
Doi:10.1016/s0968-0896(03)00046-4

专利信息

专利号:US-4118384-A
优先权日:1976-02-21
标题 :Process for preparation of azo dyestuffs by coupling in presence of aromatic sulphonic acid-formaldehyde reaction product
发明人：MOLLS HANS-HEINZ; SCHIWY WILLY; HORNLE REINHOLD; NEBELING REINHARD
权利人:BAYER AG
摘要:Dyestuff dispersions and dyestuff solutions free from salt or at least having a low salt content are obtained in that the diazotization is carried out with addition of free dispersing agent acid to which, after the synthesis, either no basic agents are added or basic agents are added only up to a pH value of 3. The disclosed process gives dyestuff compositions of low salt content and results in readily dispersible dyestuffs when water insoluble dyestuffs are prepared and stable solutions when water soluble dyestuffs are prepared. The process is widely applicable and chemical constitution of the dyestuffs is conventional.

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优先权日:2018-12-03
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优先权日:2024-04-24
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优先权日:2019-09-30
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