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CAS号121-43-7 硼酸三甲酯 | CAS号138526-69-9 5-溴-1,2,3-三氟苯 | CAS号223440-94-6 2,4,6-三(3,4,5-三... | CAS号7732-18-5 水 | CAS号223440-94-6 2,4,6-三(3,4,5-三... | CAS号1489-53-8 1,2,3-三氟苯 | CAS号898777-56-5 3-(3,4,5-TRIFLU... | CAS号915416-45-4 3',4',5'-三氟联苯基-2-胺合成工艺路线路线简述
- 合成目标产物 3,4,5-Trifluorophenylboronic Acid 主要起始原料 Hydrochloric Acid And 2-Methoxy-5,5-Dimethyl-1,3,2-Dioxaborinane And 5-Bromo-1,2,3-Trifluorobenzene
- (文献来源)合成步骤主要原料 Hydrochloric Acid 和 2-Methoxy-5,5-Dimethyl-1,3,2-Dioxaborinane 和 5-Bromo-1,2,3-Trifluorobenzene
3,4,5-三氟溴苯置于magnesium,硼酸三甲酯,盐酸体系中,用 水 用作溶剂,化学反应生成3,4,5-三氟苯硼酸
参考文献:Compound Having Tetrahydronaphthalene Skeleton And Liquid Crystal Composition Containing The Same
标题:Compound Having Tetrahydronaphthalene Skeleton And Liquid Crystal Composition Containing The Same
专利信息
专利号:US-12428425-B2
优先权日:2020-05-04
标 题:Heterocyclic compounds as triggering receptor expressed on myeloid cells 2 agonists and methods of use
发明人:CZABANIUK LARA C; HOPPER TIMOTHY; HOUZE JONATHAN B; PANTELEEV JANE; RESCOURIO GWENAELLA; SANTORA VINCENT; WANG HAOXUAN; WHITE RYAN D; WONG ALICE R; WU YONGWEI; BOS MAXENCE; MANCUSO JOHN; FRANZONI IVAN
权利人:AMGEN INC; VIGIL NEUROSCIENCE INC
摘要:The present disclosure provides compounds of Formula I, useful for the activation of Triggering Receptor Expressed on Myeloid Cells 2 (“TREM2â€?).This disclosure also provides pharmaceutical compositions comprising the compounds, uses of the compounds, and compositions for treatment of, for example, a neurodegenerative disorder. Further, the disclosure provides intermediates useful in the synthesis of compounds of Formula I.
专利号:US-2011250454-A1
优先权日:2010-04-09
标 题:Preparation of nebivolol
发明人:HALDAR PRANAB; GOLLA CHINA MALAKONDAIAH; SWAPNA AKULA; KUMAR KARRI VIJAYA; JAWLEKAR SUHAS; TUMMALA ARJUN KUMAR; PATRO DEEPALI; YARRAGUNTLA SESHA REDDY; RAMAKRISHNAN SRIVIDYA; CHIMALA VENKATA RAMANA REDDY
权利人:HALDAR PRANAB; GOLLA CHINA MALAKONDAIAH; SWAPNA AKULA; KUMAR KARRI VIJAYA; JAWLEKAR SUHAS; TUMMALA ARJUN KUMAR; PATRO DEEPALI; YARRAGUNTLA SESHA REDDY; RAMAKRISHNAN SRIVIDYA; CHIMALA VENKATA RAMANA REDDY
摘要:Processes for the synthesis of pharmacologically active 2,2-iminobisethanol derivatives, e.g., 2H-1-benzopyran-2 methanol-α,α′-iminobis(methylene)]bis-[6-fluoro-3,4-dihydro-[2R*[R*[R*(S*)]]]], and their pharmaceutically acceptable salts.
专利号:US-9284336-B1
优先权日:2014-08-21
标题 :Synthesis of 4-(pentafluorosulfanyl)benzenediazonium tetrafluoroborate and analogs
发明人:LAALI KENNETH K
权利人:LAALI KENNETH K; UNIV NORTH FLORIDA
摘要:4-(pentafluorosulfanyl)benzenediazonium tetrafluoroborate salt was synthesized and isolated. The pentafluorosulfanyl salt was examined in a wide assortment of reactions to form novel SF 5 -bearing alkenes, alkynes, and biaryl derivatives using Heck-Matsuda, Sonogashira, and Suzuki coupling protocols. Dediazoniation of the salt furnished the corresponding p-SF 5 —C 6 H 4 X, C 6 H 4 OS(O)(CF 3 )â•?NSO 2 CF 3 , and p-SF 5 —C 6 H 4 —NTf 2 derivatives. The azide derivative p-SF 5 —C 6 H 4 N 3 entered into click chemistry with phenylacetylenes to furnish the corresponding triazoles. Various SF 5 -bearing alkenes were synthesized by coupling reactions using a metal catalyst. Fluorodediazoniation selectively furnished the fluoro derivative p-SF 5 —C 6 H 4 F. Homolytic dediazoniation gave the unsymmetrical biaryls, thus demonstrating the broad utility of pentafluorosulfanyl diazonium salts as building blocks of SF5-aromatics that are in high demand in many branches of chemistry including biomedicine and materials chemistry.
专利号:EP-4378929-A1
优先权日:2022-11-29
标题 :Synthesis of aromatic boronic acids
发明人:KISIN-FINFER EINAT; FALLEK REUT
权利人:ADAMA MAKHTESHIM LTD
摘要:The invention relates to a method for the preparation of phenylboronic acids of formula (I), or combinations thereof, key intermediates in the preparation of compounds of interest in the agrochemical industry. The process comprises adding a borate over a Grignard reagent.
专利号:WO-2024159724-A1
优先权日:2023-02-03
标 题:O-biphenyl oxazoline compound and synthesis method therefor
发明人:ZHU JIANSHE; WANG MINGCHUN; LI QINGYI
权利人:KEYLAB JIANGSU TECH CO LTD
摘要:A synthesis method for an o-biphenyl oxazoline compound. An aryl metal compound as represent by formula II reacts with aryl oxazoline as represented by formula III to generate the o-biphenyl oxazoline compound as represented by formula I. The o-biphenyl oxazoline compound can be used for industrial preparation of o-aminobiphenyl compounds, and used for synthesizing succinate dehydrogenase inhibitor fungicides (IV) such as fluxapyroxad, bixafen, boscalid, and pyraziflumid.
专利号:UA-122133-C2
优先权日:2014-11-19
标题 :METHOD OF SYNTHESIS OF BENZAZEPINE DERIVATIVES