CAS: 3290-99-1; 4-Methoxybenzohydrazide

该化合物是一种水合二氮衍生物,其特征是附于苯并合二氮核心结构的甲氧基组,该化合物主要用作有机合成的多种中间体,特别是在制备药品,农用化学品和乙型环化合物方面,其反应性氢化二苯并呋喃功能组可产生高效的凝结反应,使其对合成氢氮和其他含氮的脚架具有价值.甲基氧基次组分体可增强有机溶剂的溶性,并可影响电子特性,有助于选择性化学转化.该化合物通常作为高纯度固体供应,确保研究和工业应用的一贯性能.建议妥善处理和储存,因为其对水分和氧化的敏感性.

结构式图片

欧盟法规

ECHA物质C&L通报REACH预注册

上下游产品

CAS号121-98-2 茴香酸甲酯 | CAS号94-30-4 4-甲氧基苯甲酸乙酯 | CAS号100-09-4 对甲氧基苯甲酸 | CAS号95-54-5 邻苯二胺(OPD) | CAS号100-07-2 对甲氧基苯甲酰氯 | CAS号123-11-5 4-甲氧基苯甲醛; 对甲氧基苯... | CAS号99-96-7 4-羟基苯甲酸 | CAS号121-98-2 茴香酸甲酯 | CAS号100-09-4 对甲氧基苯甲酸 | CAS号141078-92-4 3-(4-methoxyphe... | CAS号95167-41-2 DY131 | CAS号51220-57-6 ETHYL 2-[(4-MET... | CAS号94-30-4 4-甲氧基苯甲酸乙酯 | CAS号302910-62-9 N-(cyclohexylid... | CAS号25877-46-7 4-(5-甲基-1,3,4-噁... | CAS号829-35-6 2-(4-甲氧基苯基)-1,3... | CAS号3424-93-9 4-甲氧基苯甲酰胺

合成工艺路线路线简述

    1-(4-Methoxybenzoyl)-Imidazole置于一水合肼体系中,用 四氢呋喃 用作溶剂,化学反应生成对甲氧基苯甲酰肼
    参考文献:Sar Studies On 1,2,4-Triazolo[3,4-B][1,3,4]Thiadiazoles As Inhibitors Of Mtb Shikimate Dehydrogenase For The Development Of Novel Antitubercular Agents
    标题:Sar Studies On 1,2,4-Triazolo[3,4-B][1,3,4]Thiadiazoles As Inhibitors Of Mtb Shikimate Dehydrogenase For The Development Of Novel Antitubercular Agents
    摘要:三唑噻二唑是一种具有较强抗结核活性的药物,对mtsd有适度的抑制作用,并且没有明显的细胞毒性.
    Doi:10.1039/c5Ra19334F

    海关参考信息

    专利信息


    专利号:US-2021323987-A1
    优先权日:2018-08-20
    标题:Methods for the Synthesis of Heteroatom Containing Polycyclic Aromatic Hydrocarbons
    发明人:GARG NEIL K; DARZI EVAN R; BARBER JOYANN S; SUSICK ROBERT; CHARI JASON; SPENCE KATIE
    权利人:UNIV CALIFORNIA
    摘要:Methods for the synthesis of polycyclic aromatic hydrocarbons and synthesis platforms for performing such syntheses are provided. Methods and platforms are provided that allow for the synthesis of aza-polycyclic aromatic hydrocarbons by an expedient ring assembly. Methods and platforms allow for a modular approach to synthesis that provide multiple new C—C bonds in sequential pericyclic reactions, thus giving access to compounds with multiple axes of substitution.

    专利号:US-9085550-B2
    优先权日:2005-01-21
    标题 :Ligands for estrogen related receptors and methods for synthesis of said ligands
    发明人:FORMAN BARRY; YU DONNA
    权利人:FORMAN BARRY; YU DONNA; HOPE CITY
    摘要:Estrogen-Related Receptor (ERR) modulating compounds and methods for synthesis of said compounds are described.

    专利号:US-2006189825-A1
    优先权日:2005-01-21
    标题:Ligands for estrogen related receptors and methods for synthesis of said ligands

    专利号:WO-2014051445-A1
    优先权日:2012-09-26
    标 题:Pyrrole-3,4-dicarboxamides
    发明人:PACIOREK PATRYCJA; SZKLARZEWICZ JANUSZ
    权利人:UNIV JAGIELLOŃSKI
    摘要:The invention relates to the pyrrole derivatives with the general formula in which R 1 is alkyl group C 1 - C 10 , straight or branched, R 2 is -H, -C1, -OH, -NH 2 or -OCH 3 . The invention includes also the method of the synthesis of pyrrole derivatives in the reaction of ketoanilide with hydrazide, with the use of vanadium compound as a reaction promoter.

    专利号:US-6291504-B1
    优先权日:1999-10-20
    标题:Acylsemicarbazides and their uses
    发明人:NUGIEL DAVID A; CARINI DAVID J; DI MEO SUSAN V; VIDWANS ANUP P; YUE EDDY W
    权利人:DU PONT PHARM CO
    摘要:The present invention relates to the synthesis of a new lass of indeno[1,2-c]pyrazol-4-ones of formula (I):that are potent inhibitors of the class of enzymes known as cyclin dependent kinases, which relate to the catalytic subunits cdk1-9 and their regulatory subunits know as cyclins A-H.This invention also provides a novel method of treating cancer or other proliferative diseases by administering a therapeutically effective amount of one of these compounds or a pharmaceutically acceptable salt form thereof. Alternatively, one can treat cancer or other proliferative diseases by administering a therapeutically effective combination of one of the compounds of the present invention and one or more other known anti-cancer or anti-proliferative agents.

    专利号:US-2013131340-A1
    优先权日:2005-01-21
    标题 :Ligands for estrogen related receptors and methods for synthesis of said ligands
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    主要参考文献

    [参考文献]: Cheuk-Fai Chow, Et Al. Metallodynamers: Neutral Double-Dynamic Metallosupramolecular Polymers. Chem Asian J. 2008 Sep 1;3(8-9):1324-35.

    合成参考文献


    参考文献:10.1107/s1600536811014012
    摘要:Bi Y. 4-Meth-oxy-N'-(4-meth-oxy-benzyl-idene)benzohydrazide. Acta Crystallogr Sect E Struct Rep Online. 2011 May 01;67(Pt 5):o1182.
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