CAS: 352-11-4; 1-(Chloromethyl)-4-Fluorobenzene

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CAS号459-56-3 对氟苯甲醇 | CAS号352-32-9 对氟甲苯 | CAS号29180-23-2 p-fluorobenzyl ion | CAS号462-06-6 氟苯 | CAS号50-00-0 甲醛 | CAS号7647-01-0 盐酸 | CAS号56-23-5 四氯化碳 | CAS号5435-44-9 N-(1-ethoxycarb... | CAS号347-91-1 2-(4-氟苯基)苯乙酮 | CAS号587-79-1 4-氟二苯基甲烷 | CAS号457-68-1 双(4-氟苯基)甲烷 | CAS号3462-95-1 (4-氟苄基)三苯基氯化膦 | CAS号55096-88-3 N-苄基-4-氟苄基胺 | CAS号396-11-2 2-(4-氟苄氧基)-苯甲酸 | CAS号312693-07-5 4-氟苄基氯化锌 | CAS号56442-17-2 4-(4-氟苯甲氧基)苯甲醛 | CAS号456-19-9 4-氟苯亚甲基氯 | CAS号405-66-3 N-甲基-4-氟苄胺

对氟甲苯置于氯体系中,用 四氯化碳 作为反应溶剂,化学反应生成 4-氟氯苄
参考文献:取代的甲基:取代作用
标题:取代的甲基:取代作用
摘要:由f 19 NMR确定了一系列单取代,二取代和三取代的me基团ch 2 X,Chx 2和cx 3的取代基参数,其中x为f,Cl,Br,Ome,Scf 3和cn对相应的间-和对-氟甲苯进行测定.仅对于氰基取代基发现了取代的加成线性效应.消散后,对于x为f,Cl,Br和scf 3(尤其是氯和溴)的基团,观测到的饱和效应归因于这些取代基的未共享p电子与环的π系统的空间相互作用.
DOI:10.1016/s0040-4020(01)92493-7

专利信息

专利号:US-2008086013-A1
优先权日:2006-06-15
标 题:Carbometallation of alkynes and improved synthesis of uniquinones
发明人：LIPSHUTZ BRUCE H
权利人:UNIV CALIFORNIA
摘要:Methods for the carbometallation of alkynes are presented. Those are useful for the synthesis of CoQ 10 and other ubiquinones as well as for the synthesis of ubiquinol analogs.

专利号:US-2006167289-A1
优先权日:2003-12-05
标题 :Practical, cost-effective synthesis of ubiquinones
发明人：LIPSHUTZ BRUCE H; BERL VOLKER; SCHEIN KARIN; WETTERICH FRANK
权利人:ZYMES LLC
摘要:The present invention provides a convergent method for the synthesis of ubiquinones and ubiquinone analogues. Also provided are precursors of ubiquinones and their analogues that are useful in the methods of the invention. The invention further provides an improved method for the carboalumination of alkyne substrates.

专利号:US-11008273-B2
优先权日:2019-02-15
标题 :Process for the manufacture of fluorinated benzenes and fluorinated benzophenones, and derivatives thereof
发明人：ZHOU CHANGYUE; DU HONGJUN; WU WENTING
权利人:FUJIAN YONGJING TECH CO LTD
摘要:The invention relates to a new process for the manufacture or synthesis, respectively, of fluorinated benzenes and fluorinated benzophenones, and derivatives thereof, in particular of fluorobenzenes and derivatives thereof. The present invention particularly pertains to a novel environmentally friendly process for the synthesis of fluorinated benzenes and benzophenones as raw materials for the manufacture of polyaryletherketones (PAEKs).

专利号:US-7514465-B2
优先权日:2004-11-16
标题 :Synthesis of N2-(substituted arylmethyl)-3-(substituted phenyl)indazoles as novel anti-angiogenic agents
发明人：KUO SHENG-CHU; HUANG LI-JIAU; LEE FANG-YU; TENG CHE-MING; SHIH MEI-LING; CHEN HUA-SIN
权利人:YUNG SHIN PHARM IND CO LTD
摘要:Novel compounds of 2-(substituted arylmethyl)-3-(substituted phenyl)-2H-indazoles and 1-(substituted arylmethyl)-3-(substituted phenyl)-1H-indazoles are synthesized, and useful as anti-angiogenic agents.

专利号:US-7393954-B2
优先权日:2002-12-12
标题:Process for the production of pentostatin aglycone and pentostatin
发明人：NADJI SOURENA; SMOOT JAMES; SAMPATH UMASHANKER
权利人:RELIABLE BIOPHARMACEUTICAL COR
摘要:A novel, scaleable and improved process for preparing pentostatin and its analogs is disclosed. The method comprises the diastereospecific synthesis of the nucleobase from commercially available L-Dialkyl tartarates.

专利号:US-11608349-B2
优先权日:2019-07-28
标 题:Preparation and application of mixed-ligand nickel(II) complex containing bisoxazoline-derived nitrogen heterocyclic carbene ligand and phosphite ligand
发明人：SUN HONGMEI
权利人:UNIV SOOCHOW
摘要:The invention discloses a mixed Ni(II) complex containing bisoxazoline-derived nitrogen heterocyclic carbene ligand and phosphite ligand and application thereof; the chemical formula of the mixed Ni(II) complex is Ni(NHC)[P(OR) 3 ]X 2 , wherein R is ethyl or isopropyl, X is bromine or chlorine, and NHC is a bisoxazoline-derived nitrogen heterocyclic carbene ligand. In the presence of magnesium shavings, the mixed Ni(II) complex containing bisoxazoline-derived nitrogen heterocyclic carbene ligand and phosphite ligand of the present invention can catalyze low-activity chlorinated aromatic hydrocarbons and fluorinated aromatic hydrocarbons with chlorinated benzyl compounds, respectively, reductive cross-coupling reaction at a single temperature, generating a diarylmethane compound in one step, providing a new method for the synthesis of diarylmethane compounds.