CAS: 4179-19-5; 3,5-Dimethoxytoluene

上下游产品

CAS号7311-34-4 3.5-二甲氧基苯甲醛 | CAS号504-15-4 3,5-二羟基甲苯 | CAS号77-78-1 硫酸二甲酯 | CAS号73569-69-4 1,3-dimethoxy-5... | CAS号74-88-4 碘甲烷 | CAS号109283-25-2 (3,5-dimethoxyp... | CAS号4341-24-6 5-甲基-1,3-环己二酮 | CAS号6443-69-2 3,4,5-三甲氧基甲苯 | CAS号64286-79-9 3,5-dimethoxy-1... | CAS号3209-13-0 3-甲氧基-5-甲基苯酚 | CAS号319921-60-3 2, 4-二甲氧基-6-甲基苯甲腈 | CAS号480-64-8 苔色酸 | CAS号4341-24-6 5-甲基-1,3-环己二酮 | CAS号504-15-4 3,5-二羟基甲苯 | CAS号22976-41-6 3,3',5,5'-Tetra... | CAS号28495-21-8 1,5-dimethoxy-3... | CAS号27508-87-8 1,5-dimethoxy-3... | CAS号82517-12-2 5-甲基-7-甲氧基异黄酮 | CAS号6110-37-8 2,4-二甲氧基-6-甲基苯甲酸甲酯

3,4,5-三甲氧基甲苯置于氢化钾体系中,用 四氢呋喃 作为反应溶剂,化学反应 24.0H,以87%的收率获得产物3,5-二甲氧基甲苯
参考文献:A New Synthesis Of 1-N-Alkyl-3,5-Dimethoxybenzenes (Olivetol Dimethyl Ether And Homologs)
标题:A New Synthesis Of 1-N-Alkyl-3,5-Dimethoxybenzenes (Olivetol Dimethyl Ether And Homologs)
摘要:报告了一种高效的方法,用于合成1-N-烷基-3,5-二甲氧基苯,这是一种在合成大麻素中有用的中间体,来源于易得且廉价的3,4,5-三甲氧基苯甲酸.关键步骤是电子转移诱导的高区域选择性去甲氧基反应,针对1-N-烷基-3,4,5-三甲氧基苯.
DOI:10.1055/s-1989-27135

专利信息

专利号:WO-0140193-A1
优先权日:1999-12-03
标题:Method for the synthesis of pyrazolines
发明人：BOLDI ARMEN M
权利人:CHEMRX ADVANCED TECHNOLOGIES I; BOLDI ARMEN M
摘要:The present invention provides a method for the synthesis of compounds of Formula (I). Also claimed are novel intermediates and their methods of synthesis.

专利号:US-2002103381-A1
优先权日:2000-11-30
标 题 :Method for the synthesis of pyrazolines
发明人：BOLDI ARMEN M
摘要:The present invention provides a method for the synthesis of compounds of Formula I: n n n Also claimed are novel intermediates and their methods of synthesis.

专利号:US-11999757-B2
优先权日:2017-11-01
标 题:Synthesis of boronate ester derivatives and uses thereof
发明人：BOYER SERGE HENRI; HECKER SCOTT J; VERZIJL GERARDUS K M; HERMSEN PETRUS J
权利人:MELINTA SUBSIDIARY CORP
摘要:Disclosed herein are methods for the preparation of boronate derivatives in the synthesis of antimicrobial compounds and uses thereof. Disclosed herein includes method of making a compound of Formula (B) by reducing the ketone group of the keto-ester compound of Formula (A), and the reduction can be performed using a Ruthenium based catalyst system or using an alcohol dehydrogenase bioreduction system.

专利号:US-2008125587-A1
优先权日:2006-05-25
标 题 :Synthesis of triazole compounds that modulate HSP90 activity
发明人：CHIMMANAMADA DINESH U; LEE CHI-WAN; JAMES DAVID; ZHANG SHIJIE; YING WEIWEN; CHAE JUNGHYUN; PRZEWLOKA TERESA
权利人:CHIMMANAMADA DINESH U; LEE CHI-WAN; JAMES DAVID; ZHANG SHIJIE; YING WEIWEN; CHAE JUNGHYUN; PRZEWLOKA TERESA
摘要:The present invention provides novel methods of preparing triazole compounds which inhibit the activity of Hsp90. One embodiment of the invention is directed to methods for preparing a triazole compound represented by the following Structural Formula: n n n n n n n n n n or a tautomer, a pharmaceutically acceptable salt, solvate, or clathrate, or a prodrug thereof, comprising the steps of: a) reacting an amide represented by the following Structural Formula: n n n n n n n n n n with a thionation reagent to form a thioamide; b) reacting the thioamide of step a) with hydrazine to form a hydrazonamide; c) reacting the hydrazonamide of step b) with a carbonylation or a thiocarbonylation reagent. n In one embodiment, the present invention is a method of synthesis of a compound of formula (IA) n n n n n n n n n n or a tautomer, a pharmaceutically acceptable salt, solvate, or clathrate, or a prodrug thereof, comprising reacting a compound of formula (IIA) n n n n n n n n n n with an oxidizing agent, thereby producing a compound of formula (IA). n The present invention is also directed to a method of preparing a compound or a tautomer thereof represented by the following Structural Formula: n n n n n n n n n n or a tautomer, a pharmaceutically acceptable salt, solvate, or clathrate, or a prodrug thereof. The method comprises the step of reacting a first starting compound represented by the following Structural Formula: n n n n n n n n n n in the presence of a mercuric salt, with a second starting compound represented by the following Structural Formula:

专利号:US-10669292-B2
优先权日:2014-05-05
标 题 :Synthesis of boronate salts and uses thereof
发明人：HECKER SCOTT; BOYER SERGE
权利人:REMPEX PHARMACEUTICALS INC
摘要:Disclosed herein are boronate intermediates in the synthesis of antimicrobial compounds and the use and preparation thereof. Some embodiments relate to crystalline boronate salt derivatives and their use in the synthesis of therapeutic compounds.

专利号:US-6133409-A
优先权日:1996-12-19
标 题:Process for the solid phase synthesis of aldehyde, ketone, oxime, amine, hydroxamic acid and αβ-unsaturated carboxylic acid and aldehyde compounds
发明人：SALVINO JOSEPH M; MORTON GEORGE C; MASON HELEN J; LABAUDINIERE RICHARD F
权利人:AVENTIS PHARM PROD INC
摘要:This invention is directed to a process for the solid phase synthesis of aldehyde, ketone, oxime, amine, hydroxamic acid and alpha , beta -unsaturated carboxylic acid and aldehyde compounds and to polymeric hydroxylamine resin compounds useful therefor.