CAS: 573-20-6; 2-Methylnaphthalene-1,4-Diyl Diacetate

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CAS号2211-27-0 1,4-Naphthalene... | CAS号483-55-6 2-羟基-3-甲基-1,4-二...

1.4-Diacetoxy-5.8-Dihydro-2-Metyhl-Naphthalin 反应生成 维生素 K4
参考文献:萘达沙林和2-甲基萘达沙林的某些衍生物
标题:萘达沙林和2-甲基萘达沙林的某些衍生物
摘要:已经发现已知的萘达沙林和2-甲基萘达沙林的制剂会产生副产物,这些副产物已被鉴定.合成了5,8-二羟基-1,3-二甲基萘[2,3-C]呋喃-4,9-醌,并描述了其化学性质;还已经获得了2-溴甲基萘他沙林二乙酸酯.报告了萘醌,它们的前体和衍生物的核磁共振测量结果.
DOI:10.1039/j39670000949

专利信息

专利号:US-9987208-B2
优先权日:2013-04-04
标题 :Elastin synthesis/regeneration promoting agent
发明人：NISHIZAKI TOMOYUKI; TANAKA AKITO
权利人:NISHIZAKI BIOINFORMATION RES INSTITUTE
摘要:8-[2-(2-Pentyl-cyclopropylmethyl)-cyclopropyl]-octanoic acid (DCP-LA) has an action to promote synthesis and regeneration of elastin, and is useful as an agent for the prophylaxis or improvement of wrinkles, and an anti-aging drug.

专利号:US-10144692-B2
优先权日:2014-10-16
标 题 :Method of making vitamin K1
发明人：TIEN JIEN-HEH; PANG CHU-YI; HSU NAI-HSUAN
权利人:SUNNY PHARMTECH INC
摘要:This invention discloses a method of making vitamin K1. The mentioned method of making vitamin K1 comprises performing a first one-pot synthesis with base catalyst, performing a first hydrolysis, performing a substitution, and performing a second one-pot synthesis without metal oxidant. The starting material of this invention is stable 2-methyl-1,4-naphthoquinone. Preferably, this invention provides a method of making vitamin K1 efficiently on simplifying the operation and decreasing the side-product. More preferably, without metal residue, the vitamin K1 of this invention is without metal residue and more safety for clinical application.

专利号:US-6800663-B2
优先权日:2002-10-18
标 题:Crosslinked hydrogel copolymers
发明人：ASGARZADEH FIROUZ; COSTANTINO HENRY R
权利人:ALKERMES INC
摘要:The present invention relates to crosslinked polymers, synthesized through ring-opening polymerization of ethylenically unsaturated epoxides, in combination with α-hydroxy acids using a hydrophilic macroinitiator, such as poly(ethylene glycol), to form substituted copolymers having ethylenically unsaturated functionality randomly distributed along the polyester polymer backbone. That copolymer is subsequently crosslinked to form a hydrogel network. More particularly, the present invention relates to the synthesis of biodegradable poly(α-hydroxy acid-co-glycidyl methacrylate)-block-poly(ethylene glycol)-block-poly(α-hydroxy acid-co-glycidyl methacrylate) copolymers, which are subsequently crosslinked to form hydrogel networks. The invention also relates to the use of these hydrogel networks in various applications, in particular, for the controlled release of drugs and proteins.

专利号:CN-113200837-A
优先权日:2021-05-07
标 题:A new synthesis process of K2-MK tetraene menadione