CAS: 80-73-9; 1,3-Dimethylimidazolidin-2-One

相似化合物

694-32-6 872-69-5 6281-42-1

上下游产品

CAS号201230-82-2 carbon monoxide | CAS号110-70-3 N,N'-二甲基乙二胺 | CAS号136-84-5 1,3-二(羟甲基)-2-咪唑啉酮 | CAS号143-07-7 月桂酸 | CAS号37091-73-9 2-氯-1,3-二甲基氯化咪唑啉 | CAS号124-38-9 二氧化碳 | CAS号13461-16-0 1,3-二甲基咪唑烷-2-硫酮 | CAS号286-20-4 环氧环己烷 | CAS号120-93-4 2-咪唑烷酮 | CAS号77-78-1 硫酸二甲酯 | CAS号37091-73-9 2-氯-1,3-二甲基氯化咪唑啉 | CAS号3367-02-0 2-(2-NAPHTHYL)-... | CAS号1435-43-4 1-氯-3,5-二氟苯 | CAS号141-53-7 甲酸钠 | CAS号110-70-3 N,N'-二甲基乙二胺 | CAS号1633-22-3 对二甲苯二聚体 | CAS号101385-69-7 2-氯-1,3-二甲基咪唑六氟磷酸盐 | CAS号167834-50-6 4-甲氧基-2-甲基喹啉-8-醇 | CAS号189283-51-0 3,4-二氟水杨酸 | CAS号209783-80-2 恩替诺特

1,3-二(羟甲基)-2-咪唑啉酮置于sodium Formate,Potassium Carbonate体系中,用 甲酸 作为反应溶剂,以63%的收率获得产物1,3-二甲基-2-咪唑啉酮
参考文献:Method Of Manufacturing N-Alkyl-N'-Methyl-Alkyleneureas,Particularly N,N'-
标题:Method Of Manufacturing N-Alkyl-N'-Methyl-Alkyleneureas,Particularly N,N'-
摘要:一种制造n-烷基-N'-甲基-烷基脲的方法,通过将烷基脲与甲醛反应反应生成羟甲基-烷基脲,然后将该羟甲基-烷基脲与甲酸进一步反应,得到n-烷基-N'-甲基-烷基脲产物,其中n-烷基-N'-羟甲基-烷基脲或n,N'-(双)羟甲基-烷基脲的摩尔比为1-2至1-10,优选为1-4至1-7.

专利信息

专利号:US-11548898-B2
优先权日:2017-07-06
标题 :Synthesis of halichondrins
发明人：KISHI YOSHITO; AI YANRAN; YE NING; WANG QIAOYI; YAHATA KENZO; ISO Kentaro; NAINI SANTHOSH REDDY; YAMASHITA SHUJI; LEE JIHOON; OHASHI ISAO; FUKUYAMA TAKASHI
权利人:HARVARD COLLEGE; EISAI R&D MAN CO LTD
摘要:The present invention provides methods for the synthesis of ketones involving a Ni/Zr-mediated coupling reaction. The Ni/Zr-mediated ketolization reactions can be used in the synthesis of halichondrins (e.g., halichondrin A, B, C; homohalichondrin A, B, C; norhalichondrin A, B, C), and analogs thereof. Therefore, the present invention also provides synthetic methods useful for the synthesis of halichondrins, and analogs thereof. Also provided herein are compounds (i.e., intermediates) useful in the synthesis of halichondrins, and analogs thereof. In particular, the present invention provides methods and compounds useful in the synthesis of compound of Formula (H3-A).

专利号:US-2004138469-A1
优先权日:2002-12-23
标 题 :Process for the synthesis of torsemide, in particular of pure and stable form II
发明人：LUSSANA MASSIMILIANO; RAINONI MAURO; GAMBUZZA FILIPPO
权利人:COSMA S P A
摘要:The present invention relates to a new process for the synthesis of torsemide, in particular of pure and stable form II, which comprises direct synthesis of torsemide from 4-(3-methylphenylamino)-3-pyridine-sulphonamide. The new process envisages fewer steps than the processes described in the prior art, with improved yields and good quality from the chemical and preferably polymorphous points of view.

专利号:WO-2024105700-A1
优先权日:2022-11-18
标 题:A method for the synthesis of anthranilic amide compounds and intermediates thereof
发明人：MALVIYA NITIN; MAL SANJIB; KLAUSENER ALEXANDER G M
权利人:PI INDUSTRIES LTD
摘要:The present invention discloses a method for the synthesis of a compound of formula (V) or a salt thereof, wherein, R, R1, R2, R3, R4a and R4b are as defined in the detailed description. The method further comprises the synthesis of an anthranilic diamide compound of formula (Z).

专利号:WO-2024058665-A1
优先权日:2022-09-15
标 题:One-pot synthesis of 6-l-[18f] fluoro-3,4-dihydroxyphenylalanine (6-l-[18f] fdopa).
发明人：LUURTSEMA GEERT; KWIZERA CHANTAL; BLOK SIMON NIELS; FARINHA ANTUNES INES; ELSINGA PHILIPPUS HEIN; DE VRIES ERIK
权利人:UNIV GRONINGEN; ACADEMISCH ZIEKENHUIS GRONINGEN
摘要:The invention relates to the field of medicinal chemistry and radiopharmaceuticals, in particular to means, methods and cassettes for the automated synthesis of the radiotracer 6- L -[ 18 F]fluoro-3,4- dihydroxyphenylalanine (6- L -[ 18 F]FDOPA). Provided is a method for the one-pot synthesis of 6- L -[ 18 F]FDOPA comprising contacting a BOC- protected stannyl precursor of the formula I with [ 18 F] Tetraethylammonium fluoride ([ 18 F]Et 4 NF) in the presence of the Cu-catalyst Cu(Impy) 4 (OTf) 2 .

专利号:WO-2025134140-A1
优先权日:2023-12-19
标题:A method for the synthesis of substituted anthranilic amide compounds, intermediates and salts thereof
发明人：MALVIYA NITIN JAIKANT; SINGH VIPENDER; SHAH JIGARKUMAR HARKISHANDAS; KALE MANOJ GANPAT; KAVITAKE SANTOSH GIRIDHAR; BORHADE AJIT SAHEBRAO; KLAUSENER ALEXANDER G M
权利人:PI INDUSTRIES LTD
摘要:The present invention discloses a method for the synthesis of compounds of formula (I) or a salt thereof, wherein, R is selected from hydrogen, halogen, cyano, C1-C12 alkyl, C1-C12 haloalkyl, C1-C12 alkoxy, C1-C12 haloalkoxy, or C3-C8 cycloalkyl; R4 is selected from hydrogen, C1-C12 alkyl, C2-C12 alkenyl, C2-C12 alkynyl, C1-C12 haloalkyl, C2-C12 haloalkenyl, C2-C12 haloalkynyl, C1-C12 alkoxy, C1-C12 haloalkoxy, C3-C8 cycloalkyl, or C3-C8 cycloalkyl-C1-C10 alkyl; and n represents an integer selected from 0-4. The method further comprises the synthesis of an anthranilic diamide compound of formula (A).

专利号:WO-2025134143-A1
优先权日:2023-12-19
标题 :A method for the synthesis of substituted anthranilic amide compounds, intermediates and salts thereof
发明人：MALVIYA NITIN JAIKANT; SINGH VIPENDER; MAL SANJIB; YADAV SANTOSH; SHAH JIGARKUMAR HARKISHANDAS; KAVITAKE SANTOSH GIRIDHAR; BORHADE AJIT SAHEBRAO; KLAUSENER ALEXANDER G M
权利人:PI INDUSTRIES LTD
摘要:The present invention discloses a method for the synthesis of compounds of formula (I) or a salt thereof, wherein R is selected from hydrogen, halogen, cyano, C1-C12 alkyl, C1-C12 haloalkyl, C1-C12 alkoxy, C1-C12 haloalkoxy, or C3-C8 cycloalkyl; R4 is selected from hydrogen, C1-C12 alkyl, C2-C12 alkenyl, C2-C12 alkynyl, C1-C12 haloalkyl, C2- C12 haloalkenyl, C2-C12 haloalkynyl, C1-C12 alkoxy, C1-C12 haloalkoxy, C3-C8 cycloalkyl, or C3-C8 cycloalkyl-C1-C10 alkyl; and n represents an integer selected from 0-4. The process further comprises the synthesis of an anthranilic diamide compound of formula (A).