Oleyl Iodide置于氧气,三正丁基氢锡体系中,用 甲苯 用作溶剂,化学反应 24.0H,反应生成油醇 参考文献:Aerobic Conversion Of Organic Halides To Alcohols. An Oxygenative Radical Cyclization 标题:Aerobic Conversion Of Organic Halides To Alcohols. An Oxygenative Radical Cyclization 摘要: Doi:10.1021/ja00023A076
专利号:US-12252397-B2 优先权日:2019-05-02 标题:Process for the synthesis of nanoparticles of transition metal chalcogenides 发明人:MONIKA MONIKA; PODDAR PANKAJ 权利人:COUNCIL SCIENT IND RES 摘要:A process for the synthesis of transition metal chalcogenides (TMC) having formula (I). More particularly, the present work relates to a one pot single phase process for the synthesis of a TMC system having formula (I) by wet chemistry. Formula (I) is represented as Ax-By.
专利号:US-4922049-A 优先权日:1989-01-13 标 题:Synthesis of cis-olefins 发明人:BYERS JIM D 权利人:PHILLIPS PETROLEUM CO 摘要:A process for the synthesis of cis-olefins from cis-olefinic alcohols consisting essentially of the following steps: n (a) reacting a cis-olefinic alcohol with a source of an alkali metal ion selected from the group consisting of lithium and sodium ions to form a first reaction product, n (b) then contacting said thus formed first reaction product with a sulfonyl halide compound to form a second reaction product, n (c) then containing said thus formed second reaction product with an alkyl magnesium compound and a cuprous salt to form a third reaction product comprising a cis-olefin wherein said steps are carried out in a suitable organic solvent.
专利号:US-9096519-B2 优先权日:2013-01-10 标 题 :Process for the synthesis of ketones from internal alkenes 发明人:MORANDI BILL; GRUBBS ROBERT H; WICKENS ZACHARY K; LERCH MICHAEL M 权利人:CALIFORNIA INST OF TECHN 摘要:The present invention is directed to methods for oxidizing internal olefins to ketones. In various embodiments, each method comprising contacting an organic substrate, having an initial internal olefin, with a mixture of (a) a biscationic palladium salt; and (b) an oxidizing agent; dissolved or dispersed in a solvent system to form a reaction mixture, said solvent system comprising at least one C 2-6 carbon nitrile and optionally at least one secondary alkyl amide, said method conducted under conditions sufficient to convert at least 50 mol % of the initial internal olefin to a ketone, said ketone positioned on a carbon of the initial internal olefin. The transformation occurs at room temperature and shows wide substrate scope. Applications to the oxidation of seed oil derivatives and a bioactive natural product are described.
专利号:US-9517945-B2 优先权日:2012-11-28 标 题:Low-temperature route for precision synthesis of metal oxide nanoparticles 发明人:ITO DAISUKE; HUTCHISON JAMES E 权利人:UNIV OREGON 摘要:Methods for making metal oxide nanoparticles, including mixed metal oxides and core-shell metal oxide nanoparticles, are disclosed. A solution comprising a metal carboxylate and a carboxylic acid is combined with a solvent comprising an alcohol heated to a temperature ≦250° C. for an effective period of time to form metal oxide nanoparticles. The metal may be a group IIIA metal, a group IVA metal, a transition metal, or a combination thereof. A metal oxide shell may be deposited onto metal oxide nanoparticles by dispersing the metal oxide nanoparticles in an alcohol, adding a metal carboxylate, and maintaining the reaction at a temperature ≦200° C. for an effective period of time to form core-shell nanoparticles. The nanoparticles may have a relative size dispersity of ≦20%, and may further comprise a plurality of carboxylic acid, carboxylate, and/or alcohol ligands coordinated to the nanoparticles' outer surfaces.
专利号:US-2006074259-A1 优先权日:2004-10-01 标 题:Process for the enzymatic synthesis of pyroglutamic esters 发明人:PASCALY MATTHIAS; THUM OLIVER 权利人:GOLDSCHMIDT GMBH 摘要:A process for the preparation of compounds according to the general formula (I), n nin which R is a hydrocarbon radical of an alcohol, wherein one or more alcohols of the general formula (II) n nR—OH  (II)n nin which R is as defined above, are esterified and/or transesterified without using significant amounts of solvents, preferably without solvents, preferably under reduced pressure at temperatures below 100° C. in the presence of enzymes from the class of hydrolases with a compound according to the general formula (III), n n nin which R 1 is either hydrogen or a linear or branched alkyl or alkenyl group having 1 to 3 carbon atoms is provided.
专利号:US-4749818-A 优先权日:1987-09-30 标 题:Synthesis of cis-9-tricosene 发明人:BYERS JIM D; DRAKE CHARLES A 权利人:PHILLIPS PETROLEUM CO 摘要:A process for the preparation of cis-9-tricosene is disclosed. Cis-1,9-octadecadiene, which may be obtained by the dehydration of oleyl alcohol, is metallated with an organomagnesium halide, producing cis-9-octadecenylmagnesium halide, which in turn is alkylated with n-pentyl halide to form the desired cis-9-tricosene.
1: Teke GM, Pott RWM. Design and evaluation of a continuous semipartition bioreactor for in situ liquid-liquid extractive fermentation. Biotechnol Bioeng. 2020 Sep 2. doi: 10.1002/bit.27550. Epub ahead of print. 10(1):11367. doi: 10.1038/s41598-020-68399-z. 4: Cordova LT, Butler J, Alper HS. Direct production of fatty alcohols from glucose using engineered strains of Yarrowia lipolytica. Metab Eng Commun. 2019 Oct 31;10:e00105. doi: 10.1016/j.mec.2019.e00105. 5: Jiang Y, Murnane KS, Blough BE, Banga AK. Transdermal Delivery of the Free Base of 3-Fluoroamphetamine: In Vitro Skin Permeation and Irritation Potential. AAPS PharmSciTech. 2020 Mar 25;21(3):109. doi: 10.1208/s12249-020-01649-5. 80(11):2027-2036. doi: 10.2166/wst.2020.015. 9(3):468-474. doi: 10.1021/acssynbio.9b00402. Epub 2020 Mar 9. 55(4):438-447. doi: 10.1080/10934529.2019.1706334. Epub 2020 Mar 9.
合成参考文献
摘要:Vasseur, A.; Bruffaerts, J., Science of Synthesis Knowledge Updates, (2016) 2, 133. 摘要:Kashemirov, B. A.; Błażewska, K.; Justyna, K.; Lyu, J.; McKenna, C. E., Science of Synthesis Knowledge Updates, (2021) 1, 345. 摘要:Kashemirov, B. A.; Błażewska, K.; Justyna, K.; Lyu, J.; McKenna, C. E., Science of Synthesis Knowledge Updates, (2021) 1, 388. 摘要:Besson, M.; Pinel, C., Science of Synthesis: Catalytic Reduction in Organic Synthesis, (2017) 2, 262. 摘要:Shi, Y.; Cole-Hamilton, D. J.; Kamer, P. C. J., Science of Synthesis: Catalytic Reduction in Organic Synthesis, (2017) 2, 204.