合成目标产物 4-Methylbenzhydrol 主要起始原料 Bromobenzene And P-Tolualdehyde
134-84-9 = 1517-63-1 + 808-12-8 反应条件:1.1 Reagents: Tetraethylammonium Perchlorate,Graphite (Reaction Products With Nickel Complex),Ammonium Perchlorate,Nickel(2+),(1,4,8,11-Tetraazacyclotetradecane-6-Ethanol-Kn1,Kn4,Kn8,Kn11)-,(Sp... (Poly(Acrylic Acid)-Bound,Reaction Products With Graphite) Solvents: Acetonitrile; Rt 标题:Electrocatalytic Reduction Of Aldehydes And Ketones On Nickel(Ii) Tetraazamacrocyclic Complex-Modified Graphite Felt Electrode 作者:Kashiwagi,Yoshitomo; Et Al 参考文献:Journal Of Organometallic Chemistry 日期:2002 卷标:662(1-2) 页码:9-13]
134-84-9 = 1517-63-1 + 808-12-8 反应条件:1.1 Reagents: Aluminum,Sodium Chloride,Ammonia 标题:Novel Reduction Of Carbonyl Compounds With Aluminum-Ammonia-Halide Under Irradiation Of Ultrasonic Wave 作者:Sato,Ryu; Et Al 参考文献:Bulletin Of The Chemical Society Of Japan 日期:1990 卷标:63(1) 页码:290-2
专利号:US-8859765-B2 优先权日:2011-11-30 标 题:Process for the manufacture of chiral catalysts and their salts 发明人:WU PING-YU; HENSCHKE JULIAN PAUL 权利人:SCINOPHARM TAIWAN LTD 摘要:The present invention provides efficient and economical methods for synthesis of (−)-2-exo-morpholinoisoborne-10-thiol, its enantiomer, and related chiral catalysts. Novel compounds and methods of asymmetric synthesis are also disclosed.
专利号:US-7176297-B2 优先权日:2002-04-08 标 题:Photoactivatable silane compounds and methods for their synthesis and use 发明人:LI HANDONG; MCGALL GLENN H 权利人:AFFYMETRIX INC 摘要:In one aspect of the invention, photoactivatable silane compounds and methods for their synthesis and use are provided. In one embodiment, the photoactivatable silane compounds synthesized are represented by a formula: PG-LS-SN, wherein PG is a photoactivatable group, LS is a linkage and spacer group, and SN is a silane group. The silanes allow the photoactivatable silane compounds to be covalently bound to the surface of a substrate such as silica. The photoactivatable group forms a hydrophobic layer that can be photochemically cross-linked with a layer of hydrophilic functional polymers. In another embodiment, a method is disclosed to synthesize a substrate of hydrophobic layers and hydrophilic functional polymer layers thereafter onto glass surfaces. An array of biopolymers such as nucleic acids and peptides may then be covalently attached to the substrate using photolithography and biopolymer synthesis.
专利号:US-5780692-A 优先权日:1995-12-28 标 题:Process for producing optically active benzhydrol compounds 发明人:SAKAGUCHI MINZO; IMAI TAKASHI; MIURA TAKASHI; YAMAZAKI TETSURO 权利人:TAKASAGO PERFUMERY CO LTD 摘要:A process for producing a benzhydrol compound (II) which comprises hydrogenating a benzophenone compound (I) in the presence of a hydrogenation catalyst consisting of a transition metal complex, a base and an optically active diamine compound: (I) (II) wherein R1 to R10 each represents H, OH, C1-4 alkyl, C1-4 alkoxy, C1-4 alkanoyl, etc., R2 and R3, and R8 and R9 may form -CH=CH-CH=CH-, or any two of R1 to R9 adjacent to each other may be bonded to thereby form -OCH2O- or -(CH2)3-. By using this process, optically active benzhydrol compounds which have a high purity and are useful as, for example, intermediates in the synthesis of drugs can be produced by simple procedures.
专利号:US-11279734-B2 优先权日:2017-12-01 标 题:Solution-phase affinity selection of inhibitors from combinatorial peptide libraries 发明人:PENTELUTE BRADLEY L; TOUTI FAYCAL 权利人:MASSACHUSETTS INST TECHNOLOGY 摘要:The present invention provides novel peptides (e.g., peptides, macrocyclic peptides, mini-proteins) that modulate protein-protein interactions or salts thereof, and methods of making and using the inventive peptides. In some embodiments, the peptides are high affinity inhibitors (e.g., K D of at most 100 nM, at most 10 nM, at most 1 nM) of a protein-protein interaction. In certain embodiments, these peptides interfere with p53-MDM2 binding interactions (e.g., by binding to MDM2 (GenBank® Gene ID: 4193)). In some embodiments, the peptides interfere with the dimerization of the C-terminal domain of the human immunodeficiency virus (HIV) capsid protein (C-CA), comprising residues 146-231 of the HIV capsid protein (e.g., by binding to the C-terminal domain of the HIV capsid protein (C-CA), thereby inhibiting the dimeric interface of HIV capsid protein, thereby inhibiting viral assembly). These inventive peptides were rapidly generated and identified using novel methods described herein comprising combinatorial peptide synthesis and/or solution affinity selection.
专利号:CN-109053754-B 优先权日:2018-08-15 标 题:Synthesis of polysubstituted chroman compounds based on dearomatization cycloaddition strategy of biomass-derived 2,5-dimethylfuran
专利号:CN-103073372-A 优先权日:2011-10-25 标 题 :Method for Catalytic Synthesis of Amine Compounds by Functionalized Ionic Liquid
摘要:Zaidlewicz, M.; Pakulski, M. M., Science of Synthesis: Stereoselective Synthesis, (2011) 2, 90. 摘要:Kauffman, M. C.; Walsh, P. J., Science of Synthesis: Stereoselective Synthesis, (2011) 2, 450. 摘要:Couve-Bonnaire, S.; Castanheiro, T.; Bouillon, J.-P., Science of Synthesis: Modern Strategies in Organofluorine Chemistry, (2025) 2.