CAS: 1517-63-1; Phenyl(P-Tolyl)Methanol

该化合物其结构特征为:一个以氢氧基(-OH)和甲基组(-CH3)替代的苯环,其位置为:该化合物在室内温度下无色可粉黄固态,以其芳香特性而著称;在水中略有溶解,但在乙醇和乙醇等有机溶剂中较易溶解.4-甲基苯基氢经常用于有机合成,并作为各种化学品生产的中间体.其氢氧基组有可能选择氢结合,影响其再活性和与其他物质的互动.此外,它可能经历与酒精有关的典型反应,例如氧化和酯化.安全数据表明,与许多有机化合物一样,它应该谨慎处理,因为如果浸入或吸入,它可能会对健康造成危害.在与该物质合作时,应该遵循适当的实验室做法.

结构式图片

相似化合物

134-84-9 885-77-8 91-01-0

欧盟法规

ECHA物质C&L通报REACH预注册

上下游产品

CAS号3262-89-3 苯硼酸酐 | CAS号104-87-0 对甲基苯甲醛 | CAS号98-80-6 苯硼酸 | CAS号934-56-5 三甲基苯基锡 | CAS号5720-05-8 对甲基苯基硼酸 | CAS号100-52-7 苯甲醛 | CAS号134-84-9 4-甲基二苯甲酮 | CAS号4463-41-6 4-甲基苯硼酸-1,3-丙二醇酯 | CAS号6843-66-9 二苯基二甲氧基硅烷 | CAS号2996-92-1 苯基三甲氧基硅烷 | CAS号55095-21-1 [(4-甲基苯基)(苯基)甲基]胺盐酸盐 | CAS号220322-74-7 1-methyl-4-(1-p... | CAS号19804-27-4 托拉代尔 | CAS号620-83-7 4-甲基二苯甲烷 | CAS号134-84-9 4-甲基二苯甲酮 | CAS号37858-00-7 4,4'-(oxybis(ph... | CAS号16271-22-0 3,3',5,5'-Tetra... | CAS号110047-35-3 bis(4-methoxy-3... | CAS号1083-30-3 1,3-二苯基丙-1-酮 | CAS号14097-24-6 1,3-二苯基丙-1-醇

合成工艺路线路线简述

  • 合成目标产物 4-Methylbenzhydrol 主要起始原料 Bromobenzene And P-Tolualdehyde
  • 134-84-9 = 1517-63-1 + 808-12-8
    反应条件:1.1 Reagents: Tetraethylammonium Perchlorate,Graphite (Reaction Products With Nickel Complex),Ammonium Perchlorate,Nickel(2+),(1,4,8,11-Tetraazacyclotetradecane-6-Ethanol-Kn1,Kn4,Kn8,Kn11)-,(Sp... (Poly(Acrylic Acid)-Bound,Reaction Products With Graphite) Solvents: Acetonitrile; Rt
    标题:Electrocatalytic Reduction Of Aldehydes And Ketones On Nickel(Ii) Tetraazamacrocyclic Complex-Modified Graphite Felt Electrode
    作者:Kashiwagi,Yoshitomo; Et Al
    参考文献:Journal Of Organometallic Chemistry 日期:2002 卷标:662(1-2) 页码:9-13]

    134-84-9 = 1517-63-1 + 808-12-8
    反应条件:1.1 Reagents: Aluminum,Sodium Chloride,Ammonia
    标题:Novel Reduction Of Carbonyl Compounds With Aluminum-Ammonia-Halide Under Irradiation Of Ultrasonic Wave
    作者:Sato,Ryu; Et Al
    参考文献:Bulletin Of The Chemical Society Of Japan 日期:1990 卷标:63(1) 页码:290-2
4-甲基二苯甲酮置于lithium Tert-Butoxide体系中,用 异丙醇 用作溶剂,化学反应 24.0H,以91%的收率获得4-甲基二苯甲醇
参考文献:在温和条件下用异丙醇光驱动 Mpv 型将芳基酮/醛还原为醇
标题:在温和条件下用异丙醇光驱动 Mpv 型将芳基酮/醛还原为醇
摘要:醇是药物,农用化学品和精细化学品的多功能结构基序.在绿色化学方面,非常需要开发更可持续和更具成本效益的将酮/醛转化为醇的工艺.在此,开发了一种使用异丙醇作为还原剂和溶剂,在t-Buoli存在下,在室温空气气氛下将酮/醛还原为醇的直接光驱动策略.这种操作简单的光促进 Meerwein-Ponndorf-Verley (Mpv) 型还原可用于生产各种苯甲醇衍生物,也可应用于生物活性分子和 Peek 模型化合物,展示了其应用潜力.
Doi:10.1039/d1Gc02449C

海关参考信息

专利信息


专利号:US-8859765-B2
优先权日:2011-11-30
标 题:Process for the manufacture of chiral catalysts and their salts
发明人:WU PING-YU; HENSCHKE JULIAN PAUL
权利人:SCINOPHARM TAIWAN LTD
摘要:The present invention provides efficient and economical methods for synthesis of (−)-2-exo-morpholinoisoborne-10-thiol, its enantiomer, and related chiral catalysts. Novel compounds and methods of asymmetric synthesis are also disclosed.

专利号:US-7176297-B2
优先权日:2002-04-08
标 题:Photoactivatable silane compounds and methods for their synthesis and use
发明人:LI HANDONG; MCGALL GLENN H
权利人:AFFYMETRIX INC
摘要:In one aspect of the invention, photoactivatable silane compounds and methods for their synthesis and use are provided. In one embodiment, the photoactivatable silane compounds synthesized are represented by a formula: PG-LS-SN, wherein PG is a photoactivatable group, LS is a linkage and spacer group, and SN is a silane group. The silanes allow the photoactivatable silane compounds to be covalently bound to the surface of a substrate such as silica. The photoactivatable group forms a hydrophobic layer that can be photochemically cross-linked with a layer of hydrophilic functional polymers. In another embodiment, a method is disclosed to synthesize a substrate of hydrophobic layers and hydrophilic functional polymer layers thereafter onto glass surfaces. An array of biopolymers such as nucleic acids and peptides may then be covalently attached to the substrate using photolithography and biopolymer synthesis.

专利号:US-5780692-A
优先权日:1995-12-28
标 题:Process for producing optically active benzhydrol compounds
发明人:SAKAGUCHI MINZO; IMAI TAKASHI; MIURA TAKASHI; YAMAZAKI TETSURO
权利人:TAKASAGO PERFUMERY CO LTD
摘要:A process for producing a benzhydrol compound (II) which comprises hydrogenating a benzophenone compound (I) in the presence of a hydrogenation catalyst consisting of a transition metal complex, a base and an optically active diamine compound: (I) (II) wherein R1 to R10 each represents H, OH, C1-4 alkyl, C1-4 alkoxy, C1-4 alkanoyl, etc., R2 and R3, and R8 and R9 may form -CH=CH-CH=CH-, or any two of R1 to R9 adjacent to each other may be bonded to thereby form -OCH2O- or -(CH2)3-. By using this process, optically active benzhydrol compounds which have a high purity and are useful as, for example, intermediates in the synthesis of drugs can be produced by simple procedures.

专利号:US-11279734-B2
优先权日:2017-12-01
标 题:Solution-phase affinity selection of inhibitors from combinatorial peptide libraries
发明人:PENTELUTE BRADLEY L; TOUTI FAYCAL
权利人:MASSACHUSETTS INST TECHNOLOGY
摘要:The present invention provides novel peptides (e.g., peptides, macrocyclic peptides, mini-proteins) that modulate protein-protein interactions or salts thereof, and methods of making and using the inventive peptides. In some embodiments, the peptides are high affinity inhibitors (e.g., K D of at most 100 nM, at most 10 nM, at most 1 nM) of a protein-protein interaction. In certain embodiments, these peptides interfere with p53-MDM2 binding interactions (e.g., by binding to MDM2 (GenBank® Gene ID: 4193)). In some embodiments, the peptides interfere with the dimerization of the C-terminal domain of the human immunodeficiency virus (HIV) capsid protein (C-CA), comprising residues 146-231 of the HIV capsid protein (e.g., by binding to the C-terminal domain of the HIV capsid protein (C-CA), thereby inhibiting the dimeric interface of HIV capsid protein, thereby inhibiting viral assembly). These inventive peptides were rapidly generated and identified using novel methods described herein comprising combinatorial peptide synthesis and/or solution affinity selection.

专利号:CN-109053754-B
优先权日:2018-08-15
标 题:Synthesis of polysubstituted chroman compounds based on dearomatization cycloaddition strategy of biomass-derived 2,5-dimethylfuran

专利号:CN-103073372-A
优先权日:2011-10-25
标 题 :Method for Catalytic Synthesis of Amine Compounds by Functionalized Ionic Liquid
金坛市春风化工有限公司
⚠️ 未注册 · 未认证企业
⚠️ 该商家尚未完成注册及企业认证,请用户仔细辨别,谨慎交易。
数据来源于公开网络搜索,平台未作核实,请自行辨别。
🏢敬请 企业认领
🏬开设公司展台
📢获取免费会员权益
🎖️点亮专属注册企业标签
📇展现公司完整信息 样本查看立即注册认领 →
网址: http://www.chunfengchem.com
电话: 0519-82892816👤
📞金坛市春风化工有限公司 ⚠️参考联系方式

销售电话:0519-82892816
邮箱:chunfeng@hi2000.com
🆔 联系时候可告知是从"百琢研"平台获取的信息.
⚠️ 声明: 该企业未认证、未认领,请自行辨别信息的真实性和可靠性。咨询或交易时请注意风险评估与信息核实,百琢研不参与任何交易。企业认领注册入口→

⚠️ 未注册 · 未认证企业
注册入口 备注: 📌 数据来源说明:本展台内容基于各搜索引擎等公开数据整理,仅作展示用途。请用户自行辨别 ✉️ 若企业需抹除展台内容或有异议, 请通过页面底部联系方式告知我们,我们会尽快处理。
第 1 / 1 页
现货

供应商参考报价(招募中)

品牌试剂参考报价(招募中)

📌 第三方产品分析报告

✅ COA系统入驻 | 共享模式

合成参考文献


摘要:Zaidlewicz, M.; Pakulski, M. M., Science of Synthesis: Stereoselective Synthesis, (2011) 2, 90.
摘要:Kauffman, M. C.; Walsh, P. J., Science of Synthesis: Stereoselective Synthesis, (2011) 2, 450.
摘要:Couve-Bonnaire, S.; Castanheiro, T.; Bouillon, J.-P., Science of Synthesis: Modern Strategies in Organofluorine Chemistry, (2025) 2.
📝 需求与反馈
尽可能描述清楚需求与问题信息
×

通知